COVID19 Disease Map, a computational knowledge repository of virus–host interaction mechanisms

Autor: Marek Ostaszewski, Anna Niarakis, Alexander Mazein, Inna Kuperstein, Robert Phair, Aurelio Orta‐Resendiz, Vidisha Singh, Sara Sadat Aghamiri, Marcio Luis Acencio, Enrico Glaab, Andreas Ruepp, Gisela Fobo, Corinna Montrone, Barbara Brauner, Goar Frishman, Luis Cristóbal Monraz Gómez, Julia Somers, Matti Hoch, Shailendra Kumar Gupta, Julia Scheel, Hanna Borlinghaus, Tobias Czauderna, Falk Schreiber, Arnau Montagud, Miguel Ponce de Leon, Akira Funahashi, Yusuke Hiki, Noriko Hiroi, Takahiro G Yamada, Andreas Dräger, Alina Renz, Muhammad Naveez, Zsolt Bocskei, Francesco Messina, Daniela Börnigen, Liam Fergusson, Marta Conti, Marius Rameil, Vanessa Nakonecnij, Jakob Vanhoefer, Leonard Schmiester, Muying Wang, Emily E Ackerman, Jason E Shoemaker, Jeremy Zucker, Kristie Oxford, Jeremy Teuton, Ebru Kocakaya, Gökçe Yağmur Summak, Kristina Hanspers, Martina Kutmon, Susan Coort, Lars Eijssen, Friederike Ehrhart, Devasahayam Arokia Balaya Rex, Denise Slenter, Marvin Martens, Nhung Pham, Robin Haw, Bijay Jassal, Lisa Matthews, Marija Orlic‐Milacic, Andrea Senff-Ribeiro, Karen Rothfels, Veronica Shamovsky, Ralf Stephan, Cristoffer Sevilla, Thawfeek Varusai, Jean‐Marie Ravel, Rupsha Fraser, Vera Ortseifen, Silvia Marchesi, Piotr Gawron, Ewa Smula, Laurent Heirendt, Venkata Satagopam, Guanming Wu, Anders Riutta, Martin Golebiewski, Stuart Owen, Carole Goble, Xiaoming Hu, Rupert W Overall, Dieter Maier, Angela Bauch, Benjamin M Gyori, John A Bachman, Carlos Vega, Valentin Grouès, Miguel Vazquez, Pablo Porras, Luana Licata, Marta Iannuccelli, Francesca Sacco, Anastasia Nesterova, Anton Yuryev, Anita de Waard, Denes Turei, Augustin Luna, Ozgun Babur, Sylvain Soliman, Alberto Valdeolivas, Marina Esteban‐Medina, Maria Peña‐Chilet, Kinza Rian, Tomáš Helikar, Bhanwar Lal Puniya, Dezso Modos, Agatha Treveil, Marton Olbei, Bertrand De Meulder, Stephane Ballereau, Aurélien Dugourd, Aurélien Naldi, Vincent Noël, Laurence Calzone, Chris Sander, Emek Demir, Tamas Korcsmaros, Tom C Freeman, Franck Augé, Jacques S Beckmann, Jan Hasenauer, Olaf Wolkenhauer, Egon L Willighagen, Alexander R Pico, Chris T Evelo, Marc E Gillespie, Lincoln D Stein, Henning Hermjakob, Peter D'Eustachio, Julio Saez‐Rodriguez, Joaquin Dopazo, Alfonso Valencia, Hiroaki Kitano, Emmanuel Barillot, Charles Auffray, Rudi Balling, Reinhard Schneider, the COVID‐19 Disease Map Community

Publikováno v: Molecular Systems Biology, Vol 17, Iss 10, Pp 1-22 (2021)

Abstract We need to effectively combine the knowledge from surging literature with complex datasets to propose mechanistic models of SARS‐CoV‐2 infection, improving data interpretation and predicting key targets of intervention. Here, we describe

Externí odkaz: https://doaj.org/article/07d2352966634fc58ef9a394d1092d67

Prospective Use of Brown Spider Venom Toxins as Therapeutic and Biotechnological Inputs

Autor: Luiza Helena Gremski, Fernando Hitomi Matsubara, Nayanne Louise Costacurta Polli, Bruno Cesar Antunes, Pedro Henrique de Caires Schluga, Hanna Câmara da Justa, João Carlos Minozzo, Ana Carolina Martins Wille, Andrea Senff-Ribeiro, Silvio Sanches Veiga

Publikováno v: Frontiers in Molecular Biosciences, Vol 8 (2021)

Brown spider (genus Loxosceles) venoms are mainly composed of protein toxins used for predation and defense. Bites of these spiders most commonly produce a local dermonecrotic lesion with gravitational spread, edema and hemorrhage, which together are

Externí odkaz: https://doaj.org/article/57685f38071a4c75a7e46d14f9d606e0

Using the Reactome Database

Autor: Karen Rothfels, Marija Milacic, Lisa Matthews, Robin Haw, Cristoffer Sevilla, Marc Gillespie, Ralf Stephan, Chuqiao Gong, Eliot Ragueneau, Bruce May, Veronica Shamovsky, Adam Wright, Joel Weiser, Deidre Beavers, Patrick Conley, Krishna Tiwari, Bijay Jassal, Johannes Griss, Andrea Senff‐Ribeiro, Timothy Brunson, Robert Petryszak, Henning Hermjakob, Peter D'Eustachio, Guanming Wu, Lincoln Stein

Publikováno v: Current Protocols. 3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::31e84af42c769746cb058f4c053d0ad4
https://doi.org/10.1002/cpz1.722

Forty Years of the Description of Brown Spider Venom Phospholipases-D

Autor: Luiza Helena Gremski, Hanna Câmara da Justa, Thaís Pereira da Silva, Nayanne Louise Costacurta Polli, Bruno César Antunes, João Carlos Minozzo, Ana Carolina Martins Wille, Andrea Senff-Ribeiro, Raghuvir Krishnaswamy Arni, Silvio Sanches Veiga

Publikováno v: Toxins, Vol 12, Iss 3, p 164 (2020)

Spiders of the genus Loxosceles, popularly known as Brown spiders, are considered a serious public health issue, especially in regions of hot or temperate climates, such as parts of North and South America. Although the venoms of these arachnids are

Externí odkaz: https://doaj.org/article/501169c8707f4eb7b4337b343584d177

The reactome pathway knowledgebase 2022

Autor: Johannes Griss, Liam Beckman, Cristoffer Sevilla, Lisa Matthews, Solomon Shorser, Julieth Murillo, Chris Sander, Joel Weiser, Ralf Stephan, Konstantinos Sidiropoulos, Chuan Deng, Marija Milacic, Thawfeek M. Varusai, Veronica Shamovsky, Antonio Fabregat, Xiang Shao, Bruce May, Justin Cook, Robin Haw, Nasim Sanati, Emek Demir, Guanming Wu, Gary D. Bader, Karen Rothfels, Chuqiao Gong, Henning Hermjakob, Timothy Brunson, Peter D'Eustachio, Bijay Jassal, Andrea Senff-Ribeiro, Guilherme Viteri, Marc Gillespie, Lincoln Stein, Yusra Haider, Eliot Ragueneau

Publikováno v: Nucleic Acids Research

The Reactome Knowledgebase (https://reactome.org), an Elixir core resource, provides manually curated molecular details across a broad range of physiological and pathological biological processes in humans, including both hereditary and acquired dise

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b6e9fc9b5c93b4fd446c1fe5dd6f31b
https://doi.org/10.1093/nar/gkab1028