Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Andrea Menegon"'
Autor:
Sabrina Giofrè, Antonio Renda, Silvia Sesana, Beatrice Formicola, Barbara Vergani, Biagio Eugenio Leone, Vanna Denti, Giuseppe Paglia, Serena Groppuso, Valentina Romeo, Luca Muzio, Andrea Balboni, Andrea Menegon, Antonia Antoniou, Arianna Amenta, Daniele Passarella, Pierfausto Seneci, Sara Pellegrino, Francesca Re
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2402 (2022)
Dual functionalized liposomes were developed to cross the blood–brain barrier (BBB) and to release their cargo in a pathological matrix metalloproteinase (MMP)-rich microenvironment. Liposomes were surface-functionalized with a modified peptide der
Externí odkaz:
https://doaj.org/article/c466099e0aa34384bb4a567dc44eff87
Autor:
Antonello Spinelli, Maria Girelli, Daniela Arosio, Laura Polito, Paola Podini, Gianvito Martino, Pierfausto Seneci, Luca Muzio, Andrea Menegon
Publikováno v:
Journal of Nanobiotechnology, Vol 17, Iss 1, Pp 1-13 (2019)
Abstract Background The increasing use of gold nanoparticles (AuNPs) in the field of neuroscience instilled hope for their rapid translation to the clinical practice. AuNPs can be engineered to carry therapeutics or diagnostics in the diseased brain,
Externí odkaz:
https://doaj.org/article/f9a6b9b5521448cdbedd2d3ab02ad5f3
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83899 (2013)
It is known that cell density influences the maturation process of in vitro neuronal networks. Neuronal cultures plated with different cell densities differ in number of synapses per neuron and thus in single neuron synaptic transmission, which resul
Externí odkaz:
https://doaj.org/article/9281c933697e465bb122ac2713e614a3
Autor:
Silvia Cainarca, Simone Fenu, Cinzia Ferri, Cinzia Nucci, Patrizia Arioli, Andrea Menegon, Lorenzo Piemonti, Stefan Lohmer, Lawrence Wrabetz, Sabrina Corazza
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8882 (2010)
Exogenous expression of pharmacological targets in transformed cell lines has been the traditional platform for high throughput screening of small molecules. However, exogenous expression in these cells is limited by aberrant dosage, or its toxicity,
Externí odkaz:
https://doaj.org/article/537db1fbbfe2407e801923714b5d0056
Publikováno v:
Neuropharmacology. 148:366-376
Acid-sensing ion channels (ASICs) are proton-activated, sodium-permeable channels, highly expressed in both central and peripheral nervous systems. ASIC1a is the most abundant isoform in the central nervous system and is credited to be involved in se
Autor:
Giuseppe Pignataro, Anna Pannaccione, Lucio Annunziato, Antonio Vinciguerra, Erika Pizzi, Tiziana Petrozziello, Agnese Secondo, Stefania Ippati, Eloise Mastrangelo, Andrea Menegon, Pietro Randazzo, Stefano Barbini, Cecilia Caccavone, Mario Milani, Roselia Ciccone, Luca Muzio, Pierfausto Seneci, Davide Gornati, Eleonora Colombo, Amal Z. Hassan
Publikováno v:
Journal of medicinal chemistry (Online) 64 (2021): 8333–8353. doi:10.1021/acs.jmedchem.1c00305
info:cnr-pdr/source/autori:Gornati D.; Ciccone R.; Vinciguerra A.; Ippati S.; Pannaccione A.; Petrozziello T.; Pizzi E.; Hassan A.; Colombo E.; Barbini S.; Milani M.; Caccavone C.; Randazzo P.; Muzio L.; Annunziato L.; Menegon A.; Secondo A.; Mastrangelo E.; Pignataro G.; Seneci P./titolo:Synthesis and Characterization of Novel Mono-And Bis-Guanyl Hydrazones as Potent and Selective ASIC1 Inhibitors Able to Reduce Brain Ischemic Insult/doi:10.1021%2Facs.jmedchem.1c00305/rivista:Journal of medicinal chemistry (Online)/anno:2021/pagina_da:8333/pagina_a:8353/intervallo_pagine:8333–8353/volume:64
info:cnr-pdr/source/autori:Gornati D.; Ciccone R.; Vinciguerra A.; Ippati S.; Pannaccione A.; Petrozziello T.; Pizzi E.; Hassan A.; Colombo E.; Barbini S.; Milani M.; Caccavone C.; Randazzo P.; Muzio L.; Annunziato L.; Menegon A.; Secondo A.; Mastrangelo E.; Pignataro G.; Seneci P./titolo:Synthesis and Characterization of Novel Mono-And Bis-Guanyl Hydrazones as Potent and Selective ASIC1 Inhibitors Able to Reduce Brain Ischemic Insult/doi:10.1021%2Facs.jmedchem.1c00305/rivista:Journal of medicinal chemistry (Online)/anno:2021/pagina_da:8333/pagina_a:8353/intervallo_pagine:8333–8353/volume:64
