Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Andrea K. Kress"'
Publikováno v:
Viruses, Vol 3, Iss 8, Pp 1439-1459 (2011)
The phenotype of HTLV-1-transformed CD4+ T lymphocytes largely depends on defined viral effector molecules such as the viral oncoprotein Tax. In this review, we exemplify the expression pattern of characteristic lineage markers, costimulatory recepto
Externí odkaz:
https://doaj.org/article/c069eb9370f1400d9afa23f877a5f955
Publikováno v:
Virology. :98-110
The oncoprotein Tax of human T-cell leukemia virus type 1 (HTLV-1) is a potent transactivator of viral and cellular transcription. Here, we identified ELL2 as the sole transcription elongation factor to be specifically upregulated in HTLV-1-/Tax-tran
Publikováno v:
Journal of Virology. 86:6097-6108
The human APOBEC3 family consists of seven cytidine deaminases (A3A to A3H), some of which display potent antiretroviral activity against HIV-1 and other retroviruses. Studies that analyzed the effect of A3G on human T-lymphotropic virus type 1 (HTLV
Publikováno v:
Viruses, Vol 3, Iss 8, Pp 1439-1459 (2011)
Viruses
Viruses
The phenotype of HTLV-1-transformed CD4(+) T lymphocytes largely depends on defined viral effector molecules such as the viral oncoprotein Tax. In this review, we exemplify the expression pattern of characteristic lineage markers, costimulatory recep
Publikováno v:
Blood. 117:3609-3612
Oncogenic transformation of CD4+ T cells by human T-cell lymphotropic virus type 1 (HTLV-1) is understood as the initial step to adult T-cell leukemia/lymphoma, a process that is mainly initiated by perturbation of cellular signaling by the viral Tax
Autor:
Andrea K. Kress, Ralph Grassmann, Graham P. Taylor, Charles R. M. Bangham, Klemens Pichler, Juliane Gentzsch, Tarek Kattan
Publikováno v:
Blood. 111:4741-4751
Human T-cell leukemia virus type 1 (HTLV-1), the cause of adult T-cell leukemia, stimulates the growth of infected T cells in cultures and in nonleukemic patients. In the latter, HTLV-1 is found in long-term persisting T-cell clones. The persistence
Autor:
Bernhard Fleckenstein, Andrea K. Kress, Grit Schneider, Klemens Pichler, Ralph Grassmann, Martina Kalmer
Publikováno v:
Journal of virology. 84(17)
Human T-cell lymphotropic virus type 1 (HTLV-1), the cause of adult T-cell leukemia/lymphoma (ATLL), transforms CD4+T cells to permanent growth through its transactivator Tax. HTLV-1-transformed cells share phenotypic properties with memory and regul
The tumour marker Fascin is strongly induced by Tax of HTLV-1 through NF-κB signals in T lymphocytes
Publikováno v:
Retrovirology
Europe PubMed Central
Retrovirology, Vol 8, Iss Suppl 1, p A186 (2011)
Europe PubMed Central
Retrovirology, Vol 8, Iss Suppl 1, p A186 (2011)
In search of novel biomarkers of HTLV-1- transformed cells with relevance to oncogenesis, we identified the tumour marker and actin-bundling protein Fascin (FSCN1) to be specifically and strongly upregulated in both HTLV-1-transformed and ATLL-patien
Publikováno v:
Retrovirology
During HTLV-1 gene expression, positive transcription elongation factor b (pTEFb) is recruited to the long terminal repeat by Tax. Usually, additional proteins and elongation factors, known as the super elongation complex (SEC) and acting together wi