Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Andrea Kuchtová"'
1
Akademický článek
An empirical pipeline for personalized diagnosis of Lafora disease mutations
Autor: M. Kathryn Brewer, Maria Machio-Castello, Rosa Viana, Jeremiah L. Wayne, Andrea Kuchtová, Zoe R. Simmons, Sarah Sternbach, Sheng Li, Maria Adelaida García-Gimeno, Jose M. Serratosa, Pascual Sanz, Craig W. Vander Kooi, Matthew S. Gentry
Publikováno v: iScience, Vol 24, Iss 11, Pp 103276- (2021)
Summary: Lafora disease (LD) is a fatal childhood dementia characterized by progressive myoclonic epilepsy manifesting in the teenage years, rapid neurological decline, and death typically within ten years of onset. Mutations in either EPM2A, encodin
Externí odkaz: https://doaj.org/article/08a505503d644df58c43dc58bd8a2937
Zobrazit plný text záznamu
2
An empirical pipeline for personalized diagnosis of Lafora disease mutations
Autor: Pascual Sanz, Sheng Li, Craig W. Vander Kooi, Jeremiah Wayne, Andrea Kuchtová, Maria Machio-Castello, Zoe R. Simmons, Sarah Sternbach, M. Kathryn Brewer, Matthew S. Gentry, Maria Adelaida Garcia-Gimeno, Rosa Viana, Jose M. Serratosa
Publikováno v: iScience, Vol 24, Iss 11, Pp 103276-(2021)
Digital.CSIC. Repositorio Institucional del CSIC
instname
iScience
Summary Lafora disease (LD) is a fatal childhood dementia characterized by progressive myoclonic epilepsy manifesting in the teenage years, rapid neurological decline, and death typically within ten years of onset. Mutations in either EPM2A, encoding
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9308a5ffc8ace0f0db228c5c5c0ceb42
http://www.sciencedirect.com/science/article/pii/S2589004221012451
Zobrazit plný text záznamu
3
Cooperative Kinetics of the Glucan Phosphatase Starch Excess4
Autor: Kenyon Weis, Madushi Raththagala, Matthias Thalmann, Savita Sharma, Claudia Mak, David A. Meekins, Craig W. Vander Kooi, Tiffany Henao, Andrea Kuchtová, Tiantian Chen
Publikováno v: Biochemistry. 60(31)
Glucan phosphatases are members of a functionally diverse family of dual-specificity phosphatase (DSP) enzymes. The plant glucan phosphatase Starch Excess4 (SEX4) binds and dephosphorylates glucans, contributing to processive starch degradation in th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::947853404bad670b9e13c1378064063a
https://pubmed.ncbi.nlm.nih.gov/34319705
Zobrazit plný text záznamu
5
The unique evolution of the carbohydrate-binding module CBM20 in laforin
Autor: Štefan Janeček, Matthew S. Gentry, Andrea Kuchtová
Laforin catalyses glycogen dephosphorylation. Mutations in its gene result in Lafora disease, a fatal progressive myoclonus epilepsy, the hallmark being water-insoluble, hyperphosphorylated carbohydrate inclusions called Lafora bodies. Human laforin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c90318db26fc3496d6b21dabb494165
https://europepmc.org/articles/PMC5829021/
Zobrazit plný text záznamu
6
In silico analysis of family GH77 with focus on amylomaltases from borreliae and disproportionating enzymes DPE2 from plants and bacteria
Autor: Andrea Kuchtová, Štefan Janeček
Publikováno v: Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1854:1260-1268
The CAZy glycoside hydrolase (GH) family GH77 is a monospecific family containing 4-α-glucanotransferases that if from prokaryotes are known as amylomaltases and if from plants including algae are known as disproportionating enzymes (DPE). The famil
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc8806183a6d6ba7fafc4e343ded038
https://doi.org/10.1016/j.bbapap.2015.05.009
Zobrazit plný text záznamu
7
A novel GH13 subfamily of α-amylases with a pair of tryptophans in the helix α3 of the catalytic TIM-barrel, the LPDlx signature in the conserved sequence region V and a conserved aromatic motif at the C-terminus
Autor: Soňa Petrovičová, Štefan Janeček, Andrea Kuchtová
Publikováno v: Biologia. 70:1284-1294
The α-amylase enzyme specificity has been classified in the Carbohydrate-Active enZyme (CAZy) database into the families GH13, GH57, GH119 and eventually also GH126. α-Amylase is a glycoside hydrolase (GH) that catalyses in an endo-fashion the hydr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eb5935281a80230ae120df1aa1cf418e
https://doi.org/10.1515/biolog-2015-0165
Zobrazit plný text záznamu
8
Domain evolution in enzymes of the neopullulanase subfamily
Autor: Andrea Kuchtová, Štefan Janeček
Publikováno v: Microbiology (Reading, England). 162(12)
Among the glycoside hydrolases (GHs) classified within the Carbohydrate-Active enZyme (CAZy) database, the α-amylase family GH13 containing ~30 different enzyme specificities and more than 37 000 sequences represents one of the largest GH families.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7870fc71b5e39a450ac8044637df0ab3
https://pubmed.ncbi.nlm.nih.gov/27902421
Zobrazit plný text záznamu
9
In silico identification of catalytic residues and domain fold of the family GH119 sharing the catalytic machinery with the α-amylase family GH57
Autor: Andrea Kuchtová, Štefan Janeček
Publikováno v: FEBS Letters. 586:3360-3366
The glycoside hydrolase family 119 (GH119) contains the α-amylase from Bacillus circulans and five other hypothetical proteins. Until now, nothing has been reported on the catalytic residues and catalytic-domain fold of GH119. Based on a detailed in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a20db97cd055ef31baf751f62a691452
https://doi.org/10.1016/j.febslet.2012.07.020
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje