Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Andrea Toell"'
Publikováno v:
Journal of Cellular Biochemistry. 85:72-82
Constitutive androstane receptor (CAR) and pregnane X receptor (PXR) are members of the nuclear receptor superfamily that regulate target gene transcription in a ligand-dependent manner. CAR and PXR have a rather broad, overlapping set of ligands tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20b8ee699fb7248b69dbea392c2e1fb3
https://doi.org/10.1002/jcb.10104
https://doi.org/10.1002/jcb.10104
Autor:
Andrea Toell, Andreas Steinmeyer, Carsten Carlberg, Seiichi Ishizuka, Manuel Macias Gonzalez, Dagmar Ruf
Publikováno v:
Molecular Pharmacology. 59:1478-1485
Two structurally different antagonists of the nuclear hormone 1alpha,25-dihydroxyvitamin D(3) [1alpha,25(OH)(2)D(3)], the 25-carboxylic ester ZK159222 and the 26,23-lactone TEI-9647, have recently been described. In this study, the molecular mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f6d5bfd0c9d4174cc114d39dc13f58f
https://doi.org/10.1124/mol.59.6.1478
https://doi.org/10.1124/mol.59.6.1478
Publikováno v:
Biochemical Journal. 352:301-309
The vitamin D(3) receptor (VDR), which is the nuclear receptor for 1alpha,25-dihydroxyvitamin D(3) [1alpha,25(OH)(2)D(3)], acts primarily as a heterodimer with the retinoid X receptor (RXR) and binds preferentially to directly repeated arrangements o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6349fff65d7bbf6dbd0e11b26774ee2c
https://doi.org/10.1042/bj3520301
https://doi.org/10.1042/bj3520301
Publikováno v:
Journal of Cellular Biochemistry. 74:386-394
Chronic renal failure is often associated with a resistance to the biologically active form of vitamin D(3), the nuclear hormone 1alpha, 25-dihydroxyvitamin D(3) (VD). The actions of VD are mediated by the vitamin D receptor (VDR), a ligand-dependent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23a55de505c52b92cc53eb30f66f8796
https://doi.org/10.1002/(sici)1097-4644(19990901)74:3<386::aid-jcb7>3.0.co
https://doi.org/10.1002/(sici)1097-4644(19990901)74:3<386::aid-jcb7>3.0.co
Autor:
Markus, Zumbansen, Ludger M, Altrogge, Nicole Ue, Spottke, Sonja, Spicker, Sheila M, Offizier, Sandra Bs, Domzalski, Allison L, St Amand, Andrea, Toell, Devin, Leake, Herbert A, Mueller-Hartmann
Publikováno v:
Journal of RNAi and Gene Silencing : An International Journal of RNA and Gene Targeting Research
Meaningful RNAi-based data for target gene identification are strongly dependent on the use of a biologically relevant cell type and efficient delivery of highly functional siRNA reagents into the selected cell type. Here we report the use of the Ama
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d9ee297ec576d4ecce51d2f63aedbd7f
https://pubmed.ncbi.nlm.nih.gov/20628494
https://pubmed.ncbi.nlm.nih.gov/20628494
Autor:
Jenny Schroeder, Srinivasan Kokatam, Kanchan Tiwari, Andrea Toell, Lubna Hussain, Preeti Kapoor
Publikováno v:
Cancer Research. 75:1388A-1388A
Angiogenesis is a hallmark of most cancers, and is thus an attractive target for the treatment of cancer. One of the easiest screening and target validation strategies for anti-angiogenic target identification involves knocking down targets in Human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36fb21f766ee6a6647d975311835ec67
https://doi.org/10.1158/1538-7445.am2015-1388a
https://doi.org/10.1158/1538-7445.am2015-1388a
Autor:
Bin Tean Teh, Andrea Toell, Filip Farnebo, Peter E. Goretzki, Cornelia Dotzenrath, Catharina Larsson, Ann Svensson, Kenko Cupisti
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 81:3194-3196
Allelic loss of the retinoblastoma tumor suppressor gene has recently been shown to be highly specific for parathyroid carcinoma. It has been proposed that this genetic abnormality may have diagnostic and prognostic implications for parathyroid carci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ab7d0f766d0499e96868e885b174bf8
https://doi.org/10.1210/jcem.81.9.8784068
https://doi.org/10.1210/jcem.81.9.8784068
Publikováno v:
Journal of cellular biochemistry. 85(1)
Constitutive androstane receptor (CAR) and pregnane X receptor (PXR) are members of the nuclear receptor superfamily that regulate target gene transcription in a ligand-dependent manner. CAR and PXR have a rather broad, overlapping set of ligands tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9e439313d191da4e47e8171788bae6d4
https://pubmed.ncbi.nlm.nih.gov/11891851
https://pubmed.ncbi.nlm.nih.gov/11891851
Autor:
Tamara Grabeck, Gina Andretta-Beu, Elke Lorbach, Alexandra Krumnow, Meike Weigel, Sampada Kallol, Sabine Schaepermeier, Stefanie Buesch, Sonja Spicker, Srinivasan Kokatam, Andrea Toell, Ludger Altrogge, Preeti Kapoor, Jenny Schroeder
Publikováno v:
Cancer Research. 74:3485-3485
Cell lines isolated from tumors are an important tool to study cancer in vitro. They can be used for drug development as well as for understanding the basic mechanisms underlying cancer. Transfection of cancer cell lines with different molecules like
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0031695806dcc43bcf3af7fc266f1dcd
https://doi.org/10.1158/1538-7445.am2014-3485
https://doi.org/10.1158/1538-7445.am2014-3485
Publikováno v:
Steroids. 66(3-5)
The vitamin D3 receptor (VDR) acts primarily as a heterodimer with the retinoid X receptor (RXR) on different types of 1a,25dihydroxyvitamin D3 (1a,25(OH)2D3) response elements (VDREs). Therefore, DNA-bound VDR-RXR heterodimers can be considered as t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76bab1d5ed7aeb1b7a81453729a69074
https://pubmed.ncbi.nlm.nih.gov/11179728
https://pubmed.ncbi.nlm.nih.gov/11179728