Výsledky vyhledávání - "Andrea J. Elberger"

Akademický článek

A Novel Closed-head Model of Mild Traumatic Brain Injury Caused by Primary Overpressure Blast to the Cranium Produces Sustained Emotional Deficits in Mice

Autor: Scott A Heldt, Andrea J Elberger, Yunping eDeng, Natalie H Guley, Nobel eDel Mar, Joshua eRogers, Gy Won eChoi, Jessica eFerrell, Tonia S Rex, Marcia G Honig, Anton eReiner

Publikováno v: Frontiers in Neurology, Vol 5 (2014)

Emotional disorders are a common outcome from mild traumatic brain injury (TBI) in humans, but their pathophysiological basis is poorly understood. We have developed a mouse model of closed-head blast injury using an air pressure wave delivered to a

Externí odkaz: https://doaj.org/article/0d512526296f4c7fab8576eedc7ed4e1

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Motor, Visual and Emotional Deficits in Mice after Closed-Head Mild Traumatic Brain Injury Are Alleviated by the Novel CB2 Inverse Agonist SMM-189

Autor: Chaela S. Presley, Jessica Ferrell, Nobel Del Mar, Yunping Deng, Lauren D'Surney, Steven N. Gurley, Natalie H. Guley, Wei Bu, Scott A. Heldt, Andrea J. Elberger, Anton Reiner, Marcia G. Honig, Bob M. Moore, Joshua T. Rogers

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 16, Iss 1, Pp 758-787 (2014)
Volume 16
Issue 1
Pages 758-787

We have developed a focal blast model of closed-head mild traumatic brain injury (TBI) in mice. As true for individuals that have experienced mild TBI, mice subjected to 50–60 psi blast show motor, visual and emotional deficits, diffuse axonal inju

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6a6334553fa453f9cb8e0fdcfae4a54
https://doi.org/10.3390/ijms16010758

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A Novel Closed-Head Model of Mild Traumatic Brain Injury Using Focal Primary Overpressure Blast to the Cranium in Mice

Autor: Yunping Deng, Lauren D'Surney, Anton Reiner, Jessica Ferrell, Joshua T. Rogers, Marcia G. Honig, Rafiqul M. Islam, Bowei Deng, Tonia S. Rex, Jessica Hines-Beard, Jeffrey G. Marchetta, Andrea J. Elberger, Wei Bu, Huiling Ren, Nobel Del Mar, Natalie H. Guley

Mild traumatic brain injury (TBI) from focal head impact is the most common form of TBI in humans. Animal models, however, typically use direct impact to the exposed dura or skull, or blast to the entire head. We present a detailed characterization o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faabb15e4b155d5d894839aee841427e
https://europepmc.org/articles/PMC4761824/

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Alcohol exposure during the first two trimesters-equivalent alters the development of corpus callosum projection neurons in the rat

Autor: Andrea J. Elberger, D. J. Livy

Publikováno v: Alcohol. 42:285-293

Children exposed prenatally to alcohol can display a variety of neural deficits, including an altered development of the corpus callosum (CC), the largest interhemispheric axon pathway in the brain. Furthermore, these children show functional abnorma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07c37b737ec2e2914dded12baf2d0652
https://doi.org/10.1016/j.alcohol.2008.04.002

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Combined exposure to nicotine and ethanol throughout full gestation results in enhanced acquisition of nicotine self-administration in young adult rat offspring

Autor: Shannon G. Matta, Andrea J. Elberger

Publikováno v: Psychopharmacology. 193:199-213

Epidemiological evidence shows positive correlation between either maternal cigarette smoking or alcohol consumption on subsequent drug-taking behavior in offspring. However, the consequences of full gestational exposure to both drugs have not been s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a41287897aab2200886e6d38a05246b
https://doi.org/10.1007/s00213-007-0767-2

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Prenatal alcohol exposure delays the development of the cortical barrel field in neonatal rats

Autor: Cheng X. Li, Tyson D. Chappell, Robert S. Waters, Andrea J. Elberger, Cecilia P. Margret, Shannon G. Matta

Publikováno v: Experimental Brain Research. 172:1-13

In-utero alcohol exposure produces sensorimotor developmental abnormalities that often persist into adulthood. The rodent cortical barrel field associated with the representation of the body surface was used as our model system to examine the effect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eca5372cda281188bcdfae195ef0211a
https://doi.org/10.1007/s00221-005-0319-0

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Prenatal alcohol exposure (PAE) reduces the size of the forepaw representation in forepaw barrel subfield (FBS) cortex in neonatal rats: relationship between periphery and central representation

Autor: Tyson D. Chappell, Taha A. Jan, Shannon G. Matta, Cheng X. Li, Andrea J. Elberger, Robert S. Waters, Cecilia P. Margret

Publikováno v: Experimental Brain Research. 172:387-396

Prenatal alcohol exposure (PAE) alters limb development that may lead to structural and functional abnormalities of the limb reported in children diagnosed with Fetal Alcohol Spectrum Disorder. To determine whether PAE alters the central representati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d855f48168ef1b57eedbe0590619f63
https://doi.org/10.1007/s00221-005-0339-9

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Prenatal alcohol exposure alters the size, but not the pattern, of the whisker representation in neonatal rat barrel cortex

Autor: Shannon G. Matta, Tyson D. Chappell, Cecilia P. Margret, Robert S. Waters, Andrea J. Elberger, Cheng X. Li

Publikováno v: Experimental Brain Research. 165:167-178

Maternal alcohol exposure results in a variety of neurodevelopmental abnormalities that include cognitive and sensorimotor dysfunctions that often persist into adulthood. Many reports of central nervous system disturbances associated within a clinica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c84ab44b0fe97d1567eee6705c95bba
https://doi.org/10.1007/s00221-005-2287-9

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Corticothalamic and thalamocortical pathfinding in the mouse: dependence on intermediate targets and guidance axis

Autor: Jinbo Deng, Andrea J. Elberger

Publikováno v: Anatomy and Embryology. 207:177-192

Recently, increasing attention has been paid to the study of intermediate targets and their relay guidance role in long-range pathfinding. In the present study, mechanisms of corticothalamic and thalamocortical pathfinding were investigated in C57BL/

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac6693d1230b95556f0e62b6b166a648
https://doi.org/10.1007/s00429-003-0338-1

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Corpus callosum and visual cortex of mice with deletion of the NMDA-NR1 receptor

Autor: Jinbo Deng, Andrea J. Elberger

Publikováno v: Developmental Brain Research. 144:135-150

Offspring of transgenic mice with deletion of the NMDA-NR1 (NR1) receptor received prenatal alcohol exposure during most of gestation. Before and after birth, offspring were sacrificed in order to examine the morphological consequences of the prenata

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0fed81a5817118076fd2427baef3c4c3
https://doi.org/10.1016/s0165-3806(03)00157-3

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