Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Andrea Pautz"'
Publikováno v:
BMC Oral Health, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background The aim of this study was to investigate the in vitro effect of the antirheumatic drug methotrexate (MTX) on biomechanically compressed human periodontal ligament fibroblasts (hPDLFs), focusing on the expression of interleukin 6 (
Externí odkaz:
https://doaj.org/article/a0243a1dfe9949eaa173887570fa6ad5
Autor:
Sabrina Saurin, Myriam Meineck, Paul Claßen, Simone Cosima Boedecker-Lips, Andrea Pautz, Julia Weinmann-Menke
Publikováno v:
Autoimmunity, Vol 57, Iss 1 (2024)
Animal models are an important tool in the research of chronic autoimmune diseases, like systemic lupus erythematosus (SLE). MRL-Faslpr mice are one of different lupus models that develop spontaneously an SLE-like disease with autoantibodies and immu
Externí odkaz:
https://doaj.org/article/a440d081851f4ae19c99a4bbc980859a
Autor:
Andreas Schwarting, Tamara Möckel, Myriam Meineck, Julia Weinmann-Menke, Andreas Kommer, Sebastian Linsel, Sabrina Saurin, Andrea Pautz
Publikováno v:
Lupus Science and Medicine, Vol 11, Iss Suppl 1 (2024)
Externí odkaz:
https://doaj.org/article/b81d4d40087440d8b23f65ca5d709524
Autor:
Myriam Meineck, Julia Weinmann-Menke, Sabrina Saurin, Andrea Pautz, Till Opatz, Gerhard Erkel
Publikováno v:
Lupus Science and Medicine, Vol 11, Iss Suppl 1 (2024)
Externí odkaz:
https://doaj.org/article/a716c320c8aa4166ab9f3c2fd97d067f
Autor:
Sabrina Saurin, Myriam Meineck, Markus Rohr, Wilfried Roth, Till Opatz, Gerhard Erkel, Andrea Pautz, Julia Weinmann-Menke
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Renal fibrosis is one of the most important triggers of chronic kidney disease (CKD), and only a very limited number of therapeutic options are available to stop fibrosis progression. As fibrosis is characterized by inflammation, myofibro
Externí odkaz:
https://doaj.org/article/5dfc4fcf6eb3433ab945c4433729a681
Autor:
Fabian Gather, Irmgard Ihrig-Biedert, Paul Kohlhas, Tamara Krutenko, Michael Peitz, Oliver Brüstle, Andrea Pautz, Hartmut Kleinert
Publikováno v:
Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-16 (2022)
Abstract Background NOS2 expression is mostly found in bacteria-exposed or cytokine-treated tissues and is mostly connected to innate immune reactions. There are three isoforms of NOS2 (NOS2-1 to -3). In RNA-seq data sets, analyzing inflammatory gene
Externí odkaz:
https://doaj.org/article/ed098a4fb932403ba31cdd861bb334d4
Autor:
Betül R. Erdogan, Martina B. Michel, Jan Matthes, Tamara R. Castañeda, Urs Christen, Ebru Arioglu-Inan, Martin C. Michel, Andrea Pautz
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Diabetes often leads to lower urinary tract dysfunction. The most frequently assessed parameter of urinary bladder dysfunction in animal models of diabetes is an enlargement of the bladder, which is consistently observed in type 1 and l
Externí odkaz:
https://doaj.org/article/3c4c8537885943eba24676d0fef82fd9
Autor:
Zeynep E. Yesilyurt, Jan Matthes, Edith Hintermann, Tamara R. Castañeda, Ralf Elvert, Jesus H. Beltran-Ornelas, Diana L. Silva-Velasco, Ning Xia, Aimo Kannt, Urs Christen, David Centurión, Huige Li, Andrea Pautz, Ebru Arioglu-Inan, Martin C. Michel
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
The urinary bladder is markedly enlarged in the type 1 diabetes mellitus model of streptozotocin-injected rats, which may contribute to the frequent diabetic uropathy. Much less data exists for models of type 2 diabetes. Diabetic polyuria has been pr
Externí odkaz:
https://doaj.org/article/f59087392e074b2ea5f40362b866547a
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 26, Iss 5, Pp 85-101 (2021)
Nitric oxide synthases (NOS) are the major sources of nitric oxide (NO), a small bioactive molecule involved in the regulation of many cellular processes. One of the most prominent functions of NO is regulation of vasodilatation and thereby control o
Externí odkaz:
https://doaj.org/article/be936aac30f540ee9ca1fc311ff2cba4
Autor:
Sabrina Saurin, Myriam Meineck, Gerhard Erkel, Till Opatz, Julia Weinmann-Menke, Andrea Pautz
Publikováno v:
Pharmaceuticals, Vol 15, Iss 5, p 503 (2022)
Most of the immunosuppressive drugs used in the clinic to prevent organ rejection or to treat autoimmune disorders were originally isolated from fungi or bacteria. Therefore, in addition to plants, these are valuable sources for identification of new
Externí odkaz:
https://doaj.org/article/77696af568224a65a20049bc3cdb371b