Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Andrea Osterlehner"'
Autor:
Niels Bauer, Benedikt Oswald, Maximilian Eiche, Lisa Schiller, Emma Langguth, Christian Schantz, Andrea Osterlehner, Amy Shen, Shahram Misaghi, Julian Stingele, Simon Ausländer
Publikováno v:
Synthetic Biology. 7
Complex therapeutic antibody formats, such as bispecifics (bsAbs) or cytokine fusions, may provide new treatment options in diverse disease areas. However, the manufacturing yield of these complex antibody formats in Chinese Hamster Ovary (CHO) cells
Publikováno v:
Biotechnology and Bioengineering. 108:2670-2681
Mammalian cell lines for recombinant protein production need to maintain productivity over extended cultivation times. Long-term stability studies are time and resource intensive, but are widely performed to identify and eliminate unstable candidates
Autor:
Markus Wagner, Zsolt Ruzsics, Ulrich H. Koszinowski, Hans-Gerhard Burgert, Andrea Osterlehner, Jonathan P. Cook
Publikováno v:
Journal of virology. 80(16)
Until recently, adenovirus (Ad)-mediated gene therapy was almost exclusively based on human Ad type 5 (Ad5). Preexisting immunity and the limited, coxsackievirus and adenovirus receptor-dependent tropism of Ad5 stimulated attempts to exploit the natu