Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Andrea L. Halweg-Edwards"'
Publikováno v:
Metabolic Engineering Communications, Vol 3, Iss , Pp 227-233 (2016)
We previously introduced the LASER database (Learning Assisted Strain EngineeRing, https://bitbucket.org/jdwinkler/laser_release) (Winkler et al. 2015) to serve as a platform for understanding past and present metabolic engineering practices. Over th
Externí odkaz:
https://doaj.org/article/f6ea9c6cc6d9470a80744e8ebc3596f4
Publikováno v:
Metabolic Engineering Communications, Vol 2, Iss , Pp 30-38 (2015)
The ability of metabolic engineers to conceptualize, implement, and evaluate strain designs has dramatically increased in the last decade. Unlike other engineering fields, no centralized, open-access, and easily searched repository exists for catalog
Externí odkaz:
https://doaj.org/article/9a31ee6f051c4d94a09b58349bb09076
Autor:
Tyson R. Shepherd, Clint Davis, Charles D. Johnson, Stephen Tanner, Jocelyne Bruand, Thomas Hraha, Tian Tian, Steven Alvarez, Eric Abbate, Shea Lambert, Timothy M. Shaver, Bryan A Leland, Paul Hardenbol, Michael Graige, Stephen Federowicz, Mathew Barber, Scott Bolte, Christopher G. Abraham, Miles Gander, Simon Cawley, Gozde Gencer, J. Christian J. Ray, Andrew D. Garst, Richard Fox, Maciej Swat, Surbhi Jain, Matthew Estes, Kara Juneau, Craig A. Struble, Ken Wishart, Andrea L. Halweg-Edwards, Deanna M. Church, Francesca Pearson, Eileen Colie Spindler, Nandini Krishnamurthy, Chad Sanada, Joshua Shorenstein
Genome engineering methodologies are transforming biological research and discovery. Approaches based on CRISPR technology have been broadly adopted and there is growing interest in the generation of massively parallel edited cell libraries. Comparin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fe0e8bc1ff7b70e400f9a7f173cf58a
https://doi.org/10.1101/2021.09.23.458228
https://doi.org/10.1101/2021.09.23.458228
Autor:
James D. Winkler, Alaksh Choudhury, Ryan T. Gill, Keesha E. Erickson, Andrea L. Halweg-Edwards
Publikováno v:
Current Opinion in Biotechnology. 36:107-114
Metabolic engineers manipulate intricate biological networks to build efficient biological machines. The inherent complexity of this task, derived from the extensive and often unknown interconnectivity between and within these networks, often prevent
Publikováno v:
Biotechnology and Bioengineering. 113:7-10
Publikováno v:
Current Opinion in Chemical Biology. 28:150-155
Since the 1970s technological advancements in the fields of synthetic biology and metabolic engineering have led to a dramatic reduction in both time and cost required for generating genomic mutations in a variety of organisms. The union of genomic e
Publikováno v:
ACS Synthetic Biology. 5:1021-1023
Saturation mutagenesis is widely used in protein engineering and other experiments. A common practice is to utilize the single degenerate codon NNK. However, this approach suffers from amino acid bias and the presence of a stop codon and of the wild
Autor:
Andrea L. Halweg-Edwards, Alaksh Choudhury, Ryan T. Gill, James D. Winkler, Gur Pines, Keesha E. Erickson
Publikováno v:
ACS synthetic biology. 5(12)
The microbial ability to resist stressful environmental conditions and chemical inhibitors is of great industrial and medical interest. Much of the data related to mutation-based stress resistance, however, is scattered through the academic literatur
Autor:
James T. Morton, Philip H. Siebler, Andrea L. Halweg-Edwards, James E. Hassell, Charles L. Raison, James H. Fox, Frederick R. Walker, Rob Knight, Charline Jansch, Dominik Langgartner, Kenneth R. Lowe, Matthew W. Hale, Gerardo Lopez Perez, Jared M. Kopelman, Will Van Treuren, Anja Lechner, Nicole Uschold-Schmidt, Nina C. Donner, Shyamal D. Peddada, Antonio Gonzalez, Benjamin N. Greenwood, Dominic Schmidt, Graham A. W. Rook, Christopher A. Lowry, Monika Fleshner, Kristen J. Wheeler, Andrea M. Füchsl, Stefan O. Reber, David G. Smith
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 113, iss 22
The prevalence of inflammatory diseases is increasing in modern urban societies. Inflammation increases risk of stress-related pathology; consequently, immunoregulatory or antiinflammatory approaches may protect against negative stress-related outcom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48630380434c84a5dccd079b4a244526
https://escholarship.org/uc/item/8jx3r6ns
https://escholarship.org/uc/item/8jx3r6ns
Publikováno v:
Metabolic Engineering Communications
Metabolic Engineering Communications, Vol 3, Iss, Pp 227-233 (2016)
Metabolic Engineering Communications, Vol 3, Iss, Pp 227-233 (2016)
We previously introduced the LASER database (Learning Assisted Strain EngineeRing, https://bitbucket.org/jdwinkler/laser_release) (Winkler et al. 2015) to serve as a platform for understanding past and present metabolic engineering practices. Over th