Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Andrea S. Pereyra"'
Autor:
Andrea S. Pereyra, Regina F. Fernandez, Adam Amorese, Jasmine N. Castro, Chien-Te Lin, Espen E. Spangenburg, Jessica M. Ellis
Publikováno v:
Molecular Metabolism, Vol 89, Iss , Pp 102015- (2024)
Objective: Abnormal lipid metabolism in mammalian tissues can be highly deleterious, leading to organ failure. Carnitine Palmitoyltransferase 2 (CPT2) deficiency is an inherited metabolic disorder affecting the liver, heart, and skeletal muscle due t
Externí odkaz:
https://doaj.org/article/eafd3a48559b41baa3a61cd052bdf38e
Autor:
Ilya N. Boykov, McLane M. Montgomery, James T. Hagen, Raphael T. Aruleba, Kelsey L. McLaughlin, Hannah S. Coalson, Margaret A. Nelson, Andrea S. Pereyra, Jessica M. Ellis, Tonya N. Zeczycki, Nasreen A. Vohra, Su-Fern Tan, Myles C. Cabot, Kelsey H. Fisher-Wellman
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Targeting mitochondrial oxidative phosphorylation (OXPHOS) to treat cancer has been hampered due to serious side-effects potentially arising from the inability to discriminate between non-cancerous and cancerous mitochondria. Herein, compreh
Externí odkaz:
https://doaj.org/article/de226395575a4fb3a7b262bef6cb95d5
Autor:
Andrea S. Pereyra, Chien-Te Lin, Daniela Mesa Sanchez, Julia Laskin, Espen E. Spangenburg, P. Darrell Neufer, Kelsey Fisher–Wellman, Jessica M. Ellis
Publikováno v:
Molecular Metabolism, Vol 59, Iss , Pp 101456- (2022)
Objective: Skeletal muscle is a heterogeneous and dynamic tissue that adapts to functional demands and substrate availability by modulating muscle fiber size and type. The concept of muscle fiber type relates to its contractile (slow or fast) and met
Externí odkaz:
https://doaj.org/article/9e2c8ea0797d4d65bd364100b70af219
Autor:
Regina F. Fernandez, Andrea S. Pereyra, Victoria Diaz, Emily S. Wilson, Karen A. Litwa, Jonatan Martínez-Gardeazabal, Shelley N. Jackson, J. Thomas Brenna, Brian P. Hermann, Jeffrey B. Eells, Jessica M. Ellis
Publikováno v:
JCI Insight, Vol 6, Iss 11 (2021)
The omega-3 fatty acid docosahexaenoic acid (DHA) inversely relates to neurological impairments with aging; however, limited nondietary models manipulating brain DHA have hindered a direct linkage. We discovered that loss of long-chain acyl-CoA synth
Externí odkaz:
https://doaj.org/article/324c8c40f386458cb32260dddf059dfd
Autor:
Andrea S. Pereyra, Kate L. Harris, Arvin H. Soepriatna, Quin A. Waterbury, Sivakama S. Bharathi, Yuxun Zhang, Kelsey H. Fisher-Wellman, Craig J. Goergen, Eric S. Goetzman, Jessica M. Ellis
Publikováno v:
Journal of Lipid Research, Vol 62, Iss , Pp 100069- (2021)
Long-chain fatty acid oxidation is frequently impaired in primary and systemic metabolic diseases affecting the heart; thus, therapeutically increasing reliance on normally minor energetic substrates, such as ketones and medium-chain fatty acids, cou
Externí odkaz:
https://doaj.org/article/f15fd14b62084072b6c2a245485885ea
Autor:
Pablo Ranea-Robles, Natalya N Pavlova, Aaron Bender, Andrea S Pereyra, Jessica M Ellis, Brandon Stauffer, Chunli Yu, Craig B Thompson, Carmen Argmann, Michelle Puchowicz, Sander M Houten
Publikováno v:
Cardiovasc Res
Aims Cardiomyopathy and arrhythmias can be severe presentations in patients with inherited defects of mitochondrial long-chain fatty acid β-oxidation (FAO). The pathophysiological mechanisms that underlie these cardiac abnormalities remain largely u
Publikováno v:
Diabetes, Obesity and Metabolism. 24:21-33
AIM To compare the molecular and metabolic effects of a single exercise bout in the skeletal muscle between lean and overweight/obese (Ov/Ob) individuals. MATERIALS AND METHODS Participants recruited were men, aged 19-30 years, who were either lean (
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 321:H197-H207
Mouse models of cardiac disease have become essential tools in the study of pathological mechanisms, but the small size of rodents makes it challenging to quantify heart function with noninvasive imaging. Building off recent developments in high-freq
Autor:
Andrea S. Pereyra, Chien-Te Lin, Daniela Mesa Sanchez, Julia Laskin, Espen E. Spangenburg, P. Darrell Neufer, Kelsey Fisher–Wellman, Jessica M. Ellis
Publikováno v:
Molecular metabolism. 59
Skeletal muscle is a heterogeneous and dynamic tissue that adapts to functional demands and substrate availability by modulating muscle fiber size and type. The concept of muscle fiber type relates to its contractile (slow or fast) and metabolic (gly
Publikováno v:
Circulation. 144
Introduction: Progression to heart failure is a known consequence of longstanding hypertrophic cardiomyopathy (HCM); however, routine function markers such as ejection fraction (EF) are often inadequate to predict dysfunction progression. The objecti