Structural, Biophysical, and Computational Studies of a Murine Light Chain Dimer

Autor: Ricardo H. Arriaza, A. Brenda Kapingidza, Coleman Dolamore, Kriti Khatri, Andrea O’Malley, Jill Glesner, Sabina Wuenschmann, Noah P. Hyduke, William Easley, Charline Chhiv, Anna Pomés, Maksymilian Chruszcz

Publikováno v: Molecules, Vol 29, Iss 12, p 2885 (2024)

Antibodies are widely used in medicinal and scientific research due to their ability to bind to a specific antigen. Most often, antibodies are composed of heavy and light chain domains. Under physiological conditions, light chains are produced in exc

Externí odkaz: https://doaj.org/article/cfd640cde899426c8cf826e5a55bde2e

Purification, Characterization, and Structural Studies of a Sulfatase from Pedobacter yulinensis

Autor: Caleb R. Schlachter, Andrea O’Malley, Linda L. Grimes, John J. Tomashek, Maksymilian Chruszcz, L. Andrew Lee

Publikováno v: Molecules, Vol 27, Iss 1, p 87 (2021)

Sulfatases are ubiquitous enzymes that hydrolyze sulfate from sulfated organic substrates such as carbohydrates, steroids, and flavones. These enzymes can be exploited in the field of biotechnology to analyze sulfated metabolites in humans, such as s

Externí odkaz: https://doaj.org/article/9da0830bce6a4649abeb955e4a864929

Current status of structural studies of proteins originating from Arachnida

Autor: Safaa Kader, Ricardo H. Arriaza, Kriti Khatri, Andrea O’Malley, Vojislava Grbic, Miodrag Grbic, Maksymilian Chruszcz

Publikováno v: Systematic and Applied Acarology.

Arthropods from class Arachnida constitute a large and diverse group with over 100,000 described species, and they are sources of many proteins that have a direct impact on human health. Despite the importance of Arachnida, few proteins originating f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b783f0800f1d5792f7139198a28a1ff3
https://doi.org/10.11158/saa.28.2.12

Evaluation of the theoretical risk of cross-reactivity among recently identified food allergens for dogs

Autor: Thierry Olivry, Andrea O'Malley, Maksymilian Chruszcz

Publikováno v: Veterinary dermatology. 33(6)

There is increasing evidence of cross-reactivity between allergens of close or distant species. The A-RISC (Allergens'-Relative Identity, Similarity and Cross-reactivity) index helps evaluate the risk of theoretical cross-reactivity between proteins

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df2723b438765bd6778e592b8164f34d
https://pubmed.ncbi.nlm.nih.gov/36043337

Structural Characterization of Act c 10.0101 and Pun g 1.0101—Allergens from the Non-Specific Lipid Transfer Protein Family

Autor: Ivana Giangrieco, Maria Antonietta Ciardiello, Maksymilian Chruszcz, Andrea O’Malley, Lisa Tuppo, Anna Gawlicka-Chruszcz, S.S. Pote, Krzysztof Kowal

Publikováno v: Molecules, Vol 26, Iss 256, p 256 (2021)
Molecules
Volume 26
Issue 2
Molecules (Basel, Online) 26 (2021): 256. doi:10.3390/molecules26020256
info:cnr-pdr/source/autori:O'malley A.; Pote S.; Giangrieco I.; Tuppo L.; Gawlicka-Chruszcz A.; Kowal K.; Ciardiello M.A.; Chruszcz M./titolo:Structural characterization of act c 10.0101 and pun g 1.0101--allergens from the non-specific lipid transfer protein family/doi:10.3390%2Fmolecules26020256/rivista:Molecules (Basel, Online)/anno:2021/pagina_da:256/pagina_a:/intervallo_pagine:256/volume:26

Non-specific lipid transfer proteins (nsLTPs), which belong to the prolamin superfamily, are potent allergens. While the biological role of LTPs is still not well understood, it is known that these proteins bind lipids. Allergen nsLTPs are characteri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0b2cec27ec2e9fed4f640ff89ba8109
https://doi.org/10.3390/molecules26020256