Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Andrea Serio"'
Autor:
Cathleen Hagemann, Matthew C D Bailey, Eugenia Carraro, Ksenia S Stankevich, Valentina Maria Lionello, Noreen Khokhar, Pacharaporn Suklai, Carmen Moreno-Gonzalez, Kelly O'Toole, George Konstantinou, Christina L Dix, Sudeep Joshi, Eleonora Giagnorio, Mads S Bergholt, Christopher D Spicer, Albane Imbert, Francesco Saverio Tedesco, Andrea Serio
Publikováno v:
PLoS Biology, Vol 22, Iss 3, p e3002503 (2024)
Cell culture devices, such as microwells and microfluidic chips, are designed to increase the complexity of cell-based models while retaining control over culture conditions and have become indispensable platforms for biological systems modelling. Fr
Externí odkaz:
https://doaj.org/article/59f8f15ac4084afe9652b3996f842f8d
Autor:
Mads S. Bergholt, Andrea Serio, James S. McKenzie, Amanda Boyd, Renata F. Soares, Jocelyn Tillner, Ciro Chiappini, Vincen Wu, Andreas Dannhorn, Zoltan Takats, Anna Williams, Molly M. Stevens
Publikováno v:
ACS Central Science, Vol 4, Iss 1, Pp 39-51 (2017)
Analyzing lipid composition and distribution within the brain is important to study white matter pathologies that present focal demyelination lesions, such as multiple sclerosis. Some lesions can endogenously re-form myelin sheaths. Therapies aim to
Externí odkaz:
https://doaj.org/article/82a62859ac974cfeb15c7f15800109fa
Autor:
Claire E. Hall, Zhi Yao, Minee Choi, Giulia E. Tyzack, Andrea Serio, Raphaelle Luisier, Jasmine Harley, Elisavet Preza, Charlie Arber, Sarah J. Crisp, P. Marc D. Watson, Dimitri M. Kullmann, Andrey Y. Abramov, Selina Wray, Russell Burley, Samantha H.Y. Loh, L. Miguel Martins, Molly M. Stevens, Nicholas M. Luscombe, Christopher R. Sibley, Andras Lakatos, Jernej Ule, Sonia Gandhi, Rickie Patani
Publikováno v:
Cell Reports, Vol 19, Iss 9, Pp 1739-1749 (2017)
Motor neurons (MNs) and astrocytes (ACs) are implicated in the pathogenesis of amyotrophic lateral sclerosis (ALS), but their interaction and the sequence of molecular events leading to MN death remain unresolved. Here, we optimized directed differen
Externí odkaz:
https://doaj.org/article/550ea2af177d49298d42a25f23b48e54
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 7 (2019)
The extracellular matrix (ECM) consists of a complex mesh of proteins, glycoproteins, and glycosaminoglycans, and is essential for maintaining the integrity and function of biological tissues. Imaging and biomolecular characterization of the ECM is c
Externí odkaz:
https://doaj.org/article/16ae1425845843328d1c2e9ef0ed4d97
Autor:
Sara Iglesias-Rey, Felipe Antunes-Santos, Cathleen Hagemann, David Gómez-Cabrero, Humberto Bustince, Rickie Patani, Andrea Serio, Bernard De Baets, Carlos Lopez-Molina
Publikováno v:
Applied Sciences, Vol 11, Iss 9, p 3733 (2021)
Neurodegenerative diseases are a group of largely incurable disorders characterised by the progressive loss of neurons and for which often the molecular mechanisms are poorly understood. To bridge this gap, researchers employ a range of techniques. A
Externí odkaz:
https://doaj.org/article/60d92d564ba141bea755d0268d76bc5a
Autor:
Chia-Chen Hsu, Andrea Serio, Sahana Gopal, Amy Gelmi, Ciro Chiappini, Ravi A. Desai, Molly M. Stevens
Publikováno v:
ACS Applied Materials & Interfaces. 14:32773-32787
A number of studies have recently shown how surface topography can alter behaviour and differentiation patterns of different types of stem cells. Although the exact mechanisms and molecular pathways involved remain unclear, a consistent portion of th
Autor:
Davide Alessandro Martella, Leor Ariel Rose, Nadia Rouatbi, Chenlei Gu, Valeria Caprettini, Magnus Jensen, Cathleen Hagemann, Andrea Serio, Khuloud Al-Jamal, Maddy Parsons, Mads Bergholt, Paul Brennan, Assaf Zaritsky, Ciro Chiappini
Mapping the molecular composition of tissues using spatial biology provides high-content information for molecular diagnostics. However, spatial biology approaches require invasive procedures to collect samples and destroy the investigated tissue, li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8b0f319872d8e12ec194114a3ab0350
https://doi.org/10.1101/2023.03.09.531882
https://doi.org/10.1101/2023.03.09.531882
Autor:
Cathleen Hagemann, Matthew C. D. Bailey, Valentina Maria Lionello, Noreen Khokhar, Pacharaporn Suklai, Carmen Moreno-Gonzalez, Kelly O’Toole, George Konstantinou, Sudeep Joshi, Eleonora Giagnorio, Mads Bergholt, Albane Imbert, Francesco Saverio Tedesco, Andrea Serio
Cell culture devices, such as microwells and microfluidic chips, are designed to increase the complexity of cell-based models whilst retaining control over culture conditions and have become indispensable platforms for biological systems modelling. F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::336932005ca3ae3abbc4a710b92e604e
https://doi.org/10.1101/2022.02.22.481424
https://doi.org/10.1101/2022.02.22.481424
Engineering models of human skeletal muscle tissue provides unique translational opportunities to investigate and develop therapeutic strategies for acute muscle injuries, and to establish personalised and precision medicine platforms for in vitro st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de2196d8b93dfc09cbbe16de99901d84
Publikováno v:
Brain Communications
RNA binding proteins have been shown to play a key role in the pathogenesis of amyotrophic lateral sclerosis (ALS). Mutations in valosin-containing protein (VCP/p97) cause ALS and exhibit the hallmark nuclear-to-cytoplasmic mislocalization of RNA bin