Epigenetics and Communication Mechanisms in Microglia Activation with a View on Technological Approaches

Autor: Sabrina Petralla, Francesca De Chirico, Andrea Miti, Ottavia Tartagni, Francesca Massenzio, Eleonora Poeta, Marco Virgili, Giampaolo Zuccheri, Barbara Monti

Publikováno v: Biomolecules, Vol 11, Iss 2, p 306 (2021)

Microglial cells, the immune cells of the central nervous system (CNS), play a crucial role for the proper brain development and function and in CNS homeostasis. While in physiological conditions, microglia continuously check the state of brain paren

Externí odkaz: https://doaj.org/article/e01e4a8c1a47412d8f9067f0ce22bf69

Epigenetics and Communication Mechanisms in Microglia Activation with a View on Technological Approaches

Autor: Andrea Miti, Ottavia Tartagni, Marco Virgili, Francesca De Chirico, Sabrina Petralla, Eleonora Poeta, Francesca Massenzio, Giampaolo Zuccheri, Barbara Monti

Publikováno v: Biomolecules, Vol 11, Iss 306, p 306 (2021)
Biomolecules 11 (2021): 1–29. doi:10.3390/biom11020306
info:cnr-pdr/source/autori:Petralla S.; De Chirico F.; Miti A.; Tartagni O.; Massenzio F.; Poeta E.; Virgili M.; Zuccheri G.; Monti B./titolo:Epigenetics and communication mechanisms in microglia activation with a view on technological approaches/doi:10.3390%2Fbiom11020306/rivista:Biomolecules/anno:2021/pagina_da:1/pagina_a:29/intervallo_pagine:1–29/volume:11
Biomolecules

Microglial cells, the immune cells of the central nervous system (CNS), play a crucial role for the proper brain development and function and in CNS homeostasis. While in physiological conditions, microglia continuously check the state of brain paren

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a237a6e747d5715129427542bcf5e063
https://www.mdpi.com/2218-273X/11/2/306

A miRNA biosensor based on localized surface plasmon resonance enhanced by surface-bound hybridization chain reaction

Autor: Andrea Miti, Sophie Thamm, Wolfgang Fritzsche, Philipp Müller, Giampaolo Zuccheri, Andrea Csáki

Publikováno v: Biosensors & Bioelectronics

The dysregulation of the concentration of individual circulating microRNAs or small sets of them has been recognized as a marker of disease. For example, an increase of the concentration of circulating miR-17 has been linked to lung cancer and metast

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d4b06daf93c2fbb6472d825d9850374
https://pubmed.ncbi.nlm.nih.gov/32798803

Tau-Centric Multitarget Approach for Alzheimer's Disease: Development of First-in-Class Dual Glycogen Synthase Kinase 3β and Tau-Aggregation Inhibitors

Autor: Loreto Martínez-González, Martina Rossi, Concepción Pérez, Maria Laura Bolognesi, Giampaolo Zuccheri, Daniele Tedesco, Josefa Zaldivar-Diez, Nuria E. Campillo, Manuela Bartolini, Alessandra Feoli, Giuseppe Legname, Barbara Monti, Sabrina Petralla, Fabio Moda, Annachiara Gandini, Carlos Roca, Sabrina Castellano, Ana Martínez, Andrea Miti

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname

Several findings propose the altered tau protein network as an important target for Alzheimer's disease (AD). Particularly, two points of pharmacological intervention can be envisaged: inhibition of phosphorylating tau kinase GSK-3β and tau aggregat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e47af3c99fb1b218a293974584fd502d
https://pubmed.ncbi.nlm.nih.gov/30078314

A colorimetric assay of DNA methyltransferase activity based on peroxidase mimicking of DNA template Ag/Pt bimetallic nanoclusters

Autor: Saman Hosseinkhani, Morteza Hosseini, Giampaolo Zuccheri, Hanie Ahmadzade Kermani, Mehdi Dadmehr, Andrea Miti, Mohammad Reza Ganjali

DNA methylation catalyzed by DNA methyl transferase (MTase) is a significant epigenetic process for modulating gene expression. Abnormal levels of DNA MTase enzyme have been regarded as a cancer biomarker or a sign of bacterial diseases. We developed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e56c8032069237b2951648ef16b7c44
http://hdl.handle.net/11585/675177