Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Andrea J. Manrique-Rincón"'
Autor:
Soledad Palameta, Andrea J. Manrique-Rincón, Jessica M. Toscaro, Isadora F. Semionatto, Matheus C. Fonseca, Rhubia S.M. Rosa, Luciana P. Ruas, Paulo S.L. Oliveira, Marcio C. Bajgelman
Publikováno v:
Molecular Therapy: Oncolytics, Vol 24, Iss , Pp 650-662 (2022)
Therapeutic strategies based on immunomodulation have improved cancer therapy. Most approaches target co-stimulatory pathways or the inhibition of immunosuppressive mechanisms, to enhance immune response and overcome the immune tolerance of tumors. H
Externí odkaz:
https://doaj.org/article/38c6f83535f44f009e9b1c10d5b4c4e8
Autor:
Andrea J. Manrique-Rincón, Luciana P. Ruas, Carolinne T. Fogagnolo, Randall J. Brenneman, Alexey Berezhnoy, Bianca Castelucci, Sílvio R. Consonni, Eli Gilboa, Marcio C. Bajgelman
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 25, Iss , Pp 143-151 (2021)
The inhibition of immunosuppressive mechanisms may switch the balance between tolerance and surveillance, leading to an increase in antitumor activity. Regulatory T cells play an important role in the control of immunosuppression, exhibiting the uniq
Externí odkaz:
https://doaj.org/article/ee7972e930464c6d8062cd9b9ce7fb43
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Recent studies have demonstrated that combination of modulatory immune strategies may potentiate tumor cell elimination. Most strategies rely on the use of monoclonal antibodies that can block cell surface receptors to overcome tumor-induced immunosu
Externí odkaz:
https://doaj.org/article/301c09f8f01c45df86dcdbb359a3cb7c
Autor:
Bianca Gazieri Castelucci, Randall Brenneman, Alexey Berezhnoy, Marcio C. Bajgelman, Carolinne T. Fogagnolo, Andrea J. Manrique-Rincón, Luciana P. Ruas, Eli Gilboa, Sílvio Roberto Consonni
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 25, Iss, Pp 143-151 (2021)
Molecular Therapy: Nucleic Acids, Vol 25, Iss, Pp 143-151 (2021)
The inhibition of immunosuppressive mechanisms may switch the balance between tolerance and surveillance, leading to an increase in antitumor activity. Regulatory T cells play an important role in the control of immunosuppression, exhibiting the uniq
Autor:
Soledad Palameta, Andrea J. Manrique-Rincón, Jessica M. Toscaro, Isadora F. Semionatto, Matheus C. Fonseca, Rhubia S.M. Rosa, Luciana P. Ruas, Paulo S.L. Oliveira, Marcio C. Bajgelman
Publikováno v:
Molecular therapy oncolytics. 24
Therapeutic strategies based on immunomodulation have improved cancer therapy. Most approaches target co-stimulatory pathways or the inhibition of immunosuppressive mechanisms, to enhance immune response and overcome the immune tolerance of tumors. H
Autor:
Soledad Palameta, Isadora Ferraz Semionatto, Jessica M. Toscaro, Adriana Franco Paes Leme, Andrea J. Manrique-Rincón, Luciana P. Ruas, Marcio C. Bajgelman
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Genetically modified tumor cells harboring immunomodulators may be used as therapeutic vaccines to stimulate antitumor immunity. The therapeutic benefit of these tumor vaccines is extensively investigated and mechanisms by which they boost antitumor
Autor:
M. Eugenia Ribeiro de Camargo, Marcio C. Bajgelman, Anna Carolina Vieira de Carvalho, Andrea J. Manrique-Rincón, Kleber G. Franchini
Publikováno v:
Journal of biotechnology. 284
Immunotherapy has revolutionized the treatment of cancer. Since tumor cells exhibit low immunogenicity and can induce several mechanisms of tolerance, the use of monoclonal antibodies or other immunomodulators, targeting costimulation of T cells may