Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Andrea Reyna"'
Autor:
Giuseppe Ferrandino, Rachel R. Kaspari, Andrea Reyna-Neyra, Nabil E. Boutagy, Albert J. Sinusas, Nancy Carrasco
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract The sodium/iodide symporter (NIS) mediates active iodide (I−) accumulation in the thyroid, the first step in thyroid hormone (TH) biosynthesis. Mutations in the SLC5A5 gene encoding NIS that result in a non-functional protein lead to conge
Externí odkaz:
https://doaj.org/article/adfd886097eb46a7ac67c7f88e8b5af1
Publikováno v:
Cell Reports, Vol 19, Iss 6, Pp 1083-1090 (2017)
The mammalian target of rapamycin complex 1 (mTORC1) is a master regulator of cell growth that is commonly deregulated in human diseases. Here we find that mTORC1 controls a transcriptional program encoding amino acid transporters and metabolic enzym
Externí odkaz:
https://doaj.org/article/459f6d7488c04317a580767ff625174c
Autor:
Andrea Reyna-Neyra, Sandro M. Hirabara, Lara Jung, Nancy Carrasco, Alejandra Paola Torres-Manzo, Rachel R. Kaspari
Publikováno v:
Proc Natl Acad Sci U S A
Obesity is a major health problem worldwide, given its growing incidence and its association with a variety of comorbidities. Weight gain results from an increase in energy intake without a concomitant increase in energy expenditure. To combat the ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9270b87273b09d098e533d5c41186ad3
https://doi.org/10.1073/pnas.2008919117
https://doi.org/10.1073/pnas.2008919117
Autor:
Nancy Carrasco, Andrea Reyna-Neyra, Geoffrey W. Abbott, Alejandro Llorente-Esteban, L. Mario Amzel, Rían W. Manville
Publikováno v:
Nature Structural & Molecular Biology. 27:533-539
The Na+/I- symporter (NIS), the plasma membrane protein that actively transports I- (stoichiometry 2Na+:1I-) in thyroid physiology and radioiodide-based thyroid cancer treatment, also transports the environmental pollutant perchlorate (stoichiometry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1b21bae0b1f000b2e999d577b7f7294
https://doi.org/10.1038/s41594-020-0417-5
https://doi.org/10.1038/s41594-020-0417-5
Autor:
Given Names Deactivated Family Name Deactivated, Calvin Jones, Arthur Sefiani, Andrea Reyna, Ashley Douthitt, Adel Ghnenis, Cedric g Geoffroy
Publikováno v:
Biology; Volume 11; Issue 4; Pages: 495
Changes in cardiometabolic functions contribute to increased morbidity and mortality after chronic spinal cord injury. Despite many advancements in discovering SCI-induced pathologies, the cardiometabolic risks and divergences in severity-related res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97667fe6f36575218b47e5d934dce153
https://pubmed.ncbi.nlm.nih.gov/35453695
https://pubmed.ncbi.nlm.nih.gov/35453695
Autor:
Mayukh Chakrabarti, Nancy Carrasco, L. Mario Amzel, Mikel X. Suárez, Andrea Reyna-Neyra, Lara Jung
Publikováno v:
Thyroid.
Background: The sodium/iodide (Na+/I−) symporter (NIS) mediates active transport of I− into the thyroid gland. Mutations in the SLC5A5 gene, which encodes NIS, cause I− transport defects (ITDs)—whi...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec64cd5579d283802d0e6961a2aad172
https://doi.org/10.1089/thy.2020.0931
https://doi.org/10.1089/thy.2020.0931
Autor:
Andrea, Reyna-Neyra, Lara, Jung, Mayukh, Chakrabarti, Mikel X, Suárez, L Mario, Amzel, Nancy, Carrasco
Publikováno v:
Thyroid
Background: The sodium/iodide (Na(+)/I(−)) symporter (NIS) mediates active transport of I(−) into the thyroid gland. Mutations in the SLC5A5 gene, which encodes NIS, cause I(−) transport defects (ITDs)—which, if left untreated, lead to congen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7868b4981756f36f6e1ac65345f89849
https://pubmed.ncbi.nlm.nih.gov/33779310
https://pubmed.ncbi.nlm.nih.gov/33779310
Publikováno v:
Annual Review of Physiology. 79:261-289
Active iodide (I−) transport in both the thyroid and some extrathyroidal tissues is mediated by the Na+/I− symporter (NIS). In the thyroid, NIS-mediated I− uptake plays a pivotal role in thyroid hormone (TH) biosynthesis. THs are key during emb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a1e8426ca2070fa79ba97d9578019ad
https://doi.org/10.1146/annurev-physiol-022516-034125
https://doi.org/10.1146/annurev-physiol-022516-034125
Publikováno v:
Cell reports
Cell Reports, Vol 19, Iss 6, Pp 1083-1090 (2017)
Cell Reports, Vol 19, Iss 6, Pp 1083-1090 (2017)
SUMMARY The mammalian target of rapamycin complex 1 (mTORC1) is a master regulator of cell growth that is commonly deregulated in human diseases. Here we find that mTORC1 controls a transcriptional program encoding amino acid transporters and metabol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d464905b7a83572418c707a5f432a714
http://europepmc.org/articles/PMC5811220
http://europepmc.org/articles/PMC5811220
Autor:
Alejandro, Llorente-Esteban, Rían W, Manville, Andrea, Reyna-Neyra, Geoffrey W, Abbott, L Mario, Amzel, Nancy, Carrasco
Publikováno v:
Nature structuralmolecular biology. 27(6)
The Na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bc930769e6d05a5ec9b2cda9ad461ebd
https://pubmed.ncbi.nlm.nih.gov/32472109
https://pubmed.ncbi.nlm.nih.gov/32472109