Kinesin superfamily protein Kif26b links Wnt5a-Ror signaling to the control of cell and tissue behaviors in vertebrates

Autor: Michael W Susman, Edith P Karuna, Ryan C Kunz, Taranjit S Gujral, Andrea V Cantú, Shannon S Choi, Brigette Y Jong, Kyoko Okada, Michael K Scales, Jennie Hum, Linda S Hu, Marc W Kirschner, Ryuichi Nishinakamura, Soichiro Yamada, Diana J Laird, Li-En Jao, Steven P Gygi, Michael E Greenberg, Hsin-Yi Henry Ho

Publikováno v: eLife, Vol 6 (2017)

Wnt5a-Ror signaling constitutes a developmental pathway crucial for embryonic tissue morphogenesis, reproduction and adult tissue regeneration, yet the molecular mechanisms by which the Wnt5a-Ror pathway mediates these processes are largely unknown.

Externí odkaz: https://doaj.org/article/275601caa693448db8ac74e33e0585f8

Primordial germ cell migration and the Wnt signaling pathway

Autor: Andrea V. Cantú, Diana J. Laird

Publikováno v: Animal Reproduction. 14:89-101

A critical step in the development of gametes is the migration of their primordial germ cell (PGC) precursors to the forming gonads. Although the location and mode of PGC specification differs between organisms, the formation of a committed germline

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::253b99caa9458e13dd8e601e7eaeb4d5
https://doi.org/10.21451/1984-3143-ar904

Kinesin superfamily protein Kif26b links Wnt5a-Ror signaling to the control of cell and tissue behaviors in vertebrates

Autor: Hsin-Yi Henry Ho, Ryan C. Kunz, Michael K Scales, Ryuichi Nishinakamura, Shannon S. Choi, Taranjit S. Gujral, Li-En Jao, Jennie Hum, Soichiro Yamada, Kyoko Okada, Andrea V. Cantú, Steven P. Gygi, Diana J. Laird, Edith P. Karuna, Brigette Y Jong, Michael E. Greenberg, Linda Hu, Michael W. Susman, Marc W. Kirschner

Publikováno v: eLife
eLife, Vol 6 (2017)

Wnt5a-Ror signaling constitutes a developmental pathway crucial for embryonic tissue morphogenesis, reproduction and adult tissue regeneration, yet the molecular mechanisms by which the Wnt5a-Ror pathway mediates these processes are largely unknown.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47b4bb8ddca231c195cf545fe06b7db0
http://europepmc.org/articles/PMC5590807

Discrete somatic niches coordinate proliferation and migration of primordial germ cells via Wnt signaling

Autor: Diana J. Laird, Andrea V. Cantú, Svetlana Altshuler-Keylin

Publikováno v: The Journal of cell biology, vol 214, iss 2
Cantu, AV; Altshuler-Keylin, S; & Laird, DJ. (2016). Discrete somatic niches coordinate proliferation and migration of primordial germ cells via Wnt signaling. JOURNAL OF CELL BIOLOGY, 214(2), 215-229. doi: 10.1083/jcb.201511061. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/43k7n01g
The Journal of Cell Biology

Mammalian primordial germ cells proliferate while migrating, but the mechanisms regulating these opposing processes remain unclear. Here, Cantú et al. show that somatic cell microenvironments modulate germ cell proliferation via canonical Wnt signal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::497a987c212dcc4a71627774dbd22dc7
https://escholarship.org/uc/item/43k7n01g

In vitro analog of human bone marrow from 3D scaffolds with biomimetic inverted colloidal crystal geometry

Autor: Andrea V. Cantú, Esther Valdivia, Joseph Bielitzki, Ron Mlcak, Matthew L. McClure, Joaquin Cortiella, Nicholas A. Kotov, Ryan Yancy, Jungwoo Lee, Meghan J. Cuddihy, Shaopeng Wang, Jean A. Niles, Joan E. Nichols

Publikováno v: Biomaterials. 30:1071-1079

In vitro replicas of bone marrow can potentially provide a continuous source of blood cells for transplantation and serve as a laboratory model to examine human immune system dysfunctions and drug toxicology. Here we report the development of an in v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08412d944860ddccaf9d12cc0ec64c8e
https://doi.org/10.1016/j.biomaterials.2008.10.041