Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Andrea M, Werneke"'
Autor:
Michael E. Berens, Seungchan Kim, Andrea M. Werneke, Marni B. Siegel, Jeremy M. Simon, Irvin Dm, Robert S. McNeill, Mark Vitucci, Miller Cr, Harshil Dhruv, Ralf S. Schmid, Ryan E. Bash
Publikováno v:
Neuro-Oncology. 19:1237-1247
Background Gliomas are diverse neoplasms with multiple molecular subtypes. How tumor-initiating mutations relate to molecular subtypes as these tumors evolve during malignant progression remains unclear. Methods We used genetically engineered mouse m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d912d54ae4a172cee95678cbbb8f622
https://doi.org/10.1093/neuonc/nox050
https://doi.org/10.1093/neuonc/nox050
Autor:
Andrea M. Werneke, Jeremy M. Simon, Jing Wu, Matthew G. Ewend, Ralf S. Schmid, Ryan E. Bash, Kristen K. White, Lauren Huey, Robert S. McNeill, C. Ryan Miller, Mark Vitucci
Background Glioma stem cells (GSCs) from human glioblastomas (GBMs) are resistant to radiation and chemotherapy and may drive recurrence. Treatment efficacy may depend on GSCs, expression of DNA repair enzymes such as methylguanine methyltransferase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2619b8bb1b0aa6746cd7dc63ffb9650
https://europepmc.org/articles/PMC4896545/
https://europepmc.org/articles/PMC4896545/
Autor:
Robert S, McNeill, Ralf S, Schmid, Ryan E, Bash, Mark, Vitucci, Kristen K, White, Andrea M, Werneke, Brian H, Constance, Byron, Huff, C Ryan, Miller
Publikováno v:
Journal of visualized experiments : JoVE. (90)
Current astrocytoma models are limited in their ability to define the roles of oncogenic mutations in specific brain cell types during disease pathogenesis and their utility for preclinical drug development. In order to design a better model system f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::53bffcf7d88199dbbbb4a1a7fc08158d
https://pubmed.ncbi.nlm.nih.gov/25146643
https://pubmed.ncbi.nlm.nih.gov/25146643
Autor:
Byron Huff, Kristen K. White, Ralf S. Schmid, Brian H. Constance, Ryan E. Bash, Andrea M. Werneke, C. Ryan Miller, Robert S. McNeill, Mark Vitucci
Publikováno v:
Journal of Visualized Experiments.
Current astrocytoma models are limited in their ability to define the roles of oncogenic mutations in specific brain cell types during disease pathogenesis and their utility for preclinical drug development. In order to design a better model system f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29fa7ca9baba7f87ea6445a94734f9aa
https://doi.org/10.3791/51763-v
https://doi.org/10.3791/51763-v
Autor:
C. Ryan Miller, Kristen K. White, Robert S. McNeill, Ralf S. Schmid, Sophie Wang, Terry Van Dyke, Mark Vitucci, Andrea M. Werneke, Byron Huff, Ryan E. Bash, Natalie O. Karpinich
Publikováno v:
Neuro-oncology. 15(10)
Glioblastoma (GBM) genomes feature recurrent genetic alterations that dysregulate core intracellular signaling pathways, including the G1/S cell cycle checkpoint and the MAPK and PI3K effector arms of receptor tyrosine kinase (RTK) signaling. Elucida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06081d1c302d53ddd64a18e5b5624e08
https://pubmed.ncbi.nlm.nih.gov/23814263
https://pubmed.ncbi.nlm.nih.gov/23814263
Autor:
Lauren Huey, Matthew G. Ewend, Kristen K. White, Jing Wu, Robert S. McNeill, Mark Vitucci, Ralf S. Schmid, Ryan E. Bash, C. Ryan Miller, Andrea M. Werneke
Publikováno v:
Neuro-Oncology. 17:v68.4-v68
BACKGROUND: Glioma stem cells isolated from human glioblastomas are resistant to radiation and cytotoxic chemotherapy and may drive tumor recurrence. Treatment efficacy may depend on the presence of glioma stem cells, expression of DNA repair enzymes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d987473be1188aeaadf30f667881c15a
https://doi.org/10.1093/neuonc/nov210.14
https://doi.org/10.1093/neuonc/nov210.14
Publikováno v:
Cancer Research. 72:3302-3302
Astrocytomas, including glioblastomas (GBM), are characterized by cellular, molecular, and morphological heterogeneity, which raises the question from which cells astrocytomas originate. Research with many different types of cancer has established th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9e80fc6e65562826f7016597c1215d6
https://doi.org/10.1158/1538-7445.am2012-3302
https://doi.org/10.1158/1538-7445.am2012-3302