Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Andrea Peterfi"'
Autor:
Stefan, Holdenrieder, Peter, Eichhorn, Ulrich, Beuers, Walter, Samtleben, Petra, Stieber, Dorothea, Nagel, Andrea, Peterfi, Alexander, Steinle, Helmut Rainer, Salih
Publikováno v:
Anticancer research. 27(4A)
Proteolytic shedding of the immunostimulatory NKG2D ligands MICA and MICB from cancer cells constitutes a novel immune escape strategy that diminishes antitumor reactivity by NKG2D-bearing cytotoxic lymphocytes. In consequence, serum levels of solubl
Autor:
Dagmar Menzel, Anita Bringmann, Hans-Georg Rammensee, Markus P. Radsak, Katrin M. Baltz, Andrea Peterfi, Ingrid Kumbier, Matthias Krusch, Susan Kupka, Peter Brossart, Helmut R. Salih, Stefan Kroeber, Mercedes Kloss, Frank Mayer, Tina Baessler
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 21(10)
Glucocorticoid-induced TNF-related protein (GITR) has been shown to stimulate T cell-mediated antitumor immunity in mice. However, the functional relevance of GITR and its ligand (GITRL) for non-T cells has yet to be fully explored. In addition, rece
Autor:
Petra Stieber, Andrea Peterfi, Dorothea Nagel, Alexander Steinle, Stefan Holdenrieder, Helmut R. Salih
Publikováno v:
Cancer immunology, immunotherapy : CII. 55(12)
Expression of ligands of the immunoreceptor NKG2D such as MICA and MICB has been proposed to play an important role in the immunosurveillance of tumors. Proteolytic shedding of NKG2D ligands from cancer cells therefore constitutes an immune escape me
Autor:
Dorothea Nagel, Helmut R. Salih, Petra Stieber, Stefan Holdenrieder, Andrea Peterfi, Alexander Steinle
Publikováno v:
International journal of cancer. 118(3)
The immunoreceptor NKG2D activates natural killer cells and costimulates CD8 T cells. The MHC class I-related MICA molecules are ligands of NKG2D and are expressed on malignant, but not on normal, cells. As NKG2D plays an important role in the immuno
Autor:
Andrea Peterfi, Katrin M. Baltz, Mercedes Kloss, Tina Baessler, Helmut R. Salih, Ingrid Kumbier, Matthias Krusch, Lothar Kanz
Publikováno v:
Blood. 108:926-926
Members of the TNF superfamily mediate multiple cellular functions, including cellular proliferation, differentiation and cell death. Many members of this protein family are shed from the cell surface as soluble forms, which affects cell-cell interac
Autor:
Mercedes Kloss, Andrea Peterfi, Lothar Kanz, Katrin M. Baltz, Matthias Krusch, Ingrid Kumbier, Helmut R. Salih, Tina Baessler
Publikováno v:
Blood. 108:1941-1941
NK cells play an important role in the reciprocal interaction of tumor cells with the immune system and participate in the surveillance of hematological malignancies including acute myeloid leukemia (AML). Among the molecules influencing host-tumor i
Autor:
Lothar Kanz, Ingrid Kumbier, Mercedes Kloss, Katrin M. Baltz, Helmut R. Salih, Matthias Krusch, Andrea Peterfi
Publikováno v:
Blood. 108:1649-1649
Macrophages are involved in inflammatory and anti-tumor responses by antigen presentation, release of immunoregulatory cytokines and cellular cytotoxicity. Among the molecules influencing macrophage functions are many members of the TNF superfamily.
Autor:
Petra Stieber, Stefan Holdenrieder, Dorothea Nagel, Alexander Steinle, Andrea Peterfi, Helmut R. Salih, Lothar Kanz
Publikováno v:
Blood. 104:1344-1344
The human NKG2D ligands (NKG2DL) MICA and MICB have been shown to be expressed on tumors of epithelial and hematopoietic origin in vivo. Recently we reported that MICA is shed from the cell surface of tumor cells and is present in sera of tumor patie