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Autor:
Allen Zhang, Kavitha Vemuri, Charlie Cong, Shrikant Deshpande, Lourdes Thevanayagam, Andrea Tatum, Dan Derwin, Mohan Srinivasan, Peter Brams, Chetana Rao, Vangipuram S. Rangan, Mary Huber, Bilal Sufi, David Passmore, Sanjeev Gangwar, Tom Kempe, Janette Sung
Publikováno v:
Cancer Research. 70:2587-2587
MDX-1203 is a human anti-CD70 antibody conjugated to a pro-drug containing DNA alkylating cytotoxic Drug A. Drug A is composed of the anti-tumor compound Drug B, containing an ester linked protecting group, and a maleimide containing cleavable peptid