Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Andrea Mančíková"'
Autor:
Daniel Krsek, Daniel Alejandro Yara, Hana Hrbáčková, Ondřej Daniel, Andrea Mančíková, Stephanie Schüller, Martina Bielaszewska
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Outer membrane vesicles (OMVs) carrying virulence factors of enterohemorrhagic Escherichia coli (EHEC) are assumed to play a role in the pathogenesis of life-threatening hemolytic uremic syndrome (HUS). However, it is unknown if and how OMVs, which a
Externí odkaz:
https://doaj.org/article/b8a3c770a79141138cee6495e8de3f13
Autor:
Jiří Vávra, Andrea Mančíková, Kateřina Pavelcová, Lenka Hasíková, Jana Bohatá, Blanka Stibůrková
Publikováno v:
Cells, Vol 11, Iss 7, p 1063 (2022)
The OAT1 (SLC22A6) and OAT3 (SLC22A8) urate transporters are located on the basolateral membrane of the proximal renal tubules, where they ensure the uptake of uric acid from the urine back into the body. In a cohort of 150 Czech patients with primar
Externí odkaz:
https://doaj.org/article/51fca690f87947968790cbab6e029aaa
Autor:
Yu Toyoda, Andrea Mančíková, Vladimír Krylov, Keito Morimoto, Kateřina Pavelcová, Jana Bohatá, Karel Pavelka, Markéta Pavlíková, Hiroshi Suzuki, Hirotaka Matsuo, Tappei Takada, Blanka Stiburkova
Publikováno v:
Cells, Vol 8, Iss 4, p 363 (2019)
ATP-binding cassette subfamily G member 2 (ABCG2) is a physiologically important urate transporter. Accumulating evidence demonstrates that congenital dysfunction of ABCG2 is an important genetic risk factor in gout and hyperuricemia; recent studies
Externí odkaz:
https://doaj.org/article/0ef5118a69e3431d892c983e495532d9
Autor:
Blanka Stiburkova, Jana Bohata, Iveta Minarikova, Andrea Mancikova, Jiri Vavra, Vladimír Krylov, Zdenek Doležel
Publikováno v:
Applied Sciences, Vol 9, Iss 17, p 3479 (2019)
Renal hypouricemia (RHUC) is caused by an inherited defect in the main (reabsorptive) renal urate transporters, URAT1 and GLUT9. RHUC is characterized by decreased concentrations of serum uric acid and an increase in its excretion fraction. Patients
Externí odkaz:
https://doaj.org/article/c8fad83cc0eb48d29887ebc9e090eeaf
Autor:
Olha Hurba, Andrea Mancikova, Vladimir Krylov, Marketa Pavlikova, Karel Pavelka, Blanka Stibůrková
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107902 (2014)
ObjectiveUsing European descent Czech populations, we performed a study of SLC2A9 and SLC22A12 genes previously identified as being associated with serum uric acid concentrations and gout. This is the first study of the impact of non-synonymous allel
Externí odkaz:
https://doaj.org/article/9ac78a62ca254f5b8de05762a4e17dbe