Výsledky vyhledávání - "Andrea Vernengo"

Akademický článek

Papain Injection Creates a Nucleotomy-like Cavity for Testing Gels in Intervertebral Discs

Autor: Jan Ulrich Jansen, Graciosa Quelhas Teixeira, Andrea Vernengo, Sybille Grad, Cornelia Neidlinger-Wilke, Hans-Joachim Wilke

Publikováno v: Gels, Vol 10, Iss 9, p 571 (2024)

Biomaterials, such as hydrogels, have an increasingly important role in the development of regenerative approaches for the intervertebral disc. Since animal models usually resist biomaterial injection due to high intradiscal pressure, preclinical tes

Externí odkaz: https://doaj.org/article/20f2e4e535374ff0a14ea263af9465ac

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Akademický článek

Chemonucleolysis combined with dynamic loading for inducing degeneration in bovine caudal intervertebral discs

Autor: Andrea Vernengo, Helen Bumann, Nadine Kluser, Astrid Soubrier, Amra Šećerović, Jan Gewiess, Jan Ulrich Jansen, Cornelia Neidlinger-Wilke, Hans-Joachim Wilke, Sibylle Grad

Publikováno v: Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)

Chemonucleolysis has become an established method of producing whole organ culture models of intervertebral disc (IVD) degeneration. However, the field needs more side-by-side comparisons of the degenerative effects of the major enzymes used in chemo

Externí odkaz: https://doaj.org/article/c3ccd0b8d3f84be689bb39d624f46bc5

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Akademický článek

A comprehensive tool box for large animal studies of intervertebral disc degeneration

Autor: Naomi N. Lee, Elias Salzer, Frances C. Bach, Andres F. Bonilla, James L. Cook, Zulma Gazit, Sibylle Grad, Keita Ito, Lachlan J. Smith, Andrea Vernengo, Hans‐Joachim Wilke, Julie B. Engiles, Marianna A. Tryfonidou

Publikováno v: JOR Spine, Vol 4, Iss 2, Pp n/a-n/a (2021)

Abstract Preclinical studies involving large animal models aim to recapitulate the clinical situation as much as possible and bridge the gap from benchtop to bedside. To date, studies investigating intervertebral disc (IVD) degeneration and regenerat

Externí odkaz: https://doaj.org/article/ee8b289103d74341b34da54f71abb462

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