Výsledky vyhledávání - "Andrea T. Kwaczala"

Decreased polycystin 2 expression alters calcium-contraction coupling and changes β-adrenergic signaling pathways

Autor: Barbara E. Ehrlich, Ivana Y. Kuo, Andrea T. Kwaczala, Kerry S. Russell, Lily Nguyen, Stuart G. Campbell

Publikováno v: Proceedings of the National Academy of Sciences. 111:16604-16609

Cardiac disorders are the main cause of mortality in autosomal-dominant polycystic kidney disease (ADPKD). However, how mutated polycystins predispose patients with ADPKD to cardiac pathologies before development of renal dysfunction is unknown. We i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94671dcbd7bc53dc01aff5e14b957c62
https://doi.org/10.1073/pnas.1415933111

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Anisotropic engineered heart tissue made from laser-cut decellularized myocardium

Autor: Jonas Schwan, Yibing Qyang, Andrea T. Kwaczala, Yongming Ren, Lorenzo R. Sewanan, Oscar Bartulos, Aaron H. Morris, Stuart G. Campbell, Daniel Jacoby, Thomas J. Ryan

Publikováno v: Scientific Reports

We have developed an engineered heart tissue (EHT) system that uses laser-cut sheets of decellularized myocardium as scaffolds. This material enables formation of thin muscle strips whose biomechanical characteristics are easily measured and manipula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6badd28f82f195aea767786ae62650c5
https://doi.org/10.1038/srep32068

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Polycystin 2 expression alters calcium‐contraction coupling

Autor: Lily Nguyen, Barbara E. Ehrlich, Ivana Y. Kuo, Andrea T. Kwaczala, Stuart G. Campbell

Publikováno v: The FASEB Journal. 29

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::936c5dab27b1d95823fb0cdee83f9d19
https://doi.org/10.1096/fasebj.29.1_supplement.946.1

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Alterations in collagen and mineral nanostructure observed in osteoporosis and pharmaceutical treatments using simultaneous small- and wide-angle X-ray scattering

Autor: Andrea T. Kwaczala, Lin Yang, Lisa M. Miller, Stefan Judex, Alvin S. Acerbo

Publikováno v: Calcified tissue international. 95(5)

The influence of the macroscale material properties of bone on its mechanical competence has been extensively investigated, but less is known about possible contributions from bone’s nanoscale material properties. These nanoscale properties, partic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e77f1b1eb335c483339a44f2da961a6a
https://pubmed.ncbi.nlm.nih.gov/25190190

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Moderate intensity resistive exercise improves metaphyseal cancellous bone recovery following an initial disuse period, but does not mitigate decrements during a subsequent disuse period in adult rats

Autor: Corinne E. Metzger, Yasaman Shirazi-Fard, Susan A. Bloomfield, Stefan Judex, Andrea T. Kwaczala, Harry A. Hogan

Publikováno v: Bone. 66

Spaceflight provides a unique environment for skeletal tissue causing decrements in structural and densitometric properties of bone. Previously, we used the adult hindlimb unloaded (HU) rat model to show that previous exposure to HU had minimal effec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c16376cb98270ea4468e668dad60eaab
https://pubmed.ncbi.nlm.nih.gov/24929241

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Previous exposure to simulated microgravity does not exacerbate bone loss during subsequent exposure in the proximal tibia of adult rats

Autor: Rachel A. Anthony, Andrea T. Kwaczala, Harry A. Hogan, Susan A. Bloomfield, Stefan Judex, Yasaman Shirazi-Fard

Publikováno v: Bone. 56(2)

Extended periods of inactivity cause severe bone loss and concomitant deterioration of the musculoskeletal system. Considerable research has been aimed at better understanding the mechanisms and consequences of bone loss due to unloading and the asso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17e43536035d613668617bd1e57a64f6
https://pubmed.ncbi.nlm.nih.gov/23871849

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Fabrication and Characterization of Three-Dimensional Macroscopic All-Carbon Scaffolds

Autor: Sunny C. Patel, Gaurav Lalwani, Stefan Judex, Andrea T. Kwaczala, Shruti Kanakia, Balaji Sitharaman

Publikováno v: Carbon. 53

We report a simple method to fabricate macroscopic, 3-D, free standing, all-carbon scaffolds (porous structures) using multiwalled carbon nanotubes (MWCNTs) as the initial materials. The scaffolds prepared by radical initiated thermal crosslinking, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0be9e7fead78bbe922224c815896e75b
https://pubmed.ncbi.nlm.nih.gov/23436939

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Erratum to 'Moderate intensity resistive exercise improves metaphyseal cancellous bone recovery following an initial disuse period, but does not mitigate decrements during a subsequent disuse period in adult rats' [Bone 66 (2014) 296–305]

Autor: Yasaman Shirazi-Fard, Harry A. Hogan, Stefan Judex, Susan A. Bloomfield, Corinne E. Metzger, Andrea T. Kwaczala

Publikováno v: Bone. 71:265

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7dff3ef0406fc5750743aa727f533ca3
https://doi.org/10.1016/j.bone.2014.08.013

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Decreased Polycystin 2 Expression Alters Calcium-Contraction Coupling and Changes Beta-Adrenergic Signaling Pathways

Autor: Barbara E. Ehrlich, Ivana Y. Kuo, Andrea T. Kwaczala, Stuart G. Campbell, Lily Nguyen

Publikováno v: Biophysical Journal. (2):177a

Cardiac disorders are the main cause of mortality in autosomal dominant polycystic kidney disease (ADPKD). However, how mutated polycystins predispose ADPKD patients to cardiac pathologies before development of renal dysfunction is unknown. We invest

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f0d61054377b8e9471b0cf0fc09adf0

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