Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Andrea Keppler-Hafkemeyer"'
Autor:
Edwin Quinten, Julieta H. Sepúlveda-Yáñez, Marvyn T. Koning, Janneke A. Eken, Dietmar Pfeifer, Valeri Nteleah, Ruben A.L. de Groen, Diego Alvarez Saravia, Jeroen Knijnenburg, Hedwig E. Stuivenberg-Bleijswijk, Milena Pantic, Andreas Agathangelidis, Andrea Keppler-Hafkemeyer, Cornelis A. M. van Bergen, Roberto Uribe-Paredes, Kostas Stamatopoulos, Joost S.P. Vermaat, Katja Zirlik, Marcelo A. Navarrete, Hassan Jumaa, Hendrik Veelken
Publikováno v:
Haematologica, Vol 109, Iss 3 (2023)
Clonal expansion of CD5-expressing B cells, commonly designated as monoclonal B lymphocytosis (MBL), is a precursor condition for chronic lymphocytic leukemia (CLL). The mechanisms driving subclinical MBL B-cell expansion and progression to CLL, occu
Externí odkaz:
https://doaj.org/article/dba465a131f946e396c780476e81d2fc
Autor:
Dimitrios Papaioannou, Anna-Maria Strothmeyer, Marcus Dühren-von Minden, Andrea Keppler-Hafkemeyer, Katja Zirlik, Kristina Mikesch, Cornelis A.M. van Bergen, Marcelo A. Navarrete, Hendrik Veelken
Publikováno v:
Haematologica, Vol 100, Iss 4 (2015)
Externí odkaz:
https://doaj.org/article/b7f60b95b02a4856a536940287c5612d
Autor:
Andrea Keppler-Hafkemeyer, Christine Greil, Paul R. Wratil, Khalid Shoumariyeh, Marcel Stern, Annika Hafkemeyer, Driti Ashok, Alexandra Hollaus, Gaia Lupoli, Alina Priller, Marie L. Bischof, Gabriele Ihorst, Monika Engelhardt, Reinhard Marks, Jürgen Finke, Hannah Bertrand, Christopher Dächert, Maximilian Muenchhoff, Irina Badell, Florian Emmerich, Hridi Halder, Patricia M. Spaeth, Percy A. Knolle, Ulrike Protzer, Michael von Bergwelt-Baildon, Justus Duyster, Tanja N. Hartmann, Andreas Moosmann, Oliver T. Keppler
Publikováno v:
Nat. Cancer 4, 81–95 (2023)
Individuals with hematologic malignancies are at increased risk for severe coronavirus disease 2019 (COVID-19), yet profound analyses of COVID-19 vaccine-induced immunity are scarce. Here we present an observational study with expanded methodological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7a578dee972e7a71f01fd5c9936e2b2
https://pubmed.ncbi.nlm.nih.gov/36543907
https://pubmed.ncbi.nlm.nih.gov/36543907
Autor:
Kristina Mikesch, Anna-Maria Strothmeyer, Andrea Keppler-Hafkemeyer, Katja Zirlik, Cornelis A.M. van Bergen, Marcelo A. Navarrete, Dimitrios Papaioannou, Hendrik Veelken, Marcus Dühren-von Minden
Publikováno v:
Haematologica, 100(4), E143-E146
Antigen receptors of B cells (BCR) exhibit a virtually unlimited repertoire, created by V(D)J recombination through combinatorial and junctional diversity of genetic elements in B-precursor cells. B cells further increase the antigen affinity of thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05cad864e2967bface318bd447b448ce
https://europepmc.org/articles/PMC4380737/
https://europepmc.org/articles/PMC4380737/
Autor:
Pär Olsson, George Vasmatzis, Andrea Keppler-Hafkemeyer, Xiu Fen Liu, Tapan K. Bera, Byungkook Lee, Noga Yerushalmi, Ira Pastan, Paul H. Duray
Publikováno v:
Gene. 265:55-60
We have identified a new gene, that is highly expressed in normal and neoplastic prostate, and is also expressed in cardiac atrium, salivary gland, spleen and selective cells in the CNS. Database analyses of ESTs indicated prostate specificity but ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a3c1721512af67450b36977806433cd
https://doi.org/10.1016/s0378-1119(01)00347-x
https://doi.org/10.1016/s0378-1119(01)00347-x
Autor:
Darell D. Bigner, Richard A. Beers, Ian A. J. Lorimer, Charles N. Pegram, Ira Pastan, Andrea Keppler-Hafkemeyer
Publikováno v:
Proceedings of the National Academy of Sciences. 93:14815-14820
EGFRvIII is a mutant epidermal growth factor receptor found in glioblastoma, and in carcinoma of the breast, ovary, and lung. The mutant receptor has a deletion in its extracellular domain that results in the formation of a new, tumor-specific extrac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98d9024a9bdb2e1efbb52dcb134f45fc
https://doi.org/10.1073/pnas.93.25.14815
https://doi.org/10.1073/pnas.93.25.14815
Autor:
Kristina Heining-Mikesch, Marcelo A. Navarrete, Hendrik Veelken, Cristina Bertinetti-Lapatki, Andrea Keppler-Hafkemeyer, Gabriele Ihorst, Frank Schüler, Gottfried Dölken
Publikováno v:
Blood, 117(5), 1483-1491
Idiotype vaccination for follicular lymphoma is primarily being developed as remission consolidation after chemotherapy. We investigated idiotype vaccination as primary intervention for treatment-naive indolent B-cell lymphoma and in a separate cohor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e612850dbdaa5d171451394edc651e9
https://doi.org/10.1182/blood-2010-06-292342
https://doi.org/10.1182/blood-2010-06-292342
Publikováno v:
Expert opinion on biological therapy. 1(4)
Recombinant immunotoxins consist of Fv regions of tumour-selective antibodies fused to toxins found in bacteria, plants or fungi. These toxins must be modified to remove normal-tissue binding sites but to retain all other functions of cytotoxicity. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a926709688d8609c24b2f89484311bc9
https://pubmed.ncbi.nlm.nih.gov/11727505
https://pubmed.ncbi.nlm.nih.gov/11727505
Publikováno v:
International journal of cancer. 87(1)
The recombinant immunotoxins anti-Tac(Fv)-PE38 (LMB-2), targeting the interleukin-2 receptor alpha subunit (IL-2Ralpha, Tac or CD25), and RFB4(dsFv)-PE38 (BL22), targeting CD22, are being evaluated in clinical trials as treatment for hematologic mali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aac2f683b13ab7e19849ef87eaabcfc0
https://pubmed.ncbi.nlm.nih.gov/10861457
https://pubmed.ncbi.nlm.nih.gov/10861457
Autor:
Andrea Keppler-Hafkemeyer, Wolf-dieter Lehmann, Hiroshi Fukui, Dietrich Keppler, Winfried Schneider, Masao Fujimoto, Masahito Uemura, Tadasu Tsujii, Peter Hafkemeyer, Hideyuki Kojima, Axel Benner, Helmut K. Seitz
Publikováno v:
Gastroenterology. 118(6)
Leukotrienes are proinflammatory mediators. Ethanol inhibits the catabolism of both cysteinyl leukotrienes (leukotriene E(4) [LTE(4)] and N-acetyl-LTE(4)) and leukotriene B(4) (LTB(4)) in hepatocytes. We examined the metabolic derangement of leukotri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cde9483a33abfe1cc06251bb4172f64
https://pubmed.ncbi.nlm.nih.gov/10833489
https://pubmed.ncbi.nlm.nih.gov/10833489