Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Andrea Osswald"'
Autor:
Leah T. Braun, Andrea Osswald, Stephanie Zopp, German Rubinstein, Frederick Vogel, Anna Riester, Jürgen Honegger, Graeme Eisenhofer, Georgiana Constantinescu, Timo Deutschbein, Marcus Quinkler, Ulf Elbelt, Heike Künzel, Hanna F. Nowotny, Nicole Reisch, Michaela F. Hartmann, Felix Beuschlein, Jörn Pons-Kühnemann, Martin Reincke, Stefan A. Wudy
Publikováno v:
EBioMedicine, Vol 99, Iss , Pp 104907- (2024)
Summary: Background: Diagnosing Cushing’s syndrome (CS) is highly complex. As the diagnostic potential of urinary steroid metabolome analysis by gas chromatography-mass spectrometry (GC-MS) in combination with systems biology has not yet been fully
Externí odkaz:
https://doaj.org/article/150c72c68c42466f90f11b1e75850b6a
Autor:
Sharmilee Vetrivel, Mariangela Tamburello, Andrea Oßwald, Ru Zhang, Ali Khan, Sara Jung, Jessica E. Baker, William E. Rainey, Elisabeth Nowak, Barbara Altieri, Mario Detomas, Deepika Watts, Tracy Ann Williams, Ben Wielockx, Felix Beuschlein, Martin Reincke, Silviu Sbiera, Anna Riester
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
BackgroundWe performed a transcriptomic analysis of adrenal signaling pathways in various forms of endogenous Cushing’s syndrome (CS) to define areas of dysregulated and druggable targets.MethodologyNext-generation sequencing was performed on adren
Externí odkaz:
https://doaj.org/article/06a80babc7d747e8a08bb4d32b7074de
Autor:
Ru Zhang, German Rubinstein, Sharmilee Vetrivel, Sonja Kunz, Frederick Vogel, Lucas Bouys, Jérôme Bertherat, Matthias Kroiss, Sinan Deniz, Andrea Osswald, Thomas Knösel, Martin Bidlingmaier, Silviu Sbiera, Martin Reincke, Anna Riester
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
IntroductionAdrenal vein sampling (AVS) is not a routine procedure in patients with primary bilateral macronodular adrenocortical hyperplasia (PBMAH), but has been used to determine lateralization of cortisol secretion in order to guide decision of u
Externí odkaz:
https://doaj.org/article/994ccb581cd94259baf62f6dad60fe30
Autor:
Frederick Vogel, Leah Braun, German Rubinstein, Stephanie Zopp, Andrea Oßwald, Katharina Schilbach, Ralf Schmidmaier, Martin Bidlingmaier, Martin Reincke
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
ContextGlucocorticoid excess exhibits multiple detrimental effects by its catabolic properties. Metformin was recently suggested to protect from adverse metabolic side-effects of glucocorticoid treatment. Whether metformin is beneficial in patients w
Externí odkaz:
https://doaj.org/article/f6d26f6a0b9b4cab90875caa115cdc18
Autor:
Sharmilee Vetrivel, Ru Zhang, Mareen Engel, Barbara Altieri, Leah Braun, Andrea Osswald, Martin Bidlingmaier, Martin Fassnacht, Felix Beuschlein, Martin Reincke, Alon Chen, Silviu Sbiera, Anna Riester
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
ContextCushing’s syndrome (CS) is a rare disease of endogenous hypercortisolism associated with high morbidity and mortality. Diagnosis and classification of CS is still challenging.ObjectiveCirculating microRNAs (miRNAs) are minimally invasive dia
Externí odkaz:
https://doaj.org/article/3971a63ac61345cf99516aa6e4c85f94
Autor:
Leah T. Braun, Anna Riester, Andrea Oßwald-Kopp, Julia Fazel, German Rubinstein, Martin Bidlingmaier, Felix Beuschlein, Martin Reincke
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Cushing's syndrome (CS) is a classical rare disease: it is often suspected in patients who do not have the disease; at the same time, it takes a mean of 3 years to diagnose CS in affected individuals. The main reason is the extreme rarity (1–3/mill
Externí odkaz:
https://doaj.org/article/80b10d0de0b743e487257c8d9fe005ba
Autor:
Lara Feldkamp, Lisa Müller, Timo Deutschbein, Mario Detomas, Stefanie Hahner, Christian J Strasburger, Heike Künzel, Andrea Oßwald, Leah Braun, German Rubinstein, Martin Reincke, Marcus Quinkler, Tina Kienitz
Publikováno v:
European Journal of Endocrinology. 188:366-374
Context Patients with endogenous Cushing's syndrome (CS) may suffer from a wide range of neuropsychiatric symptoms leading to impaired quality of life (QoL). Objective Glucocorticoid receptor (GR) polymorphisms are associated with increased (BclI and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59ddead2e9ece719f91ab751b0226162
https://doi.org/10.1093/ejendo/lvad043
https://doi.org/10.1093/ejendo/lvad043
Autor:
Sharmilee Vetrivel, Ru Zhang, Mareen Engel, Andrea Oßwald, Deepika Watts, Alon Chen, Ben Wielockx, Silviu Sbiera, Martin Reincke, Anna Riester
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 14; Pages: 7676
MiRNAs are important epigenetic players with tissue- and disease-specific effects. In this study, our aim was to investigate the putative differential expression of miRNAs in adrenal tissues from different forms of Cushing’s syndrome (CS). For this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b63a518f0ce0ffc8ca4eae7a18ef2c4
https://pubmed.ncbi.nlm.nih.gov/35887024
https://pubmed.ncbi.nlm.nih.gov/35887024
Autor:
Sharmilee Vetrivel, Ru Zhang, Ali Khan, Andrea Osswald, Martin Reincke, Silviu Sbieria, Anna Riester
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0973992c67909eafbdc9e9f2a202ceb1
https://doi.org/10.1530/endoabs.81.p272
https://doi.org/10.1530/endoabs.81.p272
Autor:
Ru Zhang, Sharmilee Vetrivel, Deepika Watts, Andrea Osswald, Mareen Engel, Felix Beuschlein, Alon Chen, Silviu Sbiera, Ben Wielockx, Martin Reincke, Anna Riester
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::053de6cc0ff63e1a57f36b629cab1fe8
https://doi.org/10.1530/endoabs.81.p20
https://doi.org/10.1530/endoabs.81.p20