Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Andrea Ottria"'
Autor:
Alessandro Barbieri, Marzia Dolcino, Elisa Tinazzi, Antonella Rigo, Giuseppe Argentino, Giuseppe Patuzzo, Andrea Ottria, Ruggero Beri, Antonio Puccetti, Claudio Lunardi
Publikováno v:
Journal of Immunology Research, Vol 2015 (2015)
The CD30/CD30L signalling system has been implicated in the pathogenesis of several autoimmune and inflammatory conditions. In rheumatoid arthritis (RA), soluble CD30 (sCD30) levels reflect the recruitment of CD30+ T cells into the inflamed joints an
Externí odkaz:
https://doaj.org/article/3c20c86918a54522a83ca3d6e281ea5a
Autor:
Marzia Dolcino, Andrea Ottria, Alessandro Barbieri, Giuseppe Patuzzo, Elisa Tinazzi, Giuseppe Argentino, Ruggero Beri, Claudio Lunardi, Antonio Puccetti
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128262 (2015)
Psoriatic arthritis (PsA) is an inflammatory arthritis whose pathogenesis is poorly understood; it is characterized by bone erosions and new bone formation. The diagnosis of PsA is mainly clinical and diagnostic biomarkers are not yet available. The
Externí odkaz:
https://doaj.org/article/6da9a397f72b42358cbc10429227b699
Autor:
Marzia Dolcino, Giuseppe Patuzzo, Alessandro Barbieri, Elisa Tinazzi, Monica Rizzi, Ruggero Beri, Giuseppe Argentino, Andrea Ottria, Claudio Lunardi, Antonio Puccetti
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97571 (2014)
BackgroundRegular intravenous immunoglobulin treatment is used to replace antibody deficiency in primary immunodeficiency diseases; however the therapeutic effect seems to be related not only to antibody replacement but also to an active role in the
Externí odkaz:
https://doaj.org/article/1d9ef2abdd8342708dac08ddc6ba3042
Autor:
Marzia Dolcino, Claudio Lunardi, Andrea Ottria, Elisa Tinazzi, Giuseppe Patuzzo, Antonio Puccetti
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115424 (2014)
Psoriatic arthritis (PsA) is a chronic inflammatory disease of unknown origin, characterized by erosions and new bone formation. Diagnosis of PsA is mainly clinical and there are no biomarkers available. Moreover in PsA autoantibodies have not been d
Externí odkaz:
https://doaj.org/article/c28ab9b400794373b76e3be75e052f5e
Autor:
Tiago Carvalheiro, Marzia Rossato, Marta Cossu, Catherina G.K. Wichers, Lorenzo Beretta, Eleni Chouri, Jonas J.W. Kuiper, Femke Bonte-Minheur, Sandra C Silva-Cardoso, Nila H. Servaas, Anneline C Hinrichs, Timothy R D J Radstake, Aridaman Pandit, Nadia Vazirpanah, Alsya J. Affandi, Maarten van der Kroef, Cornelis P. J. Bekker, Andrea Ottria, Marianne Boes, Sanne Hiddingh
Publikováno v:
Arthritis and Rheumatology. John Wiley and Sons Ltd
ObjectivesTo identify key disease pathways driving conventional dendritic cell (cDC) alterations in Systemic Sclerosis (SSc).MethodsTranscriptomic profiling was performed on peripheral blood CD1c+ cDCs (cDC2s) isolated from 12 healthy donors and 48 S
Autor:
Tiago Carvalheiro, Wioleta Marut, M. Inês Pascoal Ramos, Samuel García, Devan Fleury, Alsya J. Affandi, Aniek S. Meijers, Barbara Giovannone, Ralph G. Tieland, Eline Elshof, Andrea Ottria, Marta Cossu, Matthew L. Meizlish, Tineke Veenendaal, Meera Ramanujam, Miguel E. Moreno-García, Judith Klumperman, Nalan Liv, Timothy R.D.J. Radstake, Linde Meyaard
