MicroRNA layer of MHC in infectious diseases

Autor: Erika Ferreira dos Santos, Andrea Luciana Soares da Silva, Sâmila Natiane Ferreira, Eduardo José Melo dos Santos, Mauro de Meira Leite, Monique Suellen Lima da Silveira

Publikováno v: Human Immunology. 80:243-247

The Major Histocompatibility Complex (MHC) harbors key genes of the immune response that are likely useful as biomarkers for infectious diseases. However, little is known about their microRNAs and what role they play in infections. The present study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcb6758d9c6070b628c086fb955c06f8
https://doi.org/10.1016/j.humimm.2019.02.006

Association of the IFNG +874T/A Polymorphism with Symptomatic COVID-19 Susceptibility

Autor: Kevin Matheus Lima de Sarges, Flávia Póvoa da Costa, Erika Ferreira dos Santos, Marcos Henrique Damasceno Cantanhede, Rosilene da Silva, Adriana de Oliveira Lameira Veríssimo, Maria de Nazaré do Socorro de Almeida Viana, Fabíola Brasil Barbosa Rodrigues, Mauro de Meira Leite, Maria Karoliny da Silva Torres, Christiane Bentes da Silva, Mioni Thieli Figueiredo Magalhães de Brito, Andréa Luciana Soares da Silva, Daniele Freitas Henriques, Izaura Maria Vieira Cayres Vallinoto, Giselle Maria Rachid Viana, Maria Alice Freitas Queiroz, Antonio Carlos Rosário Vallinoto, Eduardo José Melo dos Santos

Publikováno v: Viruses, Vol 16, Iss 4, p 650 (2024)

Tumor necrosis factor (TNF) and interferon-gamma (IFNγ) are important inflammatory mediators in the development of cytokine storm syndrome (CSS). Single nucleotide polymorphisms (SNPs) regulate the expression of these cytokines, making host genetics

Externí odkaz: https://doaj.org/article/472bbf52db92457eb2b8c4b988fbda85

Origins and demographic dynamics of Tupí expansion: a genetic tale

Autor: Louise Y. Takeshita, Eduardo José Melo dos Santos, Maria Helena Thomaz Maia, Paloma Daguer Ewerton, Andrea Luciana Soares da Silva

Publikováno v: Boletim do Museu Paraense Emílio Goeldi. Ciências Humanas v.10 n.2 2015
Boletim do Museu Paraense Emílio Goeldi. Ciências Humanas
Museu Paraense Emílio Goeldi (MPEG)
instacron:MPEG
Boletim do Museu Paraense Emílio Goeldi. Ciências Humanas, Vol 10, Iss 2, Pp 217-228
Boletim do Museu Paraense Emílio Goeldi. Ciências Humanas, Volume: 10, Issue: 2, Pages: 217-228, Published: AUG 2015

Tupí linguistic groups display a wide geographical dispersion in South America, probably originated, as pointed by linguistic, from Madeira-Guaporé Region (MGR) in Brazil. The present study reviewed genetic data on Tupians for autosomal and unipare

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b723e22aa3f4bfcae814bfb891b812f1
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1981-81222015000200217

Association of Polymorphisms of IL-6 Pathway Genes (IL6, IL6R and IL6ST) with COVID-19 Severity in an Amazonian Population

Autor: Fabíola Brasil Barbosa Rodrigues, Rosilene da Silva, Erika Ferreira dos Santos, Mioni Thieli Figueiredo Magalhães de Brito, Andréa Luciana Soares da Silva, Mauro de Meira Leite, Flávia Póvoa da Costa, Maria de Nazaré do Socorro de Almeida Viana, Kevin Matheus Lima de Sarges, Marcos Henrique Damasceno Cantanhede, Adriana de Oliveira Lameira Veríssimo, Mayara da Silva Carvalho, Daniele Freitas Henriques, Carla Pinheiro da Silva, Igor Brasil Costa, Juliana Abreu Lima Nunes, Iran Barros Costa, Giselle Maria Rachid Viana, Maria Alice Freitas Queiroz, Sandra Souza Lima, Jeferson da Costa Lopes, Maria Karoliny da Silva Torres, Izaura Maria Vieira Cayres Vallinoto, Carlos David Araújo Bichara, Antonio Carlos Rosário Vallinoto, Eduardo José Melo dos Santos

Publikováno v: Viruses, Vol 15, Iss 5, p 1197 (2023)

Interleukin-6 has been recognized as a major role player in COVID-19 severity, being an important regulator of the cytokine storm. Hence, the evaluation of the influence of polymorphisms in key genes of the IL-6 pathway, namely IL6, IL6R, and IL6ST,

Externí odkaz: https://doaj.org/article/9d3ba056670a4711b3c0fc48df07d3e6

Antibody Response to the SARS-CoV-2 Spike and Nucleocapsid Proteins in Patients with Different COVID-19 Clinical Profiles

Autor: Sinei Ramos Soares, Maria Karoliny da Silva Torres, Sandra Souza Lima, Kevin Matheus Lima de Sarges, Erika Ferreira dos Santos, Mioni Thieli Figueiredo Magalhães de Brito, Andréa Luciana Soares da Silva, Mauro de Meira Leite, Flávia Póvoa da Costa, Marcos Henrique Damasceno Cantanhede, Rosilene da Silva, Adriana de Oliveira Lameira Veríssimo, Izaura Maria Vieira Cayres Vallinoto, Rosimar Neris Martins Feitosa, Juarez Antônio Simões Quaresma, Tânia do Socorro Souza Chaves, Giselle Maria Rachid Viana, Luiz Fábio Magno Falcão, Eduardo José Melo dos Santos, Antonio Carlos Rosário Vallinoto, Andréa Nazaré Monteiro Rangel da Silva

Publikováno v: Viruses, Vol 15, Iss 4, p 898 (2023)

The first case of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), in Brazil was diagnosed on February 26, 2020. Due to the important epidemiological impact of COVID-19, the present study ai

Externí odkaz: https://doaj.org/article/d94907565af34f9ca3ca910ecb21ae09