Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Andrea Resovi"'
Autor:
Andrea Resovi, Perla Persichitti, Laura Brunelli, Lucia Minoli, Patrizia Borsotti, Giulia Garattini, Matteo Tironi, Erica Dugnani, Miriam Redegalli, Giulia De Simone, Roberta Pastorelli, Maria Rosa Bani, Lorenzo Piemonti, Deane F. Mosher, Raffaella Giavazzi, Giulia Taraboletti, Dorina Belotti
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-14 (2023)
Abstract Background The pancreatic microenvironment has a defensive role against cancer but it can acquire tumor-promoting properties triggered by multiple mechanisms including alterations in the equilibrium between proteases and their inhibitors. Th
Externí odkaz:
https://doaj.org/article/4bc68fabcf3a4866bfd7e59ee7c138f6
Autor:
Andrea Resovi, Maria Rosa Bani, Luca Porcu, Alessia Anastasia, Lucia Minoli, Paola Allavena, Paola Cappello, Francesco Novelli, Aldo Scarpa, Eugenio Morandi, Anna Falanga, Valter Torri, Giulia Taraboletti, Dorina Belotti, Raffaella Giavazzi
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 8, Pp 1-14 (2018)
Abstract The clinical management of pancreatic ductal adenocarcinoma (PDAC) is hampered by the lack of reliable biomarkers. This study investigated the value of soluble stroma‐related molecules as PDAC biomarkers. In the first exploratory phase, 12
Externí odkaz:
https://doaj.org/article/e47a6b26a16a45e391d78f0c384f31c5
Autor:
Andrea Resovi, Patrizia Borsotti, Tommaso Ceruti, Alice Passoni, Massimo Zucchetti, Alexander Berndt, Bruce L. Riser, Giulia Taraboletti, Dorina Belotti
Publikováno v:
Cells, Vol 9, Iss 4, p 952 (2020)
The prominent desmoplastic stroma of pancreatic ductal adenocarcinoma (PDAC) is a determinant factor in tumor progression and a major barrier to the access of chemotherapy. The PDAC microenvironment therefore appears to be a promising therapeutic tar
Externí odkaz:
https://doaj.org/article/814b2712dc644b48b6b7bb898871a43d
Autor:
Andrea Resovi, Patrizia Borsotti, Fabio Sangalli, Enrico Davoli, Alexander Berndt, Lorena Zentilin, Massimo Zucchetti, Raffaella Giavazzi, Alice Passoni, Dorina Belotti, Giovanni Valbusa, Denise Pinessi, Mauro Giacca, Giulia Taraboletti, Lavinia Morosi, Elena Carlessi
Publikováno v:
Matrix Biology. :22-36
The disorganized and inefficient tumor vasculature is a major obstacle to the delivery and efficacy of antineoplastic treatments. Antiangiogenic agents can normalize the tumor vessels, improving vessel function and boosting the distribution and activ
Autor:
Andrea David Re Cecconi, Mara Barone, Mara Forti, Martina Lunardi, Alfredo Cagnotto, Mario Salmona, Davide Olivari, Lorena Zentilin, Andrea Resovi, Perla Persichitti, Dorina Belotti, Federica Palo, Nobuyuki Takakura, Hiroyasu Kidoya, Rosanna Piccirillo
Publikováno v:
Cancers; Volume 14; Issue 7; Pages: 1814
Cancer cachexia consists of dramatic body weight loss with rapid muscle depletion due to imbalanced protein homeostasis. We found that the mRNA levels of apelin decrease in muscles from cachectic hepatoma-bearing rats and three mouse models of cachex
Autor:
Katiuscia Bonezzi, Dorina Belotti, Brian J. North, Carmen Ghilardi, Patrizia Borsotti, Andrea Resovi, Paolo Ubezio, Antonella Riva, Raffaella Giavazzi, Eric Verdin, Giulia Taraboletti
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 9, Pp 846-854 (2012)
Taxanes are potent inhibitors of cell motility, a property implicated in their antiangiogenic and antimetastatic activity and unrelated to their antiproliferative effect. The molecular mechanism of this anti-motility activity is poorly understood. In
Externí odkaz:
https://doaj.org/article/324bba01ddad45f9bda06f2d628005cb
Autor:
Dorina Belotti, Massimo Zucchetti, Andrea Resovi, Patrizia Borsotti, Alexander Berndt, Bruce L Riser, Giulia Taraboletti, Alice Passoni, Tommaso Ceruti
Publikováno v:
Cells
Volume 9
Issue 4
Cells, Vol 9, Iss 952, p 952 (2020)
Volume 9
Issue 4
Cells, Vol 9, Iss 952, p 952 (2020)
The prominent desmoplastic stroma of pancreatic ductal adenocarcinoma (PDAC) is a determinant factor in tumor progression and a major barrier to the access of chemotherapy. The PDAC microenvironment therefore appears to be a promising therapeutic tar
Autor:
Giorgia Careccia, Mara Forti, Giulia Benedetta Martinelli, Laura Pasetto, Rosanna Piccirillo, Simonetta Andrea Licandro, Roberto Latini, Giorgio Aquila, Lidia Staszewsky, Andrea David Re Cecconi, Emilie Venereau, Ilaria Russo, Deborah Novelli, Serge Masson, Eugenio Scanziani, Laura Talamini, Roberta Frapolli, Raffaella Giavazzi, Maurizio D'Incalci, Andrea Resovi, Ezia Bello
Publikováno v:
Cancers
Volume 12
Issue 8
Cancers, Vol 12, Iss 2312, p 2312 (2020)
Volume 12
Issue 8
Cancers, Vol 12, Iss 2312, p 2312 (2020)
Trabectedin (ET743) and lurbinectedin (PM01183) limit the production of inflammatory cytokines that are elevated during cancer cachexia. Mice carrying C26 colon adenocarcinoma display cachexia (i.e., premature death and body wasting with muscle, fat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22653c6feaf8258d96aa9fad4c10d870
http://hdl.handle.net/10281/282755
http://hdl.handle.net/10281/282755
Autor:
Raffaella Giavazzi, Giulia Taraboletti, Lavinia Morosi, Alexander Berndt, Andrea Resovi, Denise Pinessi, Massimo Zucchetti, Patrizia Borsotti
Publikováno v:
Cancer Research. 79:198-198
The disorganized and inefficient nature of the tumor vasculature affects the delivery and activity of antineoplastic treatments. Certain antiangiogenic agents induce a transient normalization of tumor vessels, hence representing a promising strategy
Autor:
Luca Porcu, Maria Rosa Bani, Francesco Novelli, Paola Cappello, Alessia Anastasia, Anna Falanga, E. Morandi, Paola Allavena, Aldo Scarpa, Lucia Minoli, Andrea Resovi, Dorina Belotti, Valter Torri, Raffaella Giavazzi, Giulia Taraboletti
Publikováno v:
EMBO Molecular Medicine
EMBO Molecular Medicine, Vol 10, Iss 8, Pp n/a-n/a (2018)
EMBO Molecular Medicine, Vol 10, Iss 8, Pp n/a-n/a (2018)
The clinical management of pancreatic ductal adenocarcinoma (PDAC) is hampered by the lack of reliable biomarkers. This study investigated the value of soluble stroma‐related molecules as PDAC biomarkers. In the first exploratory phase, 12 out of 3