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pro vyhledávání: '"Andrea Sartucci"'
Autor:
Francesca Musumeci, Pierpaolo Calandro, Anna Lucia Fallacara, Giulia Vignaroli, David Colecchia, Andrea Sartucci, Alessio Molinari, Mario Chiariello, Adriano Angelucci, Silvia Schenone, Maurizio Botta, Giulia Iovenitti, Claudio Zamperini, Massimo Valoti, Elena Dreassi, Andrea Mancini, Federica Coniglio, Claudio Festuccia, Alessia Calgani
Publikováno v:
Journal of medicinal chemistry. 60(14)
Pyrazolo[3,4-d]pyrimidines are potent protein kinase inhibitors with promising antitumor activity but suboptimal aqueous solubility, consequently worth being further optimized. Herein, we present the one-pot two-step procedure for the synthesis of a