Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Andrea S. Link"'
Autor:
Esther Eberhardt, Steven Havlicek, Diana Schmidt, Andrea S. Link, Cristian Neacsu, Zacharias Kohl, Martin Hampl, Andreas M. Kist, Alexandra Klinger, Carla Nau, Jürgen Schüttler, Christian Alzheimer, Jürgen Winkler, Barbara Namer, Beate Winner, Angelika Lampert
Publikováno v:
Stem Cell Reports, Vol 5, Iss 3, Pp 305-313 (2015)
Human pluripotent stem cells (hPSCs) offer the opportunity to generate neuronal cells, including nociceptors. Using a chemical-based approach, we generated nociceptive sensory neurons from HUES6 embryonic stem cells and retrovirally reprogrammed indu
Externí odkaz:
https://doaj.org/article/7b938d91ddc44b31834122252d74feb0
Publikováno v:
e-Neuroforum. 23:105-113
Zusammenfassung Activin ist ein multifunktionales regulatorisches Protein und gehört zur Transforming Growth Factor-β-Familie. Im adulten Gehirn fördert Activin neuronales Überleben bei akuter und chronischer Schädigung. Der Faktor reguliert neu
Autor:
Christian Alzheimer, Steven Havlicek, Johannes Kornhuber, Martin Reichel, Sandra Lehnert, Svitlana Kurinna, Beate Winner, Sabine Werner, Andrea S. Link, Fang Zheng, Tobias Huth
Publikováno v:
Molecular Neurobiology. 53:4210-4225
The transforming growth factor-β (TGF-β) family member activin A exerts multiple neurotrophic and protective effects in the brain. Activin also modulates cognitive functions and affective behavior and is a presumed target of antidepressant therapy.
Publikováno v:
Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience, Vol 9 (2016)
Frontiers in Molecular Neuroscience, Vol 9 (2016)
Activins are members of the transforming growth factor β (TGFβ) family and serve as multifunctional regulatory proteins in many tissues and organs. In the brain, activin A, which is formed by two disulfide-linked βA subunits, is recognized as the
Autor:
Ruth Sittl, Richard W. Carr, Tobias Huth, E. Theresa Schuy, Angelika Lampert, Peter Grafe, Christian Alzheimer, Johannes Fleckenstein, Andrea S. Link
Publikováno v:
Proceedings of the National Academy of Sciences. 109:6704-6709
Infusion of the chemotherapeutic agent oxaliplatin leads to an acute and a chronic form of peripheral neuropathy. Acute oxaliplatin neuropathy is characterized by sensory paresthesias and muscle cramps that are notably exacerbated by cooling. Painful
Autor:
Serdar Uysal, Jochen K. Lennerz, J. Stefan Kaczmarek, Antonio Riccio, David E. Clapham, Alexander Hein, Andrea S. Link, Katharina Zimmermann, John D. Pfeifer, Markus Delling
Publikováno v:
Proceedings of the National Academy of Sciences. 108:18114-18119
Detection and adaptation to cold temperature is crucial to survival. Cold sensing in the innocuous range of cold (>10–15 °C) in the mammalian peripheral nervous system is thought to rely primarily on transient receptor potential (TRP) ion channels
Autor:
Anne Puppel, Fang Zheng, Sabine E. Huber, Volker Eulenburg, Andrea S. Link, Christian P. Müller, Christian Alzheimer, Johannes van Brederode
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 41(8)
Activin, a member of the transforming growth factor-β family, exerts multiple functions in the nervous system. Originally identified as a neurotrophic and -protective agent, increasing evidence implicates activin also in the regulation of glutamater
Autor:
Svitlana Kurinna, Sabine Werner, Aaron J. Huebner, Florian Gruber, Andrea S. Link, Lutz Langbein, Dennis R. Roop, Hans-Dietmar Beer, Konrad Sandhoff, Hany Farwanah, Olivier Sorg, Erwin Tschachler, Jean-Hilaire Saurat, Alexandra Geusau, Ann-Helen Willrodt, Matthias Schäfer, Marlon R. Schneider, Wilhelm Bloch
Publikováno v:
EMBO Molecular Medicine, Vol. 6, No 4 (2014) pp. 442-57
EMBO molecular medicine
EMBO Molecular Medicine, 6 (4)
EMBO molecular medicine
EMBO Molecular Medicine, 6 (4)
The transcription factor Nrf2 is a key regulator of the cellular stress response, and pharmacological Nrf2 activation is a promising strategy for skin protection and cancer prevention. We show here that prolonged Nrf2 activation in keratinocytes caus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32c79d4c712185e5bcbb0a6840c48ab3
https://archive-ouverte.unige.ch/unige:45055
https://archive-ouverte.unige.ch/unige:45055
Autor:
Regina Trollmann, Florian Brackmann, Gail Walkinshaw, Daniel Zoglauer, Christian Alzheimer, M Richter, Susan Jung, Andrea S. Link
Publikováno v:
Brain research. 1531
Activin A is a multifunctional growth and differentiation factor with pronounced neuroprotective properties that is strongly up-regulated in various forms of acute brain disorders and injuries including epilepsy, stroke and trauma. In a pediatric con
Publikováno v:
Cephalalgia : an international journal of headache. 31(1)
Background: Nitrovasodilators, such as glyceroltrinitrate (GTN), which produce nitric oxide (NO) in the organism, are known to cause delayed headaches in migraineurs, accompanied by increased plasma levels of calcitonin gene-related peptide (CGRP) in