Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Andrea Vecchi"'
High CD49a+ NK cell infiltrate is associated with poor clinical outcomes in Hepatocellular Carcinoma
Autor:
Alessandra Zecca, Valeria Barili, Carolina Boni, Paola Fisicaro, Andrea Vecchi, Marzia Rossi, Valentina Reverberi, Anna Montali, Giuseppe Pedrazzi, Carlo Ferrari, Elisabetta Cariani, Gabriele Missale
Publikováno v:
Heliyon, Vol 9, Iss 12, Pp e22680- (2023)
NK cells infiltrating Hepatocellular Carcinoma (HCC) may express residency markers such as Integrin Subunit Alpha 1 (CD49a) that have been associated with nurturing functions in the decidua, and characterized by the production of angiogenic factors a
Externí odkaz:
https://doaj.org/article/9cb91cef7d1848ba8120be1bd442b707
Autor:
Camilla Tiezzi, Marzia Rossi, Andrea Vecchi, Sara Doselli, Amalia Penna, Paola Fisicaro, Ilaria Montali, Camilla Ceccatelli Berti, Valentina Reverberi, Anna Montali, Gabriele Missale, Carlo Ferrari, Carolina Boni
Publikováno v:
STAR Protocols, Vol 4, Iss 4, Pp 102584- (2023)
Summary: Monitoring antigen-specific T cell frequency and function is essential to assess the host immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Here, we present a FluoroSpot assay for concurrently detecti
Externí odkaz:
https://doaj.org/article/1f4b8be0526e456ab475800c1653cc70
Autor:
Camilla Tiezzi, Andrea Vecchi, Marzia Rossi, Davide Cavazzini, Angelo Bolchi, Diletta Laccabue, Sara Doselli, Amalia Penna, Luca Sacchelli, Federica Brillo, Tiziana Meschi, Andrea Ticinesi, Antonio Nouvenne, Gaetano Donofrio, Paola Zanelli, Magda Benecchi, Silvia Giuliodori, Paola Fisicaro, Ilaria Montali, Camilla Ceccatelli Berti, Valentina Reverberi, Anna Montali, Simona Urbani, Giuseppe Pedrazzi, Gabriele Missale, Amalio Telenti, Davide Corti, Simone Ottonello, Carlo Ferrari, Carolina Boni
Publikováno v:
iScience, Vol 26, Iss 6, Pp 106940- (2023)
Summary: Humoral immunity is sensitive to evasion by SARS-CoV-2 mutants, but CD8 T cells seem to be more resistant to mutational inactivation. By a systematic analysis of 30 spike variant peptides containing the most relevant VOC and VOI mutations th
Externí odkaz:
https://doaj.org/article/97b7605f9fec49e3851ab733c6788d02
Autor:
Marco Vivarelli, Federico Mocchegiani, Daniele Nicolini, Andrea Vecchi, Grazia Conte, Enrico Dalla Bona, Roberta Rossi, Andrea Benedetti Cacciaguerra
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Pancreatic resection still represents the only curative option for patients affected by pancreatic ductal adenocarcinoma (PDAC). However, the association with modern chemotherapy regimens is a key factor in improving the inauspicious oncological outc
Externí odkaz:
https://doaj.org/article/fa9d6dbae0c5483a958e833804da9c98
Autor:
Valeria Barili, Paola Fisicaro, Barbara Montanini, Greta Acerbi, Anita Filippi, Giovanna Forleo, Chiara Romualdi, Manuela Ferracin, Francesca Guerrieri, Giuseppe Pedrazzi, Carolina Boni, Marzia Rossi, Andrea Vecchi, Amalia Penna, Alessandra Zecca, Cristina Mori, Alessandra Orlandini, Elisa Negri, Marco Pesci, Marco Massari, Gabriele Missale, Massimo Levrero, Simone Ottonello, Carlo Ferrari
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
Here, the authors report that exhausted HCV-specific CD8+ T cells are marked by upregulation of p53 signaling already detectable in an early phase of chronic HCV infection and by a later development of a repressive chromatin state, and show that chem
Externí odkaz:
https://doaj.org/article/f288f9a480d84b95aefe427ed5f160f3
Autor:
Carolina Boni, Davide Cavazzini, Angelo Bolchi, Marzia Rossi, Andrea Vecchi, Camilla Tiezzi, Valeria Barili, Paola Fisicaro, Carlo Ferrari, Simone Ottonello
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
There is an urgent need for new generation anti-SARS-Cov-2 vaccines in order to increase the efficacy of immunization and its broadness of protection against viral variants that are continuously arising and spreading. The effect of variants on protec
Externí odkaz:
https://doaj.org/article/1e46c90a13f34ee3aa2687dba5db46c8
Publikováno v:
Advances in Applied Energy, Vol 3, Iss , Pp 100047- (2021)
Energy system decarbonisation pathways rely, to a considerable extent, on electricity storage to mitigate the volatility of renewables and ensure high levels of flexibility to future power grids. In this context, liquid air energy storage (LAES) has
Externí odkaz:
https://doaj.org/article/fdaa721fa9264b3cb70c55324b17eda0
Autor:
Ilaria Montali, Andrea Vecchi, Marzia Rossi, Camilla Tiezzi, Amalia Penna, Valentina Reverberi, Diletta Laccabue, Gabriele Missale, Carolina Boni, Paola Fisicaro
Publikováno v:
Biomedicines, Vol 10, Iss 6, p 1224 (2022)
Current treatment for chronic HBV infection is mainly based on nucleos(t)ide analogues, that in most cases need to be administered for a patient’s lifetime. There is therefore a pressing need to develop new therapeutic strategies to shorten antivir
Externí odkaz:
https://doaj.org/article/734d9e8e8a624b708ff54f4ce02dc9df
Autor:
Laura Orsatti, Maria Vittoria Orsale, Pamela di Pasquale, Andrea Vecchi, Fabrizio Colaceci, Alina Ciammaichella, Ilaria Rossetti, Fabio Bonelli, Karsten Baumgaertel, Kai Liu, Daniel Elbaum, Edith Monteagudo
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0251981 (2021)
Coenzyme A (CoA) is a fundamental cofactor involved in a number of important biochemical reactions in the cell. Altered CoA metabolism results in severe conditions such as pantothenate kinase-associated neurodegeneration (PKAN) in which a reduction o
Externí odkaz:
https://doaj.org/article/7e000f01ce6243bdbd931a0aa8f6b26e
Autor:
Paola Fisicaro, Valeria Barili, Marzia Rossi, Ilaria Montali, Andrea Vecchi, Greta Acerbi, Diletta Laccabue, Alessandra Zecca, Amalia Penna, Gabriele Missale, Carlo Ferrari, Carolina Boni
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
A great effort of research has been devoted in the last few years to developing new anti-HBV therapies of finite duration that also provide effective sustained control of virus replication and antigen production. Among the potential therapeutic strat
Externí odkaz:
https://doaj.org/article/e3c4210d58354b6fb33a1528e5d51967