Zobrazeno 1 - 10 of 27 pro vyhledávání: '"Andrea S. Heimann"'
1
Akademický článek
Intracellular Peptides in Cell Biology and Pharmacology
Autor: Christiane B. de Araujo, Andrea S. Heimann, Ricardo A. Remer, Lilian C. Russo, Alison Colquhoun, Fábio L. Forti, Emer S. Ferro
Publikováno v: Biomolecules, Vol 9, Iss 4, p 150 (2019)
Intracellular peptides are produced by proteasomes following degradation of nuclear, cytosolic, and mitochondrial proteins, and can be further processed by additional peptidases generating a larger pool of peptides within cells. Thousands of intracel
Externí odkaz: https://doaj.org/article/d3ce3ad7d3864fa293cfb66a60311681
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3
Akademický článek
Generation of G protein-coupled receptor antibodies differentially sensitive to conformational states.
Autor: Andrea S Heimann, Achla Gupta, Ivone Gomes, Rahman Rayees, Avner Schlessinger, Emer S Ferro, Ellen M Unterwald, Lakshmi A Devi
Publikováno v: PLoS ONE, Vol 12, Iss 11, p e0187306 (2017)
The N-terminal region of G protein-coupled receptors can be efficiently targeted for the generation of receptor-selective antibodies. These antibodies are useful for the biochemical characterization of the receptors. In this study, we developed a set
Externí odkaz: https://doaj.org/article/a02462ed03164899bafd13870378401e
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4
Pep19 Has a Positive Effect on Insulin Sensitivity and Ameliorates Both Hepatic and Adipose Tissue Phenotype of Diet-Induced Obese Mice
Autor: Renata Silvério, Robson Barth, Andrea S. Heimann, Patrícia Reckziegel, Gustavo J. dos Santos, Silvana Y. Romero-Zerbo, Francisco J. Bermúdez-Silva, Alex Rafacho, Emer S. Ferro
Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
International Journal of Molecular Sciences; Volume 23; Issue 8; Pages: 4082
Peptide DIIADDEPLT (Pep19) has been previously suggested to improve metabolic parameters, without adverse central nervous system effects, in a murine model of diet-induced obesity. Here, we aimed to further evaluate whether Pep19 oral administration
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::048ec784b203e9c960ca830fcbbdd0e5
https://hdl.handle.net/10668/21149
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5
Peptidomic profiling of cerebrospinal fluid from patients with intracranial saccular aneurysms
Autor: Emer S. Ferro, Ami Navon, Rosangela A. Eichler, Gabriel Reis Sakaya, Andrea S. Heimann, Vitor Nagai Yamaki, Carolina Angélica da Silva Parada, Eberval Gadelha Figueiredo
Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Intracranial saccular aneurysms (ISA) represent 90%–95% of all intracranial aneurysm cases, characterizing abnormal pockets at arterial branch points. Ruptures lead to subarachnoid hemorrhages (SAH) and poor prognoses. We applied mass spectrometry-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::738e3c88c1dcababb9962afeee4dbe31
https://pubmed.ncbi.nlm.nih.gov/33781962
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6
NFKF is a synthetic fragment derived from rat hemopressin that protects mice from neurodegeneration
Autor: Leandro M. Castro, Andrea S. Heimann, Carolina Demarchi Munhoz, Morena Brazil Sant'Anna, Gisele Picolo, Emer S. Ferro, Mayara C. F. Gewehr, Ricardo A. Remer, Aline Carolina Giardini, Nilton Barreto dos Santos
Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Web of Science
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Made available in DSpace on 2020-12-10T19:53:38Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-03-16 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Prev
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca557462ef2adc5be629bf5282bf3957
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7
Intracellular peptides in cell biology and pharmacology
Autor: Lilian C. Russo, Alison Colquhoun, Christiane B. de Araujo, Ricardo A. Remer, Andrea S. Heimann, Emer S. Ferro, Fabio Luis Forti
Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Biomolecules
Biomolecules, Vol 9, Iss 4, p 150 (2019)
Intracellular peptides are produced by proteasomes following degradation of nuclear, cytosolic, and mitochondrial proteins, and can be further processed by additional peptidases generating a larger pool of peptides within cells. Thousands of intracel
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::561a19135d6d0da42a2c437d122ae624
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8
Hemopressin as a breakthrough for the cannabinoid field
Autor: Lakshmi L. Devi, Ricardo Augusto de Melo Reis, Ami Navon, Michal A. Shmuelov, Ivone Gomes, Francisco Silveira Guimarães, Andrea S. Heimann, Camila Squarzoni Dale, Emer S. Ferro, Vanessa Rioli
Publikováno v: Neuropharmacology
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Hemopressin (PVNFKFLSH in rats, and PVNFKLLSH in humans and mice), a fragment derived from the α-chain of hemoglobin, was the first peptide described to have type 1 cannabinoid receptor activity. While hemopressin was shown to have inverse agonist/a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2c1330de9d9b8be9eb1cd4a203c419f
https://doi.org/10.1016/j.neuropharm.2020.108406
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9
A novel peptide that improves metabolic parameters without adverse central nervous system effects
Autor: Karen L. Lopes Jang, Lakshmi A. Devi, Emer S. Ferro, Francisco Silveira Guimarães, Andrea S. Heimann, Naielly S. Rodrigues, Carolina Martinez Romão, Ivone Gomes, Luiz R.G. Britto, Rosangela Aparecida dos Santos Eichler, Nicole Rodrigues da Silva, Achla Gupta, Manoela V. Fogaça, Joel Claudio Heimann, William T. Festuccia, Patrícia Reckziegel
Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Intracellular peptides generated by limited proteolysis are likely to function inside and outside cells and could represent new possibilities for drug development. Here, we used several conformational-sensitive antibodies targeting G-protein coupled
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a524085337da014e1a3a2318b63c79c
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10
Peripheral interactions between cannabinoid and opioid systems contribute to the antinociceptive effect of crotalphine
Autor: Andrea S. Heimann, Yara Cury, A.C.O. Fernandes, F.C. Machado, Gisele Picolo, Vanessa Zambelli
Publikováno v: British Journal of Pharmacology. 171:961-972
Background and Purpose Crotalphine is an antinociceptive peptide that, despite its opioid-like activity, does not induce some of the characteristic side effects of opioids, and its amino acid sequence has no homology to any known opioid peptide. Here
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3592eb95d9ce11c18b07013845eba7dc
https://doi.org/10.1111/bph.12488
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