SummaryTissue repair is disturbed in fibrotic diseases like systemic sclerosis (SSc), where the deposition of large amounts of extracellular matrix components such as collagen interferes with organ function. LAIR-1 is an inhibitory collagen receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9be816d427ea40a4f319d28194692d26
https://doi.org/10.1101/2021.12.07.471103
https://doi.org/10.1101/2021.12.07.471103
Autor:
Kris A. Reedquist, Andrea Ottria, Wioleta Marut, Beatriz Malvar Fernandez, Timothy R D J Radstake, Samuel Garcia, Barbara Giovannone, Tiago Carvalheiro
Publikováno v:
Rheumatology (Oxford, England)
Objectives SSc is an autoimmune disease characterized by inflammation, vascular injury and excessive fibrosis in multiple organs. Secreted protein acidic and rich in cysteine (SPARC) is a matricellular glycoprotein that regulates processes involved i
Autor:
Aridaman Pandit, Fatiha Zaaraoui-Boutahar, Sandra C Silva-Cardoso, Rina Kommer-Wichers, Femke van Wijk, Timothy R D J Radstake, Maarten van der Kroef, Andrea Ottria, Eleni Chouri, Arno C. Andeweg, Tiago Ferreira-Carvalheiro, Alsya J. Affandi, Nila H. Servaas
Publikováno v:
Journal of Autoimmunity, 117:102574. Academic Press Inc.
Journal of Autoimmunity, 117:102574. Academic Press
Servaas, N H, Zaaraoui-Boutahar, F, Wichers, C G K, Ottria, A, Chouri, E, Affandi, A J, Silva-Cardoso, S, van der Kroef, M, Carvalheiro, T, van Wijk, F, Radstake, T R D J, Andeweg, A C & Pandit, A 2021, ' Longitudinal analysis of T-cell receptor repertoires reveals persistence of antigen-driven CD4+ and CD8+ T-cell clusters in systemic sclerosis ', Journal of Autoimmunity, vol. 117, 102574, pp. 102574 . https://doi.org/10.1016/j.jaut.2020.102574
Journal of Autoimmunity, 117:102574. Academic Press
Servaas, N H, Zaaraoui-Boutahar, F, Wichers, C G K, Ottria, A, Chouri, E, Affandi, A J, Silva-Cardoso, S, van der Kroef, M, Carvalheiro, T, van Wijk, F, Radstake, T R D J, Andeweg, A C & Pandit, A 2021, ' Longitudinal analysis of T-cell receptor repertoires reveals persistence of antigen-driven CD4+ and CD8+ T-cell clusters in systemic sclerosis ', Journal of Autoimmunity, vol. 117, 102574, pp. 102574 . https://doi.org/10.1016/j.jaut.2020.102574
The T-cell receptor (TCR) is a highly polymorphic surface receptor that allows T-cells to recognize antigenic peptides presented on the major histocompatibility complex (MHC). Changes in the TCR repertoire have been observed in several autoimmune con
Autor:
Alsya J. Affandi, Tiago Carvalheiro, Andrea Ottria, Judith J. de Haan, Maike A.D. Brans, Maarten M. Brandt, Ralph G. Tieland, Ana P. Lopes, Beatriz Malvar Fernández, Cornelis P.J. Bekker, Maarten van der Linden, Maili Zimmermann, Barbara Giovannone, Catharina G.K. Wichers, Samuel Garcia, Michael de Kok, Giuseppina Stifano, Yan Juan Xu, M. Anna Kowalska, Maaike Waasdorp, Caroline Cheng, Susan Gibbs, Saskia C.A. de Jager, Joel A.G. van Roon, Timothy R.D.J. Radstake, Wioleta Marut
Publikováno v:
Cell Reports, 38(1):110189. Cell Press
