Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Andrea L. Talis"'
Publikováno v:
Journal of Biological Chemistry. 274:18785-18792
The human papilloma virus E6-associated protein (E6AP) functions as a ubiquitin protein ligase (E3) in the E6-mediated ubiquitination of p53. E6AP is also an E3 in the absence of E6, but its normal cellular substrates have not yet been identified. He
Publikováno v:
Journal of Biological Chemistry. 273:6439-6445
The E6 protein encoded by the oncogenic human papillomaviruses (HPVs) targets p53 for ubiquitin-dependent proteolysis. E6-mediated p53 degradation requires the 100-kDa cellular protein E6-associated protein (E6AP). E6AP and E6 together provide the E3
Publikováno v:
Journal of Adolescent Health. 12:329-334
Traditionally, only symptomatic males or those with a history of exposure are tested for sexually transmitted diseases (STDs). Since urethral infections with Chlamydia trachomatis and Neisseria gonorrhoeae are frequently asymptomatic, a practical, se
Publikováno v:
Journal of virology. 74(14)
The E6 protein of the high-risk human papillomaviruses (HPVs) and the cellular ubiquitin-protein ligase E6AP form a complex which causes the ubiquitination and degradation of p53. We show here that HPV16 E6 promotes the ubiquitination and degradation
Publikováno v:
Journal of Adolescent Health Care. 11:269