Zobrazeno 1 - 10
of 610
pro vyhledávání: '"Andrea MAZZANTI"'
Autor:
Simone Scacchi, Luca F Pavarino, Andrea Mazzanti, Alessandro Trancuccio, Silvia G Priori, Piero Colli Franzone
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0305248 (2024)
Long QT Syndrome type 8 (LQT8) is a cardiac arrhythmic disorder associated with Timothy Syndrome, stemming from mutations in the CACNA1C gene, particularly the G406R mutation. While prior studies hint at CACNA1C mutations' role in ventricular arrhyth
Externí odkaz:
https://doaj.org/article/6c7cf98d4dcd4a5e885bcba15f2c67cd
Autor:
Eugenio Caradonna, MD, Elisabetta Mormone, PhD, Enrico Maria Centritto, MD, Andrea Mazzanti, MD, PhD, Stefano Papini, MD, Mara Fanelli, PhD, Lella Petrella, PhD, Arnolfo Petruzziello, MD, Michele Angelo Farina, MD, Eleonora Farina, MD, Bruno Amato, MD, Carlo Maria De Filippo, MD, Emilio Vanoli, MD
Publikováno v:
JVS - Vascular Science, Vol 4, Iss , Pp 100130- (2023)
Background: Bone marrow (BM)-derived stem cells were implanted to induce angiogenesis in patients with no-option critical limb-threatening ischemia. Considering the potential for this therapy, conflicting results related to BM harvesting methods have
Externí odkaz:
https://doaj.org/article/787f007a6a4444c3850cd3dae210f0cf
Autor:
Meng Wang, Derick R. Peterson, Eleonora Pagan, Vincenzo Bagnardi, Andrea Mazzanti, Scott McNitt, David Q. Rich, Christopher L. Seplaki, Valentina Kutyifa, Bronislava Polonsky, Alon Barsheshet, Deni Kukavica, Spencer Rosero, Ilan Goldenberg, Silvia Priori, Wojciech Zareba
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundRisk stratification in long QT syndrome (LQTS) patients is important for optimizing patient care and informing clinical decision making. We developed a risk prediction algorithm with prediction of 5-year absolute risk of the first life-thre
Externí odkaz:
https://doaj.org/article/2b5b9415f5234665941d3ddc22185c44
Autor:
Alessia Ciogli, Andrea Fochetti, Andrea Sorato, Giancarlo Fabrizi, Nunzio Matera, Andrea Mazzanti, Michele Mancinelli
Publikováno v:
Molecules, Vol 28, Iss 13, p 4915 (2023)
The dynamic scenario of di-aryls-pyrano-chromenes was investigated using DFT calculations. The symmetry of the chromene scaffold and the presence of two ortho-substituted aryls substituents can generate two syn/anti diastereoisomers and conformationa
Externí odkaz:
https://doaj.org/article/332d592586ac43f6a811ab04c5151923
Autor:
Simona Zanotti, Michela Ripolone, Laura Napoli, Daniele Velardo, Sabrina Salani, Patrizia Ciscato, Silvia Priori, Deni Kukavica, Andrea Mazzanti, Luca Diamanti, Elisa Vegezzi, Maurizio Moggio, Stefania Corti, Giacomo Comi, Monica Sciacco
Publikováno v:
Cells, Vol 12, Iss 10, p 1405 (2023)
Phospholamban is involved in the regulation of the activity and storage of calcium in cardiac muscle. Several mutations have been identified in the PLN gene causing cardiac disease associated with arrhythmogenic and dilated cardiomyopathy. The patho-
Externí odkaz:
https://doaj.org/article/397496b545584b0a8b6b636d79b659f7
Publikováno v:
Molecules, Vol 28, Iss 7, p 3176 (2023)
Atorvastatins play an important role in the inhibition of HMG-CoA reductase, an enzyme present in the liver that takes part in the biosynthesis of cholesterol. In this article, we report the total synthesis of a lactone–atorvastatin prodrug with ad
Externí odkaz:
https://doaj.org/article/cd9609afb6334a9ca2fef4ed93690371
Autor:
Andrea Mazzanti, Eva Arianna Aurelia Pogna, Lavinia Ghirardini, Michele Celebrano, Andrea Schirato, Giuseppe Marino, Aristide Lemaítre, Marco Finazzi, Costantino De Angelis, Giuseppe Leo, Giulio Cerullo, Giuseppe Della Valle
Publikováno v:
Small Science, Vol 1, Iss 7, Pp n/a-n/a (2021)
The transient optical response of multiresonant all‐dielectric nanoantennas via a combination of broadband ultrafast reflectivity experiments and nonlinear optics nanoscale modeling is studied. Ultrafast all‐optical control of the reflectivity is
Externí odkaz:
https://doaj.org/article/2a2ab89f24a740b5b9a14825f0c94fd4
Publikováno v:
ACS Omega, Vol 4, Iss 3, Pp 4712-4720 (2019)
Externí odkaz:
https://doaj.org/article/fd36a7bc68b4405ea211a9ec64d482a9
Autor:
Vittoria Di Mauro, Paola Ceriotti, Francesco Lodola, Nicolò Salvarani, Jessica Modica, Marie-Louise Bang, Andrea Mazzanti, Carlo Napolitano, Silvia G. Priori, Daniele Catalucci
Publikováno v:
Frontiers in Physiology, Vol 11 (2021)
Brugada syndrome (BrS) is an inherited arrhythmogenic disease that may lead to sudden cardiac death in young adults with structurally normal hearts. No pharmacological therapy is available for BrS patients. This situation highlights the urgent need t
Externí odkaz:
https://doaj.org/article/185089ae836f4f82a40fa10a9c2cfed3
Autor:
Jordi Cano, Esther Zorio, Andrea Mazzanti, Miguel Ángel Arnau, Beatriz Trenor, Silvia G. Priori, Javier Saiz, Lucia Romero
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
The prolongation of the QT interval represents the main feature of the long QT syndrome (LQTS), a life-threatening genetic disease. The heterozygous SCN5A V411M mutation of the human sodium channel leads to a LQTS type 3 with severe proarrhythmic eff
Externí odkaz:
https://doaj.org/article/ff65d0b4f8104354aaf734f3cddc1cf8