Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Andrea Tanzer"'
Autor:
Lena Hess, Verena Moos, Arnel A Lauber, Wolfgang Reiter, Michael Schuster, Natascha Hartl, Daniel Lackner, Thorina Boenke, Anna Koren, Paloma M Guzzardo, Brigitte Gundacker, Anna Riegler, Petra Vician, Claudia Miccolo, Susanna Leiter, Mahesh B Chandrasekharan, Terezia Vcelkova, Andrea Tanzer, Jun Qi Jun, James Bradner, Gerald Brosch, Markus Hartl, Christoph Bock, Tilmann Bürckstümmer, Stefan Kubicek, Susanna Chiocca, Srividya Bhaskara, Christian Seiser
Publikováno v:
PLoS Genetics, Vol 18, Iss 8, p e1010376 (2022)
The class I histone deacetylases are essential regulators of cell fate decisions in health and disease. While pan- and class-specific HDAC inhibitors are available, these drugs do not allow a comprehensive understanding of individual HDAC function, o
Externí odkaz:
https://doaj.org/article/c86be04b9ac647019e3b6f55aae8c7bf
Autor:
Julien Lagarde, Barbara Uszczynska-Ratajczak, Javier Santoyo-Lopez, Jose Manuel Gonzalez, Electra Tapanari, Jonathan M. Mudge, Charles A. Steward, Laurens Wilming, Andrea Tanzer, Cédric Howald, Jacqueline Chrast, Alicia Vela-Boza, Antonio Rueda, Francisco J. Lopez-Domingo, Joaquin Dopazo, Alexandre Reymond, Roderic Guigó, Jennifer Harrow
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Long non-coding RNAs are increasingly recognised to be important factors in regulating cellular processes and comprise a large faction of the transcriptome, however most are uncharacterised. Here the authors present RACE-Seq, a tool to improve and ex
Externí odkaz:
https://doaj.org/article/4bde9d48e3b14a859a3989164764bb06
Autor:
Vitaly Sedlyarov, Jörg Fallmann, Florian Ebner, Jakob Huemer, Lucy Sneezum, Masa Ivin, Kristina Kreiner, Andrea Tanzer, Claus Vogl, Ivo Hofacker, Pavel Kovarik
Publikováno v:
Molecular Systems Biology, Vol 12, Iss 5, Pp n/a-n/a (2016)
Abstract Precise regulation of mRNA decay is fundamental for robust yet not exaggerated inflammatory responses to pathogens. However, a global model integrating regulation and functional consequences of inflammation‐associated mRNA decay remains to
Externí odkaz:
https://doaj.org/article/e82cc4091db741d6a6c5af1eb76e443d
Publikováno v:
Genes, Vol 9, Iss 8, p 392 (2018)
In this work, we present a computational screen conducted for functional RNA structures, resulting in over 100,000 conserved RNA structure elements found in alignments of mouse (mm10) against 59 other vertebrates. We explicitly included masked repeat
Externí odkaz:
https://doaj.org/article/ebe7d53809694cc7a71d83617107f309
Autor:
Renata Kleinova, Vinod Rajendra, Alina F Leuchtenberger, Claudio Lo Giudice, Cornelia Vesely, Utkarsh Kapoor, Andrea Tanzer, Sophia Derdak, Ernesto Picardi, Michael F Jantsch
Publikováno v:
Nucleic Acids Research. 51:4191-4207
Adenosine deaminase acting on RNA ADAR1 promotes A-to-I conversion in double-stranded and structured RNAs. ADAR1 has two isoforms transcribed from different promoters: cytoplasmic ADAR1p150 is interferon-inducible while ADAR1p110 is constitutively ex
Autor:
Lena Hess, Verena Moos, Arnel A. Lauber, Wolfgang Reiter, Michael Schuster, Natascha Hartl, Daniel Lackner, Thorina Boenke, Anna Koren, Paloma M. Guzzardo, Brigitte Gundacker, Anna Riegler, Petra Vician, Claudia Miccolo, Susanna Leiter, Mahesh B. Chandrasekharan, Terezia Vcelkova, Andrea Tanzer, Jun Qi Jun, James Bradner, Gerald Brosch, Markus Hartl, Christoph Bock, Tilmann Bürckstümmer, Stefan Kubicek, Susanna Chiocca, Srividya Bhaskara, Christian Seiser
Publikováno v:
PLoS genetics. 18(8)
The class I histone deacetylases are essential regulators of cell fate decisions in health and disease. While pan- and class-specific HDAC inhibitors are available, these drugs do not allow a comprehensive understanding of individual HDAC function, o
Publikováno v:
Methods. 156:32-39
Chemical modifications of RNA nucleotides change their identity and characteristics and thus alter genetic and structural information encoded in the genomic DNA. tRNA and rRNA are probably the most heavily modified genes, and often depend on derivati
Autor:
Jules Deforges, Ivo L. Hofacker, Ioannis Xenarios, Yves Poirier, Andrea Tanzer, Veerendra P. Gadekar, Christian Iseli, Rodrigo S. Reis, Shaoline Sheppard, Gene Hart-Smith, Philippe Jacquet
Publikováno v:
Plant physiology, vol. 180, no. 1, pp. 305-322
Cis-Natural Antisense Transcripts (cis-NATs), which overlap protein coding genes and are transcribed from the opposite DNA strand, constitute an important group of noncoding RNAs. Whereas several examples of cis-NATs regulating the expression of thei
Publikováno v:
Bioinformatics
Bioinformatics, Oxford University Press (OUP), 2021
Bioinformatics, Oxford University Press (OUP), 2021
Motivation Predicting the folding dynamics of RNAs is a computationally difficult problem, first and foremost due to the combinatorial explosion of alternative structures in the folding space. Abstractions are therefore needed to simplify downstream
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec58058b2bb482fcd4f9b69674fa1a1f
https://doi.org/10.1101/2020.07.03.186882
https://doi.org/10.1101/2020.07.03.186882
Publikováno v:
Nucleic Acids Research
AREsite2 represents an update for AREsite, an on-line resource for the investigation of AU-rich elements (ARE) in human and mouse mRNA 3'UTR sequences. The new updated and enhanced version allows detailed investigation of AU, GU and U-rich elements (