Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Andrea R Tentner"'
Autor:
Andrea R Tentner, Michael J Lee, Gerry J Ostheimer, Leona D Samson, Douglas A Lauffenburger, Michael B Yaffe
Publikováno v:
Molecular Systems Biology, Vol 8, Iss 1, Pp 1-18 (2012)
Abstract Following DNA damage, cells display complex multi‐pathway signaling dynamics that connect cell‐cycle arrest and DNA repair in G1, S, or G2/M phase with phenotypic fate decisions made between survival, cell‐cycle re‐entry and prolifer
Externí odkaz:
https://doaj.org/article/bfd0624a3a6749979c5ea2d602b7ad66
Autor:
Tatiana S. Netterfield, Gerard J. Ostheimer, Andrea R. Tentner, Peter K. Sorger, Kevin A. Janes, Douglas A. Lauffenburger, Michael B. Yaffe
SUMMARYGenotoxic stress in mammalian cells, including that caused by anti-cancer chemotherapy, can induce temporary cell cycle arrest, DNA damage-induced senescence (DDIS) or apoptotic cell death. Despite obvious clinical importance, it is unclear ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4af94c5d574f25a0f922aad0993e87e1
https://doi.org/10.1101/2022.06.15.496288
https://doi.org/10.1101/2022.06.15.496288
SUMMARYDuring neural tube patterning, a gradient of Sonic hedgehog (Shh) signaling specifies ventral progenitor fates. The cellular response to Shh is processed through a genetic regulatory network (GRN) to code distinct fate decisions. This process
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbd06a04b38c900129d0a3bc52e1dcc7
Autor:
Lydie Souhait, Arnaud Gelas, Ian A. Swinburne, Kishore R. Mosaliganti, Fengzhu Xiong, Peng Huang, Nicolas Rannou, Sean G. Megason, Paul D. Cowgill, Andrea R. Tentner, Nikolaus D. Obholzer, Alexander F. Schier
Publikováno v:
Cell. 153(3)
Summary Sharply delineated domains of cell types arise in developing tissues under instruction of inductive signal (morphogen) gradients, which specify distinct cell fates at different signal levels. The translation of a morphogen gradient into discr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0d860192a9299fd4d52679f9edee009
https://pubmed.ncbi.nlm.nih.gov/23622235
https://pubmed.ncbi.nlm.nih.gov/23622235
Autor:
Andrea R Tentner, Gerry J Ostheimer, Michael J. Lee, Leona D. Samson, Michael B. Yaffe, Douglas A. Lauffenburger
Publikováno v:
PMC
Molecular Systems Biology
Molecular Systems Biology
Following DNA damage, cells display complex multi-pathway signaling dynamics that connect cell-cycle arrest and DNA repair in G1, S, or G2/M phase with phenotypic fate decisions made between survival, cell-cycle re-entry and proliferation, permanent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d09cda3efecb76316963d295713dc1c
http://hdl.handle.net/1721.1/74680
http://hdl.handle.net/1721.1/74680
Autor:
Kishore R. Mosaliganti, Tom W. Hiscock, Wenzhe Ma, Nicolas Rannou, Fengzhu Xiong, Nikolaus D. Obholzer, Sean G. Megason, Lydie Souhait, Ian A. Swinburne, Kenneth A. Brakke, Andrea R. Tentner, Arnaud Gelas
Publikováno v:
Cell. (2):415-427
SummaryEpithelial cells acquire functionally important shapes (e.g., squamous, cuboidal, columnar) during development. Here, we combine theory, quantitative imaging, and perturbations to analyze how tissue geometry, cell divisions, and mechanics inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ed84c161b0ed4ad7bad661618d0e087