MILD JUVENILE STRESS INCREASES RESILIENCE TO THE DEVELOPMENT OF ANXIOUS BEHAVIORS AND PREVENTS NEUROGENIC REDUCTION AFTER STRESS EXPOSURE IN ADULTHOOD

Autor: Patricia Chaves Peña, María Inmaculada Infantes López, José Muñoz Martín, Andrea Nieto Quero, Emma Zambrana Infantes, Margarita Pérez Martín, Carmen Pedraza

Publikováno v: IBRO Neuroscience Reports, Vol 15, Iss , Pp S913- (2023)

Externí odkaz: https://doaj.org/article/290c355c2214440abc2609e7a8a81974

Effects of the LPA1 Receptor Deficiency and Stress on the Hippocampal LPA Species in Mice

Autor: Sara Tabbai, Román Dario Moreno-Fernández, Emma Zambrana-Infantes, Andrea Nieto-Quero, Jerold Chun, Maria García-Fernández, Guillermo Estivill-Torrús, Fernando Rodríguez de Fonseca, Luis Javier Santín, Tiago Gil Oliveira, Margarita Pérez-Martín, Carmen Pedraza

Publikováno v: Frontiers in Molecular Neuroscience, Vol 12 (2019)

Lysophosphatidic acid (LPA) is an important bioactive lipid species that functions in intracellular signaling through six characterized G protein-coupled receptors (LPA1-6). Among these receptors, LPA1 is a strong candidate to mediate the central eff

Externí odkaz: https://doaj.org/article/7732bfc40743425f94110aeca12e1b63

Do changes in microglial status underlie neurogenesis impairments and depressive-like behaviours induced by psychological stress? A systematic review in animal models

Autor: Carmen Pedraza, Margarita Pérez-Martín, Patricia Chaves-Peña, Luis J. Santín, Andrea Nieto-Quero

Publikováno v: Neurobiology of Stress
Neurobiology of Stress, Vol 15, Iss, Pp 100356-(2021)
RIUMA. Repositorio Institucional de la Universidad de Málaga
instname

Stress may have a negative effect on mental health and is the primary environmental risk factor in the aetiology of depression. Nevertheless, the neurobiological mechanisms underlying this mood disorder remain poorly characterized. The hippocampus is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b1aeb832b336f6cfe5a20131a82754a
https://pubmed.ncbi.nlm.nih.gov/34355047

Effects of genetic deletion versus pharmacological blockade of the LPA1 receptor on depression-like behaviour and related brain functional activity

Autor: Francisco Javier Gómez-Salas, Guillermo Estivill-Torrús, Román D. Moreno-Fernández, Fernando Rodríguez de Fonseca, Andrea Nieto-Quero, Margarita Pérez-Martín, Luis J. Santín, Jerold Chun, Carmen Pedraza

Publikováno v: Disease Models & Mechanisms, Vol 11, Iss 9 (2018)

Animal models of psychopathology are particularly useful for studying the neurobiology of depression and characterising the subtypes. Recently, our group was the first to identify a possible relationship between the LPA1 receptor and a mixed anxiety-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08f129e1bff55df623af6a6869326f99
https://hdl.handle.net/10668/12776

New insights into hypothalamic neurogenesis disruption after acute and intense stress: implications for microglia and inflammation

Autor: María Inmaculada Infantes-López, Andrea Nieto-Quero, Patricia Chaves-Peña, Emma Zambrana-Infantes, Manuel Cifuentes, Javier Márquez, Carmen Pedraza, Margarita Pérez-Martín

Publikováno v: Frontiers in Neuroscience, Vol 17 (2023)

In recent years, the hypothalamus has emerged as a new neurogenic area, capable of generating new neurons after development. Neurogenesis-dependent neuroplasticity seems to be critical to continuously adapt to internal and environmental changes. Stre

Externí odkaz: https://doaj.org/article/b3b9af7504404419a7741b17aa9cc5d2