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pro vyhledávání: '"Andrea Robin Frye"'
Autor:
Sattva S. Neelapu, Seung Tae Lee, Barry L. Gause, Mircea C. Popescu, Larry W. Kwak, Linda K. Harvey, Richard J. Robb, Andrea Robin Frye, Jessie Horton
Publikováno v:
Blood. 109:5160-5163
Clinical studies suggest that treatment with vaccines comprised of idiotype protein may be associated with improved clinical outcome in follicular lymphoma patients. The time-consuming process required to generate patient-specific vaccines is a major
Human autologous tumor-specific T-cell responses induced by liposomal delivery of a lymphoma antigen
Autor:
Barry L. Gause, Richard J. Robb, Mircea C. Popescu, Sivasubramanian Baskar, Robin Pennington, Thelma M. Watson, Elaine S. Jaffe, Sattva S. Neelapu, Larry W. Kwak, Linda K. Harvey, Carol B. Kobrin, Andrea Robin Frye
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 10(24)
Purpose: The idiotype (Id) of the immunoglobulin on a given B-cell malignancy is a clonal marker that can serve as a tumor-specific antigen. We developed a novel vaccine formulation by incorporating Id protein with liposomal lymphokine that was more