Zobrazeno 1 - 10
of 183
pro vyhledávání: '"Andrea Modesti"'
Autor:
Roberto Bei, Monica Benvenuto, Chiara Focaccetti, Sara Fazi, Marta Moretti, Daniela Nardozi, Valentina Angiolini, Sara Ciuffa, Loredana Cifaldi, Raffaele Carrano, Camilla Palumbo, Martino Tony Miele, Riccardo Bei, Giovanni Barillari, Vittorio Manzari, Enrico De Smaele, Andrea Modesti, Laura Masuelli
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-20 (2022)
Abstract Malignant mesothelioma (MM) is a rare orphan aggressive neoplasia with low survival rates. Among the other signaling pathways, ErbB receptors and Hh signaling are deregulated in MM. Thus, molecules involved in these signaling pathways could
Externí odkaz:
https://doaj.org/article/1e16b0cd67584040a68ba77a8a61a781
Autor:
Giuseppe Bellelli, Sergio Bernasconi, Gianni Bona, Mario Clerici, Giuseppe De Benedittis, Marco Del Prete, Fabio Esposito, Vassilios Fanos, Alessandro Genazzani, Paolo Inghilleri, Davide Lauro, Jeanette Maier, Stefano Masiero, Marco Matucci Cerinic, Alberto Migliore, Emilio Minelli, Andrea Modesti, Claudio Molinari, Valter Santilli, Umberto Solimene
Publikováno v:
Journal of Pediatric and Neonatal Individualized Medicine, Vol 11, Iss 2, Pp e110240-e110240 (2022)
During the Symposium “Systems Medicine. Integration models in clinical practice and new therapeutic solutions”, "The Milan Declaration 2022 – New goals for Medicine" – which outlines the current and future social and health scenarios that mak
Externí odkaz:
https://doaj.org/article/fcb3aea1ff624cb391fa83f0cb268ba2
Autor:
Monica Benvenuto, Sara Ciuffa, Chiara Focaccetti, Diego Sbardella, Sara Fazi, Manuel Scimeca, Grazia Raffaella Tundo, Giovanni Barillari, Maria Segni, Elena Bonanno, Vittorio Manzari, Andrea Modesti, Laura Masuelli, Massimo Coletta, Roberto Bei
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-23 (2021)
Abstract Head and neck cancer (HNC) has frequently an aggressive course for the development of resistance to standard chemotherapy. Thus, the use of innovative therapeutic drugs is being assessed. Bortezomib is a proteasome inhibitor with anticancer
Externí odkaz:
https://doaj.org/article/fb341c343f084ed79de8be99b14fac49
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 24, p 13543 (2021)
Wound healing requires static epithelial cells to gradually assume a mobile phenotype through a multi-step process termed epithelial-to-mesenchymal transition (EMT). Although it is inherently transient and reversible, EMT perdures and is abnormally a
Externí odkaz:
https://doaj.org/article/cb6eab2859b7447ba07e8e341f95b67a
Autor:
Monica Benvenuto, Rosanna Mattera, Joshua Ismaele Sticca, Piero Rossi, Chiara Cipriani, Maria Gabriella Giganti, Antonio Volpi, Andrea Modesti, Laura Masuelli, Roberto Bei
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Malignant mesothelioma (MM) is a primary tumor arising from mesothelial cells. The survival of MM patients following traditional chemotherapy is poor, thus innovative treatments for MM are needed. (-)-gossypol (AT-101) is a BH3 mimetic compound which
Externí odkaz:
https://doaj.org/article/04d6a7ce9de94a61bce09e3a496d5297
Autor:
Monica Benvenuto, Loredana Albonici, Chiara Focaccetti, Sara Ciuffa, Sara Fazi, Loredana Cifaldi, Martino Tony Miele, Fernando De Maio, Ilaria Tresoldi, Vittorio Manzari, Andrea Modesti, Laura Masuelli, Roberto Bei
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 18, p 6635 (2020)
One of the hallmarks of cellular transformation is the altered mechanism of cell death. There are three main types of cell death, characterized by different morphological and biochemical features, namely apoptosis (type I), autophagic cell death (typ
Externí odkaz:
https://doaj.org/article/5212086bdf674c70b84dba7414319a06
Autor:
Chiara Focaccetti, Monica Benvenuto, Sara Ciuffa, Sara Fazi, Manuel Scimeca, Alessandra Nardi, Martino Tony Miele, Andrea Battisti, Elena Bonanno, Andrea Modesti, Laura Masuelli, Roberto Bei
Publikováno v:
Nutrients, Vol 12, Iss 5, p 1417 (2020)
The survival rate for head and neck cancer patients has not substantially changed in the last two decades. We previously showed that two rV-neuT intratumoral injections induced an efficient antitumor response and rejection of transplanted Neu (rat Er
Externí odkaz:
https://doaj.org/article/be953dcd15284a2997bf38d6b288a761
Autor:
Massimo Fantini, Monica Benvenuto, Laura Masuelli, Giovanni Vanni Frajese, Ilaria Tresoldi, Andrea Modesti, Roberto Bei
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 5, Pp 9236-9282 (2015)
Carcinogenesis is a multistep process triggered by genetic alterations that activate different signal transduction pathways and cause the progressive transformation of a normal cell into a cancer cell. Polyphenols, compounds ubiquitously expressed in
Externí odkaz:
https://doaj.org/article/74324603045b40cab78006d121903161
Autor:
Laura Masuelli, Monica Benvenuto, Rosanna Mattera, Enrica Di Stefano, Erika Zago, Gloria Taffera, Ilaria Tresoldi, Maria Gabriella Giganti, Giovanni Vanni Frajese, Ginevra Berardi, Andrea Modesti, Roberto Bei
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Malignant mesothelioma (MM) is a tumor arising from mesothelium. MM patients’ survival is poor. The polyphenol 4′,5,7,-trihydroxyflavone Apigenin (API) is a “multifunctional drug”. Several studies have demonstrated API anti-tumoral effects. H
Externí odkaz:
https://doaj.org/article/aa4def43874c42aa8727ac7ced11aa5f
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 12, p 2970 (2019)
The sharing of molecules function that affects both tumor growth and neoangiogenesis with cells of the immune system creates a mutual interplay that impairs the host’s immune response against tumor progression. Increasing evidence shows that tumors
Externí odkaz:
https://doaj.org/article/e3b3d1b9ca3c41bea8e52af9358907f9