Acid-sensitive ion channels (ASICs) are sodium channels partially permeable to Ca2+ ions, listed among putative targets in central nervous system (CNS) diseases in which a pH modification occurs. We targeted novel compounds able to modulate ASIC1 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e7c20a7c07be1a20f4dc57376a9ac3f
http://www.cnr.it/prodotto/i/458062
http://www.cnr.it/prodotto/i/458062
Autor:
Adolfo Prandi, Luca Ferrante, Maria Veneziano, Mariana Gallo, Marco Ferrara, Leda Ivanova Bencheva, Antonella Cellucci, Nausicaa Mazzocchi, Pierfausto Seneci, Silvano Ronzoni, Andrea Menegon, Roberta Sinisi, Pietro Randazzo, Vincenzo Summa, Marilenia De Matteo, Romano Di Fabio
[Image: see text] Acid-sensing ion channels (ASICs) are a family of ion channels permeable to cations and largely responsible for the onset of acid-evoked ion currents both in neurons and in different types of cancer cells, thus representing a potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c8a3bad6284485d88304e25bccd2e07
http://hdl.handle.net/11588/828238
http://hdl.handle.net/11588/828238
Autor:
Pierfausto Seneci, Daniela Arosio, Andrea Menegon, Laura Polito, Maria Girelli, Gianvito Martino, Paola Podini, Luca Muzio, Antonello E. Spinelli
Publikováno v:
Journal of nanobiotechnology 17 (2019). doi:10.1186/s12951-019-0481-3
info:cnr-pdr/source/autori:Spinelli, Antonello; Girelli, Maria; Arosio, Daniela; Polito, Laura; Podini, Paola; Martino, Gianvito; Seneci, Pierfausto; Muzio, Luca; Menegon, Andrea/titolo:Intracisternal delivery of PEG-coated gold nanoparticles results in high brain penetrance and long-lasting stability/doi:10.1186%2Fs12951-019-0481-3/rivista:Journal of nanobiotechnology/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume:17
Journal of Nanobiotechnology, Vol 17, Iss 1, Pp 1-13 (2019)
Journal of Nanobiotechnology
info:cnr-pdr/source/autori:Spinelli, Antonello; Girelli, Maria; Arosio, Daniela; Polito, Laura; Podini, Paola; Martino, Gianvito; Seneci, Pierfausto; Muzio, Luca; Menegon, Andrea/titolo:Intracisternal delivery of PEG-coated gold nanoparticles results in high brain penetrance and long-lasting stability/doi:10.1186%2Fs12951-019-0481-3/rivista:Journal of nanobiotechnology/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume:17
Journal of Nanobiotechnology, Vol 17, Iss 1, Pp 1-13 (2019)
Journal of Nanobiotechnology
Background The increasing use of gold nanoparticles (AuNPs) in the field of neuroscience instilled hope for their rapid translation to the clinical practice. AuNPs can be engineered to carry therapeutics or diagnostics in the diseased brain, possibly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87551a4f510615775fca32cd6034c1ba
Autor:
Giulia Regalia, Emilia Biffi, S. Achilli, Alessandra Pedrocchi, Giancarlo Ferrigno, Andrea Menegon
Publikováno v:
Biotechnology and Bioengineering. 113:403-413
Two binding requirements for in vitro studies on long-term neuronal networks dynamics are (i) finely controlled environmental conditions to keep neuronal cultures viable and provide reliable data for more than a few hours and (ii) parallel operation
Autor:
Francesco Morena, Silvia De Cicco, Vasco Meneghini, Andrea Menegon, Angela Gritti, Sabata Martino, Mirella Filocamo, Serena Grossi, Maria Blomqvist, Marcus Ståhlman, Marco Luciani, Giacomo Frati
Publikováno v:
Cell Death and Disease, Vol 9, Iss 6, Pp 1-15 (2018)
Cell death & disease 9(6), 698 (2018). doi:10.1038/s41419-018-0737-0
Cell Death & Disease
Cell death & disease 9(6), 698 (2018). doi:10.1038/s41419-018-0737-0
Cell Death & Disease
The pathological cascade leading from primary storage to neural cell dysfunction and death in metachromatic leukodystrophy (MLD) has been poorly elucidated in human-derived neural cell systems. In the present study, we have modeled the progression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd060b2fc1cff8f5f7298f1ba3013566
https://hdl.handle.net/11391/1441378
https://hdl.handle.net/11391/1441378