Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Andrea Kew"'
Autor:
Bruno C. Medeiros, Kelly McCaul, Suman Kambhampati, Daniel A. Pollyea, Rajat Kumar, Lewis R. Silverman, Andrea Kew, Lalit Saini, CL Beach, Ravi Vij, Xiwei Wang, Jim Zhong, Robert Peter Gale
Publikováno v:
Haematologica, Vol 103, Iss 1 (2018)
Therapy of acute myeloid leukemia in older persons is associated with poor outcomes because of intolerance to intensive therapy, resistant disease and co-morbidities. This multi-center, randomized, open-label, phase II trial compared safety and effic
Externí odkaz:
https://doaj.org/article/996424bd79e3482db71368b705848b5c
Autor:
Eberhard L. Renner, David M. Grant, Harold Atkins, Natasha Kekre, Mark S. Cattral, Andrzej Chruscinski, Andrea Kew, Anne Marie Clement, Mitchell Sabloff, Kathryn Tinckham, David S. Allan, Robert B. Smith, Christopher Bredeson, Oyedele Adeyi, Anthony J. Demetris, Tae Kyoung Kim, Jianhua Zhang, Leslie B. Lilly, Atul Humar, Meaghan Macarthur, Sultan Altouri, S. Moshkelgosha, Isabelle Bence-Bruckler, Paul D. Greig, Stephen C. Juvet, Nazia Selzner, Tae Joon Yi, Anand Ghanekar, Korosh Khalili, Ian D. McGilvray, Gonzalo Sapisochin, Lisa Martin, Zita Galvin, Maor Epstein, Lothar Huebsch, Sandra Fischer, Jill Fulcher, Sheryl McDiarmid, Markus Selzner, Gary A. Levy
Publikováno v:
Transplantation. 106(3)
Background Primary sclerosing cholangitis (PSC) is an indication for liver transplantation, but recurrence after liver transplantation is associated with poor outcomes often requiring repeat transplantation. We investigated whether autologous hematop
Autor:
Sean Dolan, Max Sherry, Irwindeep Sandhu, Christine Chen, Arleigh McCurdy, Christopher P. Venner, Andrea Kew, Annette E. Hay, Martha L Louzada, Richard Leblanc, Tony Reiman, Gail T. McDonald, Marc Lalancette, Bingshu E. Chen, Andrew R. Belch, Engin Gul, Donna E. Reece, Bethany Monteith, Darrell White
Publikováno v:
American journal of hematologyREFERENCES. 96(5)
The MCRN-003/CCTGMYX.1 is a single arm phase II trial of weekly carfilzomib, cyclophosphamide and dexamethasone (wKCd), exploring a convenient immunomodulator (IMiD)-free regimen in relapsed myeloma. Weekly carfilzomib (20/70 mg/m2 ), dexamethasone 4
Autor:
Jocelyn S. Garland, Joseph L. Pater, Annette E. Hay, Andrea Kew, Marc Lalancette, Christopher P. Venner, Donna E. Reece, Lois E. Shepherd, Bethany Monteith
Publikováno v:
Clinical lymphoma, myelomaleukemia. 20(11)
Thrombotic microangiopathy (TMA) is a life-threatening clinical syndrome characterized by hemolytic anemia, thrombocytopenia, and microvascular thrombosis, resulting in ischemia and organ damage. Multiple myeloma (MM) is a neoplasm arising from clona
Autor:
Danny C C Lin, Arleigh McCurdy, Christopher R. McCudden, Natasha Rupani, Andrea Kew, Ronald A. Booth
Publikováno v:
Clinical Biochemistry. 51:21-28
Autor:
Nancy Zhu, April Shamy, Ambica Parmar, Heather A. Leitch, Richard A. Wells, Michelle Geddes, Andrea Kew, Robert Delage, Alexandre Mamedov, Eve St. Hilaire, Martha Lenis, Janika Francis, Rajat Kumar, Lisa Chodirker, Mohamed Elemary, Rena Buckstein, Mary-Margaret Keating, Thomas J. Nevill, Brian Leber, Mitchell Sabloff, Karen W.L. Yee, Jessica Ivo, John M. Storring, Liying Zhang
Publikováno v:
British Journal of Haematology. 179:83-97
Summary Analyses suggest iron overload in red blood cell (RBC) transfusion-dependent (TD) patients with myleodysplastic syndrome (MDS) portends inferior overall survival (OS) that is attenuated by iron chelation therapy (ICT) but may be biassed by un
Autor:
Gail T. McDonald, Bingshu E. Chen, Max Sherry, Marc Lalancette, Arleigh McCurdy, Sean Dolan, Richard Leblanc, Bethany Monteith, Irwindeep Sandhu, Engin Gul, Tony Reiman, Andrea Kew, Darrell White, Martha L Louzada, Andrew Belch, Christopher P. Venner, Christine Chen, Annette E. Hay, Donna E. Reece
Publikováno v:
Blood. 134:1871-1871
Background: Carfilzomib is effective in the treatment of relapsed and refractory multiple myeloma (RRMM). Questions remain regarding optimal dosing strategies and combinations. The MCRN-003/MYX.1 single arm phase II clinical trial of high-dose once w
Autor:
Gail T. McDonald, Joe Pater, Andrea Kew, Lois E. Shepherd, Marc Lalancette, Bethany Monteith, Chritopher Venner, Annette E. Hay, Donna E. Reece, Engin Gul, Jocelyn S. Garland
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 19:e272-e273
Autor:
Salah Mahmud, Donna Turner, Anna Serebrin, David M. Jones, Pascal Lambert, Janeve Everett, John M. Storring, Mitchell Sabloff, Kristjan Paulson, Catherine Meloche, Andrea Kew, Julie Bergeron, Ismail Sharif, Matthew D. Seftel
Publikováno v:
British Journal of Haematology. 166:660-666
Timely diagnosis and care are major determinants of the outcome in acute promyelocytic leukaemia (APL), a malignancy whose incidence may be increasing. The Canadian Cancer Registry (CCR) and health system represent valuable settings to study APL epid
Autor:
Bingshu E. Chen, Christine Chen, Annette E. Hay, Laura Rodriguez, Gail T. McDonald, Lois E. Shepherd, Arleigh McCurdy, Donna E. Reece, Darrell White, Richard Leblanc, Engin Gul, Andrea Kew, Martha L Louzada, Andrew Belch, Irwindeep Sandhu, Sean Dolan, Marc Lalancette, Christopher P. Venner, Tony Reiman
Publikováno v:
Blood. 132:1984-1984
Background: Carfilzomib, a second generation proteosome inhibitor, is effective in the treatment of relapsed and refractory multiple myeloma (RRMM). Recent phase II and phase III trials have demonstrated the efficacy of weekly dosing strategies. The