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pro vyhledávání: '"Andrea M. Clark"'
Autor:
Samjhana Pandey, Krishna K. Raut, Andrea M. Clark, Antoine Baudin, Lamya Djemri, David S. Libich, Komala Ponniah, Steven M. Pascal
Publikováno v:
Biomolecules, Vol 13, Iss 4, p 667 (2023)
Intrinsically disordered proteins play important roles in cell signaling, and dysregulation of these proteins is associated with several diseases. Prostate apoptosis response-4 (Par-4), an approximately 40 kilodalton proapoptotic tumor suppressor, is
Externí odkaz:
https://doaj.org/article/c707f3aca2e941eeb22bcb9cf238aaae
Autor:
Andrea M. Clark, Komala Ponniah, Meghan S. Warden, Emily M. Raitt, Andrea C. Yawn, Steven M. Pascal
Publikováno v:
Biomolecules, Vol 8, Iss 4, p 162 (2018)
Prostate apoptosis response-4 (Par-4) is a 38 kDa largely intrinsically disordered tumor suppressor protein that functions in cancer cell apoptosis. Par-4 down-regulation is often observed in cancer while up-regulation is characteristic of neurodegen
Externí odkaz:
https://doaj.org/article/d52247bf479e4f079f1ccd16ffa880b9
Autor:
Andrea M. Clark, Benjamin G. Smith, Komala Ponniah, Emily M. Raitt, Steven M. Pascal, Meghan S. Warden
Publikováno v:
The FEBS Journal. 286:4060-4073
The prostate apoptosis response-4 (Par-4) tumor suppressor can selectively kill cancer cells via apoptosis while leaving healthy cells unharmed. Full length Par-4 has been shown to be predominantly intrinsically disordered in vitro under neutral cond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01db6e98e990fe79550991e7b41b6bb7
https://doi.org/10.1111/febs.14955
https://doi.org/10.1111/febs.14955