Affandi, A J, Carvalheiro, T, Ottria, A, de Haan, J J, Brans, M A D, Brandt, M M, Tieland, R G, Lopes, A P, Fernandez, B M, Bekker, C P J, van der Linden, M, Zimmermann, M, Giovannone, B, Wichers, C G K, Garcia, S, de Kok, M, Stifano, G, Xu, Y J, Kowalska, M A, Waasdorp, M, Cheng, C, Gibbs, S, de Jager, S C A, van Roon, J A G, Radstake, T R D J & Marut, W 2022, ' CXCL4 drives fibrosis by promoting several key cellular and molecular processes ', Cell Reports, vol. 38, no. 1, 110189 . https://doi.org/10.1016/j.celrep.2021.110189
Cell Reports, 38(1). Cell Press
Affandi, A J, Carvalheiro, T, Ottria, A, de Haan, J J, Brans, M A D, Brandt, M M, Tieland, R G, Lopes, A P, Fernández, B M, Bekker, C P J, van der Linden, M, Zimmermann, M, Giovannone, B, Wichers, C G K, Garcia, S, de Kok, M, Stifano, G, Xu, Y J, Kowalska, M A, Waasdorp, M, Cheng, C, Gibbs, S, de Jager, S C A, van Roon, J A G, Radstake, T R D J & Marut, W 2022, ' CXCL4 drives fibrosis by promoting several key cellular and molecular processes ', Cell Reports, vol. 38, no. 1, 110189 . https://doi.org/10.1016/j.celrep.2021.110189
Affandi, A J, Carvalheiro, T, Ottria, A, de Haan, J J, Brans, M A D, Brandt, M M, Tieland, R G, Lopes, A P, Fernandez, B M, Bekker, C P J, van der Linden, M, Zimmermann, M, Giovannone, B, Wichers, C G K, Garcia, S, de Kok, M, Stifano, G, Xu, Y J, Kowalska, M A, Waasdorp, M, Cheng, C, Gibbs, S, de Jager, S C A, van Roon, J A G, Radstake, T R D J & Marut, W 2022, ' CXCL4 drives fibrosis by promoting several key cellular and molecular processes ', Cell Reports, vol. 38, no. 1, 110189 . https://doi.org/10.1016/j.celrep.2021.110189
Cell Reports, 38(1). Cell Press
Affandi, A J, Carvalheiro, T, Ottria, A, de Haan, J J, Brans, M A D, Brandt, M M, Tieland, R G, Lopes, A P, Fernández, B M, Bekker, C P J, van der Linden, M, Zimmermann, M, Giovannone, B, Wichers, C G K, Garcia, S, de Kok, M, Stifano, G, Xu, Y J, Kowalska, M A, Waasdorp, M, Cheng, C, Gibbs, S, de Jager, S C A, van Roon, J A G, Radstake, T R D J & Marut, W 2022, ' CXCL4 drives fibrosis by promoting several key cellular and molecular processes ', Cell Reports, vol. 38, no. 1, 110189 . https://doi.org/10.1016/j.celrep.2021.110189
Fibrosis is a major cause of mortality worldwide, characterized by myofibroblast activation and excessive extracellular matrix deposition. Systemic sclerosis is a prototypic fibrotic disease in which CXCL4 is increased and strongly correlates with sk
Autor:
Eleni Chouri, Timothy R D J Radstake, Tiago Carvalheiro, Lara Bossini-Castillo, Andrea Ottria, Ralph G. Tieland, Samuel Garcia, Javier Martin, Lenny van Bon, Jorre S. Mertens, Marzia Rossato, Laurie M. G. de Kroon, Alsya J. Affandi, Romy B. Christmann, Jasper C A Broen, Joel A G van Roon, Wioleta Marut, Aridaman Pandit
Publikováno v:
Annals of the Rheumatic Diseases, 78, 9, pp. 1249-1259
Annals of the Rheumatic Diseases, 78, 1249-1259
Digital.CSIC. Repositorio Institucional del CSIC
instname
Annals of the Rheumatic Diseases, 78, 1249-1259
Digital.CSIC. Repositorio Institucional del CSIC
instname
Objectives: Systemic sclerosis (SSc) is an autoimmune disease with unknown pathogenesis manifested by inflammation, vasculopathy and fibrosis in skin and internal organs. Type I interferon signature found in SSc propelled us to study plasmacytoid den
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03f873556ac961d4a604867b154be246
https://hdl.handle.net/2066/208664
https://hdl.handle.net/2066/208664