Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Andrea L. MacDonald"'
Autor:
Jaclyn R. Espinosa, Danny Mou, Bartley W. Adams, Louis R. DiBernardo, Andrea L. MacDonald, MacKenzie McRae, Allison N. Miller, Mingqing Song, Linda L. Stempora, Jun Wang, Neal N. Iwakoshi, Allan D. Kirk
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
CD28:CD80/86 pathway costimulation blockade (CoB) with the CD80/86-specific fusion protein CTLA4-Ig prevents T cell-mediated allograft rejection in mice. However, in humans, transplantation with CoB has been hampered by CoB-resistant rejection (CoBRR
Externí odkaz:
https://doaj.org/article/9b50cf9d8dea4c1f9954c7be7dcd7634
Autor:
Bradley H. Collins, T.A. Springer, C. Lu, Allan D. Kirk, Keith A. Reimann, K.D. Williams, Francis Leopardi, S.C. Kachlany, K.S. Franke, B.S. Parker, Andrea L. MacDonald, Alton B. Farris, D.A. Anderson, Denise J. Lo, M. Song, Tam How, Michael S. Mulvihill, Kannan P. Samy
Publikováno v:
American Journal of Transplantation. 17:1193-1203
Costimulation blockade (CoB) via belatacept is a lower morbidity alternative to calcineurin inhibitor (CNI)-based immunosuppression. However, it has higher rates of early acute rejection. These early rejections are mediated in part by memory T cells,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5620cf55cd231aebe76a5200d6a93ad5
https://doi.org/10.1111/ajt.14141
https://doi.org/10.1111/ajt.14141
Autor:
Stephen Sacks, Miriam Manook, Anthony Dorling, Verna Curfman, Richard A. G. Smith, He Xu, Evelyn Branum, Andrea L. MacDonald, Kyle Freischlag, Kannan P. Samy, Stuart J. Knechtle, Janghoon Yoon, Michael S. Mulvihill, Alton B. Farris, David N. Howell, Jean Kwun, Christian Burghuber, Nizam Mamode
Publikováno v:
Manook, M, Kwun, J, Burghuber, C, Samy, K, Mulvihill, M, Yoon, J, Xu, H, MacDonald, A L, Freischlag, K, Curfman, V, Branum, E, Howell, D, Farris, A B, Smith, R A, Sacks, S, Dorling, A, Mamode, N & Knechtle, S J 2017, ' Thrombalexin: use of a cytotopic anticoagulant to reduce thrombotic microangiopathy in a highly sensitized model of kidney transplantation ', American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, vol. 17, no. 8, pp. 2055-2064 . https://doi.org/10.1111/ajt.14234
Early activation of coagulation is an important factor in the initiation of innate immunity, as characterized by thrombotic microangiopathy (TMA). In transplantation, systemic anti-coagulation is difficult due to bleeding. A novel 'cytotopic' agent,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7f498418133ff3928c31eff99180fd1
https://pubmed.ncbi.nlm.nih.gov/29083552
https://pubmed.ncbi.nlm.nih.gov/29083552
Autor:
Nicole L. Schramm-Sapyta, Colby Keistler, Reynold Francis, Lauren O’Neill, Cynthia M. Kuhn, Andrea L. MacDonald
Vulnerability to alcoholism is determined by many factors, including the balance of pleasurable vs. aversive alcohol-induced sensations: pleasurable sensations increase intake, while aversive sensations decrease it. Female sex and adolescent age are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b02a805444801dc7213bac10e050271f
https://europepmc.org/articles/PMC4058910/
https://europepmc.org/articles/PMC4058910/
Autor:
Andrew S Barbas, Liwen Lin, MacKenzie McRae, Andrea L MacDonald, Tracy Truong, Yiping Yang, Todd V Brennan
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0200877 (2018)
Despite advances in management of immunosuppression, graft rejection remains a significant clinical problem in solid organ transplantation. Non-invasive biomarkers of graft rejection can facilitate earlier diagnosis and treatment of acute rejection.
Externí odkaz:
https://doaj.org/article/6635221561544cbdb0d5c97d3267450b