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pro vyhledávání: '"Andrea Wellington"'
Purpose: It has been known for some time that normal retinal signaling is disrupted early on in diabetes, before the onset of the vascular pathologies associated with diabetic retinopathy. There is growing evidence that levels of retinal dopamine, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::652db43451c670ede962aa12c6674146
https://doi.org/10.1101/2020.10.31.363564
https://doi.org/10.1101/2020.10.31.363564
Publikováno v:
Exp Eye Res
Retinal signaling under dark-adapted conditions is perturbed during early diabetes. Additionally, dopamine, the main neuromodulator of retinal light adaptation, is diminished in diabetic retinas. However, it is not known if this dopamine deficiency c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba9b57e56a299a08afcae65945d0a726
https://pubmed.ncbi.nlm.nih.gov/32910942
https://pubmed.ncbi.nlm.nih.gov/32910942
Publikováno v:
Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology. 151:159-172
The distribution of mitochondria is sensitive to physiological stresses and changes in metabolic demands. Consequently, it is important to carefully define the conditions facilitating live imaging of mitochondrial transport in dissected animal prepar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b893e1402ebe728b5737b0482b6da416
https://doi.org/10.1016/j.cbpa.2008.06.023
https://doi.org/10.1016/j.cbpa.2008.06.023
Autor:
Andrea Wellington, Konrad E. Zinsmaier, Migdalia Gonzalez, Milos Babic, Ryan M. Sangston, Gary J. Russo
Mitochondria are dynamically transported in and out of neuronal processes to maintain neuronal excitability and synaptic function. In higher eukaryotes, the mitochondrial GTPase Miro binds Milton/TRAK adaptor proteins linking microtubule motors to mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::171b60776b87cd7d5af161031072a7b6
https://europepmc.org/articles/PMC4388930/
https://europepmc.org/articles/PMC4388930/
Autor:
Sarvari Panchumarthi, Miriam Schoenfield, Milton P. Charlton, Harold L. Atwood, Leo Marin, Andrea Wellington, Fangle Hu, Xiufang Guo, Konrad E. Zinsmaier, Greg T. Macleod
Publikováno v:
Neuron. 47(3):379-393
SummaryWe have identified EMS-induced mutations in Drosophila Miro (dMiro), an atypical mitochondrial GTPase that is orthologous to human Miro (hMiro). Mutant dmiro animals exhibit defects in locomotion and die prematurely. Mitochondria in dmiro muta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56b5c786b4b5ac4b4787149a80fac417
Autor:
Greg T. Macleod, Fangle Hu, Kathryn Louie, Andrea Wellington, Sarvari Panchumarthi, Gary J. Russo, Konrad E. Zinsmaier
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 29(17)
Microtubule-based transport of mitochondria into dendrites and axons is vital for sustaining neuronal function. Transport along microtubule tracks proceeds in a series of plus and minus end-directed movements that are facilitated by kinesin and dynei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d16ca276c8d9bc56f02cfec03612b6
https://pubmed.ncbi.nlm.nih.gov/19403812
https://pubmed.ncbi.nlm.nih.gov/19403812
Autor:
Steve Emmons, Melissa Grover, Brian James, Lynn Manseau, Andrea Wellington, Peter Tolias, John N. Calley
Publikováno v:
Development (Cambridge, England). 126(23)
Spire is a maternal effect locus that affects both the dorsal- ventral and anterior-posterior axes of the Drosophila egg and embryo. It is required for localization of determinants within the developing oocyte to the posterior pole and to the dorsal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62952a50a1023739e99be85443a29615
https://pubmed.ncbi.nlm.nih.gov/10556052
https://pubmed.ncbi.nlm.nih.gov/10556052