Zobrazeno 1 - 10
of 307
pro vyhledávání: '"Andrea Sikora"'
Autor:
Andrea Sikora, Tianyi Zhang, David J. Murphy, Susan E. Smith, Brian Murray, Rishikesan Kamaleswaran, Xianyan Chen, Mitchell S. Buckley, Sandra Rowe, John W. Devlin
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Fluid overload, while common in the ICU and associated with serious sequelae, is hard to predict and may be influenced by ICU medication use. Machine learning (ML) approaches may offer advantages over traditional regression techniques to pre
Externí odkaz:
https://doaj.org/article/cf4fbeec93bb4d0daf307ecf569e5fa7
Autor:
Andrea Sikora, Hayoung Jeong, Mengyun Yu, Xianyan Chen, Brian Murray, Rishikesan Kamaleswaran
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Unsupervised clustering of intensive care unit (ICU) medications may identify unique medication clusters (i.e., pharmacophenotypes) in critically ill adults. We performed an unsupervised analysis with Restricted Boltzmann Machine of 991 medi
Externí odkaz:
https://doaj.org/article/333b1f2986d34ef189d94d671cc4e71c
Autor:
Andrea Sikora, John W. Devlin, Mengyun Yu, Tianyi Zhang, Xianyan Chen, Susan E. Smith, Brian Murray, Mitchell S. Buckley, Sandra Rowe, David J. Murphy
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract While medication regimen complexity, as measured by a novel medication regimen complexity-intensive care unit (MRC-ICU) score, correlates with baseline severity of illness and mortality, whether the MRC-ICU improves hospital mortality predic
Externí odkaz:
https://doaj.org/article/a0b75b6d16b44ee79384d7138fc22823
Autor:
Christine M. Groth, Christopher A. Droege, Preeyaporn Sarangarm, Michaelia D. Cucci, Kyle A. Gustafson, Kathryn A. Connor, Kimberly Kaukeinen, Nicole M. Acquisto, Sai Ho J. Chui, Deepali Dixit, Alexander H. Flannery, Nina E. Glass, Helen Horng, Mojdeh S. Heavner, Justin Kinney, William J. Peppard, Andrea Sikora, Brian L. Erstad
Publikováno v:
Critical Care Research and Practice, Vol 2024 (2024)
Objective. Describe continuous infusion (CI) ketamine practices in pediatric intensive care units (PICUs) and evaluate its effect on pain/sedation scores, exposure to analgesics/sedatives, and adverse effects (AEs). Methods. Multicenter, retrospectiv
Externí odkaz:
https://doaj.org/article/356f19f34f504e1ba77f608f1da19c21
Autor:
Timothy W. Jones, Sultan Almuntashiri, Aaron Chase, Abdullah Alhumaid, Payaningal R. Somanath, Andrea Sikora, Duo Zhang
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-9 (2023)
Abstract Background Matrix metalloproteinase-3 (MMP-3) is a proteolytic enzyme involved in acute respiratory distress syndrome (ARDS) pathophysiology that may serve as a lung-specific biomarker in ARDS. Methods This study was a secondary biomarker an
Externí odkaz:
https://doaj.org/article/87c37b325ed5421d9d97fd044e279372
Autor:
Andrea Sikora, Alireza Rafiei, Milad Ghiasi Rad, Kelli Keats, Susan E. Smith, John W. Devlin, David J. Murphy, Brian Murray, Rishikesan Kamaleswaran, MRC-ICU Investigator Team
Publikováno v:
Critical Care, Vol 27, Iss 1, Pp 1-13 (2023)
Abstract Background Identifying patterns within ICU medication regimens may help artificial intelligence algorithms to better predict patient outcomes; however, machine learning methods incorporating medications require further development, including
Externí odkaz:
https://doaj.org/article/717608b53b034b168b2bc8a6cd12005d
Publikováno v:
Journal of Clinical and Translational Science, Vol 8, Pp 133-133 (2024)
OBJECTIVES/GOALS: To determine if incorporating specific laboratory values and plasma biomarkers (club cell secretory protein (CC16), matrix metalloproteinase 3 (MMP3), interleukin 8 (IL-8), protein C) to the Lung Injury Prediction (LIP) Score improv
Externí odkaz:
https://doaj.org/article/4d5cb619c98c408aa68e233e5810ff00
Publikováno v:
Clinical Medicine Insights: Cardiology, Vol 17 (2023)
Externí odkaz:
https://doaj.org/article/0d087eb12a8f4411b420be2b5c62a536
Publikováno v:
Biology of Sex Differences, Vol 13, Iss 1, Pp 1-9 (2022)
Highlights Plasma TIMP-1 levels are significantly elevated in ARDS patients. Plasma TIMP-1 levels show no difference between female and male ARDS patients. Considering the 30 and 90-day mortality, female non-survivors have significantly higher plasma
Externí odkaz:
https://doaj.org/article/a78b9d81d01641ae8e4c0c3a73312b8d
Autor:
Kelli Keats, PharmD, MPA, BCCCP, Andrea Sikora, PharmD, MSCR, BCCCP, FCCM, Mojdeh S. Heavner, PharmD, BCPS, BCCCP, FCCM, Xianyan Chen, PhD, Susan E. Smith, PharmD, BCPS, BCCCP, FCCM, on behalf of the OPTIM Investigator Team
Publikováno v:
Critical Care Explorations, Vol 5, Iss 9, p e0956 (2023)
BACKGROUND:. The workload of healthcare professionals including physicians and nurses in the ICU has an established relationship to patient outcomes, including mortality, length of stay, and other quality indicators; however, the relationship of crit
Externí odkaz:
https://doaj.org/article/ea1b42755d6049faa65edf9985e7924b