Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Andrea Saponaro"'
Autor:
Alessandro Porro, Andrea Saponaro, Roberta Castelli, Bianca Introini, Anahita Hafez Alkotob, Golnaz Ranjbari, Uta Enke, Jana Kusch, Klaus Benndorf, Bina Santoro, Dario DiFrancesco, Gerhard Thiel, Anna Moroni
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Binding of cAMP to Hyperpolarization activated cyclic nucleotide gated (HCN) channels facilitates pore opening. It is unclear why the isolated cyclic nucleotide binding domain (CNBD) displays in vitro lower affinity for cAMP than the full-le
Externí odkaz:
https://doaj.org/article/54ee296cfd5a4b9b8c10a343ba531e63
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/b2cd7a2a02464eada660d1e2cfbcc7ad
Autor:
Andrea Saponaro, Riccardo Nobile
Publikováno v:
Metals, Vol 14, Iss 1, p 11 (2023)
In the present work, the results of acoustic nonlinear response of ultrasonic wave propagation when monitoring the progress of damage induced by fatigue on notched C45 carbon steel specimens have been reported. Two ultrasound probes were fixed to the
Externí odkaz:
https://doaj.org/article/b07fca9586864aeeb23ccefa42181543
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Tetratricopeptide repeat–containing Rab8b-interacting (TRIP8b) protein is a brain-specific subunit of Hyperpolarization-activated Cyclic Nucleotide-gated (HCN) channels, a class of voltage-gated channels modulated by cyclic nucleotides. While the i
Externí odkaz:
https://doaj.org/article/0cebb3d8efb441d6b45e4e041dc682a9
Autor:
Andrea Saponaro, Marco Lolicato
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/ac91dafab4ff4e2ea4299034001ac10a
Autor:
Joao Luis Carvalho-de-Souza, Andrea Saponaro, C. A. Z. Bassetto, Oliver Rauh, Indra Schroeder, Fabio Franciolini, Luigi Catacuzzeno, Francisco Bezanilla, Gerhard Thiel, Anna Moroni
Publikováno v:
Advances in Physics: X, Vol 7, Iss 1 (2022)
Biological ion channels precisely control the flow of ions across membranes in response to a range of physical and chemical stimuli. With their ability of transporting ions in a highly selective manner and of integrating regulatory cues, they are a s
Externí odkaz:
https://doaj.org/article/dbabf0c9c6e04b96afaf7dcc0631b561
Publikováno v:
Bio-Protocol, Vol 10, Iss 20 (2020)
This protocol illustrates the modelling of a protein-peptide complex using the synergic combination of in silico analysis and experimental results. To this end, we use the integrative modelling software HADDOCK, which possesses the powerful ability t
Externí odkaz:
https://doaj.org/article/1af2eb004c4e43c687ba61168becaa84
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Direct regulation of the pacemaker “funny” current (If) by cyclic AMP (cAMP) underlies heart rate modulation by the autonomic nervous system. At the molecular level, cAMP activates hyperpolarization-activated cyclic nucleotide-gated (HCN) channel
Externí odkaz:
https://doaj.org/article/cb8a090faa094eaaa0d591a3a5ec60c6
Autor:
Alessandro Porro, Andrea Saponaro, Federica Gasparri, Daniel Bauer, Christine Gross, Matteo Pisoni, Gerardo Abbandonato, Kay Hamacher, Bina Santoro, Gerhard Thiel, Anna Moroni
Publikováno v:
eLife, Vol 8 (2019)
Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels control spontaneous electrical activity in heart and brain. Binding of cAMP to the cyclic nucleotide-binding domain (CNBD) facilitates channel opening by relieving a tonic inhibition
Externí odkaz:
https://doaj.org/article/98f511b61e304860a8eb08a7dd5b3536
Autor:
Valentina Nardone, Antonio Chaves-Sanjuan, Michela Lapi, Cristina Airoldi, Andrea Saponaro, Sebastiano Pasqualato, Diletta Dolfini, Carlo Camilloni, Andrea Bernardini, Nerina Gnesutta, Roberto Mantovani, Marco Nardini
Publikováno v:
Cells, Vol 9, Iss 11, p 2370 (2020)
NF-Y is a transcription factor (TF) comprising three subunits (NF-YA, NF-YB, NF-YC) that binds with high specificity to the CCAAT sequence, a widespread regulatory element in gene promoters of prosurvival, cell-cycle-promoting, and metabolic genes. T
Externí odkaz:
https://doaj.org/article/de9008aab41547909f57a8f631950088