Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Andrea Kröger"'
Autor:
Sergio Passarella, Shananthan Kethiswaran, Karina Brandes, I-Chin Tsai, Kristin Cebulski, Andrea Kröger, Daniela C. Dieterich, Peter Landgraf
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
The cGAS-STING pathway is a pivotal element of the innate immune system, recognizing cytosolic DNA to initiate the production of type I interferons and pro-inflammatory cytokines. This study investigates the alterations of the cGAS-STING signaling co
Externí odkaz:
https://doaj.org/article/778753a5538849f085d11c7efcf86fd3
Autor:
Loreen Weichert, Henning Peter Düsedau, David Fritzsch, Sarah Schreier, Annika Scharf, Martina Grashoff, Kristin Cebulski, Kristin Michaelsen-Preusse, Christian Erck, Stefan Lienenklaus, Ildiko Rita Dunay, Andrea Kröger
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-15 (2023)
Abstract Background Type I interferons (IFN-I) are fundamental in controlling viral infections but fatal interferonopathy is restricted in the immune-privileged central nervous system (CNS). In contrast to the well-established role of Interferon Regu
Externí odkaz:
https://doaj.org/article/71c342895e60461891bb891d8d2c9c73
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
MAIT cells are multifunctional innate-like effector cells recognizing bacterial-derived vitamin B metabolites presented by the non-polymorphic MHC class I related protein 1 (MR1). However, our understanding of MR1-mediated responses of MAIT cells upo
Externí odkaz:
https://doaj.org/article/2ad405d16cf840c0a1e5ef2e5f3cebd2
Autor:
Caio Andreeta Figueiredo, Johannes Steffen, Lorena Morton, Sushmitha Arumugam, Oliver Liesenfeld, Mária A. Deli, Andrea Kröger, Thomas Schüler, Ildiko Rita Dunay
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-18 (2022)
Abstract Background Toxoplasma gondii (T. gondii) is a highly successful parasite being able to cross all biological barriers of the body, finally reaching the central nervous system (CNS). Previous studies have highlighted the critical involvement o
Externí odkaz:
https://doaj.org/article/1acbe1ca429f47faaaff52a7ddae5f81
Autor:
Beatrice T. Laudenbach, Karsten Krey, Quirin Emslander, Line Lykke Andersen, Alexander Reim, Pietro Scaturro, Sarah Mundigl, Christopher Dächert, Katrin Manske, Markus Moser, Janos Ludwig, Dirk Wohlleber, Andrea Kröger, Marco Binder, Andreas Pichlmair
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
RNA of some viruses is protected from degradation by a 5′ triphosphate group. Here the authors identify nudix hydrolase 2 (NUDT2) as novel antiviral defense protein that dephosphorylates viral RNA and thereby enables its degradation.
Externí odkaz:
https://doaj.org/article/83808abd13804cb1901e95ef41afb37f
Autor:
Federico Bertoglio, Doris Meier, Nora Langreder, Stephan Steinke, Ulfert Rand, Luca Simonelli, Philip Alexander Heine, Rico Ballmann, Kai-Thomas Schneider, Kristian Daniel Ralph Roth, Maximilian Ruschig, Peggy Riese, Kathrin Eschke, Yeonsu Kim, Dorina Schäckermann, Mattia Pedotti, Philipp Kuhn, Susanne Zock-Emmenthal, Johannes Wöhrle, Normann Kilb, Tobias Herz, Marlies Becker, Martina Grasshoff, Esther Veronika Wenzel, Giulio Russo, Andrea Kröger, Linda Brunotte, Stephan Ludwig, Viola Fühner, Stefan Daniel Krämer, Stefan Dübel, Luca Varani, Günter Roth, Luka Čičin-Šain, Maren Schubert, Michael Hust
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Antibodies targeting the spike protein of coronaviruses are potential candidates for therapeutic development. Here, Bertoglio et al. use phage display to select anti-SARS-CoV-2 spike antibodies from the human naïve universal antibody gene libraries
Externí odkaz:
https://doaj.org/article/0dc5d5dbf361487e9f729846cf72c808
Autor:
Angela D. A. Cornelius, Shirin Hosseini, Sarah Schreier, David Fritzsch, Loreen Weichert, Kristin Michaelsen-Preusse, Markus Fendt, Andrea Kröger
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-17 (2020)
Abstract Background Tick-borne encephalitis virus (TBEV) is an important human pathogen that can cause the serious illness tick-borne encephalitis (TBE). Patients with clinical symptoms can suffer from severe meningoencephalitis with sequelae that in
Externí odkaz:
https://doaj.org/article/d782faec1519422cb251b18d97ba00e1
Autor:
Richard Lindqvist, Ebba Rosendal, Elvira Weber, Naveed Asghar, Sarah Schreier, Annasara Lenman, Magnus Johansson, Gerhard Dobler, Malena Bestehorn, Andrea Kröger, Anna K. Överby
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-15 (2020)
Abstract Background Tick-borne encephalitis virus (TBEV) is considered to be the medically most important arthropod-borne virus in Europe. The symptoms of an infection range from subclinical to mild flu-like disease to lethal encephalitis. The exact
Externí odkaz:
https://doaj.org/article/22103c3f7551406591b9ccdefc13884e
Autor:
Johannes Schwerk, Lucas Kemper, Kendra A. Bussey, Stefan Lienenklaus, Siegfried Weiss, Luka Čičin-Šain, Andrea Kröger, Ulrich Kalinke, Christopher M. Collins, Samuel H. Speck, Martin Messerle, Dagmar Wirth, Melanie M. Brinkmann, Hansjörg Hauser, Mario Köster
Publikováno v:
Pathogens, Vol 11, Iss 12, p 1554 (2022)
Gammaherpesviruses, such as Epstein-Barr virus and Kaposi’s sarcoma-associated herpesvirus, are important human pathogens involved in lymphoproliferative disorders and tumorigenesis. Herpesvirus infections are characterized by a biphasic cycle comp
Externí odkaz:
https://doaj.org/article/2db1caf9db6a4ebcb475422ae96a09da
Autor:
Henning Peter Düsedau, Johannes Steffen, Caio Andreeta Figueiredo, Julia Désirée Boehme, Kristin Schultz, Christian Erck, Martin Korte, Heidi Faber-Zuschratter, Karl-Heinz Smalla, Daniela Dieterich, Andrea Kröger, Dunja Bruder, Ildiko Rita Dunay
Publikováno v:
mBio, Vol 12, Iss 5 (2021)
Influenza A virus (IAV) causes respiratory tract disease and is responsible for seasonal and reoccurring epidemics affecting all age groups. Next to typical disease symptoms, such as fever and fatigue, IAV infection has been associated with behaviora
Externí odkaz:
https://doaj.org/article/eb7d670ada984248b1e1a32cc7c30ca6