Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Andrea M Macedo"'
Autor:
Margoth Moreno, Daniella A D'ávila, Marcelo N Silva, Lúcia MC Galvão, Andrea M Macedo, Egler Chiari, Eliane D Gontijo, Bianca Zingales
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 105, Iss 7, Pp 918-924 (2010)
Therapeutic failure of benznidazole (BZ) is widely documented in Chagas disease and has been primarily associated with variations in the drug susceptibility of Trypanosoma cruzi strains. In humans, therapeutic success has been assessed by the negativ
Externí odkaz:
https://doaj.org/article/bed692bc0c74440f9f7a2a1468986aec
Autor:
Luciana O Andrade, Lúcia MC Galvão, Maria de Nazareth SL Meirelles, Egler Chiari, Sergio DJ Pena, Andrea M Macedo
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 105, Iss 6, Pp 834-837 (2010)
We have previously demonstrated selection favoring the JG strain of Trypanosoma cruziin hearts of BALB/c mice that were chronically infected with an equal mixture of the monoclonal JG strain and a clone of the Colombian strain, Col1.7G2. To evaluate
Externí odkaz:
https://doaj.org/article/562c0830760a4d7db2ad42bd057e7f74
Autor:
Pedro H N Aguiar, Carolina Furtado, Bruno M Repolês, Grazielle A Ribeiro, Isabela C Mendes, Eduardo F Peloso, Fernanda R Gadelha, Andrea M Macedo, Glória R Franco, Sérgio D J Pena, Santuza M R Teixeira, Leda Q Vieira, Alessandra A Guarneri, Luciana O Andrade, Carlos R Machado
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 6, p e2279 (2013)
The main consequence of oxidative stress is the formation of DNA lesions, which can result in genomic instability and lead to cell death. Guanine is the base that is most susceptible to oxidation, due to its low redox potential, and 8-oxoguanine (8-o
Externí odkaz:
https://doaj.org/article/c3030a2328674338ab1d1c9ce0656a09
Autor:
Jorge M Freitas, Luciana O Andrade, Simone F Pires, Ricardo Lima, Egler Chiari, Ricardo R Santos, Milena Soares, Carlos R Machado, Gloria R Franco, Sergio D J Pena, Andrea M Macedo
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5113 (2009)
We have previously demonstrated that both parasite genetic variability and host genetic background were important in determining the differential tissue distribution of the Col1.7G2 and JG T. cruzi monoclonal strains after artificial infections in mi
Externí odkaz:
https://doaj.org/article/f37398b19dfe459a97b4b454a8523fe9
Autor:
Adriana Araújo Dutra Rodrigues, Andrea M. Macedo, Giordanna Camilla Bié de Oliveira, Lucas Passos Barreto, Eduardo Fleury Mortimer, Laila Thayanne Gomes de Almeida, Ana Luiza de Quadros, Matheus Augusto Campelo Felix, Penha Souza Silva
Publikováno v:
Research in Science Education. 51:135-152
This research draws on Legitimation Code Theory (LCT) to understand the epistemic dimension of the higher education classroom discourse of a professor who is well evaluated by his students. In expository science classroom discourse, concepts are load
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::226218647642699b837eec77757d46e0
https://doi.org/10.1007/s11165-020-09969-z
https://doi.org/10.1007/s11165-020-09969-z
Autor:
Daniela de Laet Souza, Helaine Graziele Santos Vieira, Andrea M. Macedo, Daniela Ferreira Chame, Carlos Renato Machado, Erich Birelli Tahara, Glória Regina Franco
Publikováno v:
Parasitology Research. 119:749-753
Trypanosoma cruzi, the causative agent of Chagas disease, has a complex life cycle that requires the adaptation to different environments. In the absence of traditional mechanisms for regulation of gene expression, this parasite relies on posttranscr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31eec8c669f2880b48bf8874beb400b5
https://doi.org/10.1007/s00436-019-06554-w
https://doi.org/10.1007/s00436-019-06554-w
Autor:
Andréia Laura Prates Rodrigues, Ana Paula Moreira Franco Luiz, Jader S. Cruz, Andrea M. Macedo, Paula Rhana
Publikováno v:
Brazilian Journal of Development, Vol 5, Iss 7, Pp 10770-10778 (2019)
De maneira geral, o estudo de bioquímica é complexo e abstrato, em que a quantidade de informações e a apresentação das vias metabólicas geralmente assustam o aluno, resultando muitas vezes na perda de interesse e inadequada compreensão do co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19179ea3b5a2953efb075acf2b7798b9
https://doi.org/10.34117/bjdv5n7-214
https://doi.org/10.34117/bjdv5n7-214
Autor:
Andrea M. Macedo, Maria Carolina Elias, Stenio Perdigão Fragoso, Marcelo Santos da Silva, Glória Regina Franco, Carlos Renato Machado, Erich Birelli Tahara, Luiz R. O. Tosi, Bruno Carvalho Resende, Stela Virgilio, Luciana O. Andrade, Héllida Marina Costa-Silva, João Luís Reis-Cunha, Sérgio Danilo Junho Pena, Adriana Castilhos Souza Umaki, Willian Prado
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
DNA topoisomerases are enzymes that modulate DNA topology. Among them, topoisomerase 3α is engaged in genomic maintenance acting in DNA replication termination, sister chromatid separation, and dissolution of recombination intermediates. To evaluate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a091a04b23543843c740d105c5c9002
https://doi.org/10.3389/fcell.2021.633195
https://doi.org/10.3389/fcell.2021.633195
Autor:
Carlos Renato Machado, Andrea M. Macedo, Eric Birelli Tahara, Mariana Boroni, Daniela Ferreira Chame, Glória Regina Franco, Sérgio Danilo Junho Pena, Nayara Evelin de Toledo, Egler Chiari, Daniela de Laet Souza, Tiago B. R. Castro, Maria Cecilia Campos Canesso
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Frontiers in Genetics
Frontiers in Genetics
The protozoanTrypanosoma cruzi(T. cruzi) is a well-adapted parasite to mammalian hosts and the pathogen of Chagas disease in humans. As both host andT. cruziare highly genetically diverse, many variables come into play during infection, making diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c45b4685b7ee690d2adde847b6c8581e
https://www.frontiersin.org/article/10.3389/fgene.2020.01031/full
https://www.frontiersin.org/article/10.3389/fgene.2020.01031/full
Autor:
Bruno Carvalho Resende, Sérgio Danilo Junho Pena, Anna Carolina Paganini Guañabens, Luciana O. Andrade, Verônica Santana, Bruno Marçal Repolês, Stenio Perdigão Fragoso, Erich Birelli Tahara, Anny Carolline Silva Oliveira, Andrea M. Macedo, Carlos Renato Machado, Priscila Mazzochi Hiraiwa, Glória Regina Franco
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Frontiers in Cellular and Infection Microbiology
Frontiers in Cellular and Infection Microbiology
The protozoan Trypanosoma cruzi is the causative agent of Chagas disease, a neglected tropical disease that affects around 8 million people worldwide. Chagas disease can be divided into two stages: an acute stage with high parasitemia followed by a l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5b589dbe4727c69d7ec19f41d2d326a
https://www.frontiersin.org/article/10.3389/fcimb.2020.00005/full
https://www.frontiersin.org/article/10.3389/fcimb.2020.00005/full