Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Andrea J Schauenburg"'
Autor:
Alexander Greenshields-Watson, Meriem Attaf, Bruce J. MacLachlan, Thomas Whalley, Cristina Rius, Aaron Wall, Angharad Lloyd, Hywel Hughes, Kathryn E. Strange, Georgina H. Mason, Andrea J. Schauenburg, Sarah L. Hulin-Curtis, James Geary, Yuan Chen, Sarah N. Lauder, Kathryn Smart, Dhanasekaran Vijaykrishna, Miguel L. Grau, Mikhail Shugay, Robert Andrews, Garry Dolton, Pierre J. Rizkallah, Awen M. Gallimore, Andrew K. Sewell, Andrew J. Godkin, David K. Cole
Publikováno v:
Cell Reports, Vol 32, Iss 2, Pp 107885- (2020)
Summary: T cell recognition of peptides presented by human leukocyte antigens (HLAs) is mediated by the highly variable T cell receptor (TCR). Despite this built-in TCR variability, individuals can mount immune responses against viral epitopes by usi
Externí odkaz:
https://doaj.org/article/ac1881b0cc804226bb104e9cab830657
Autor:
Nicholas Jones, James G. Cronin, Garry Dolton, Silvia Panetti, Andrea J. Schauenburg, Sarah A. E. Galloway, Andrew K. Sewell, David K. Cole, Catherine A. Thornton, Nigel J. Francis
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Linking immunometabolic adaptation to T-cell function provides insight for the development of new therapeutic approaches in multiple disease settings. T-cell activation and downstream effector functions of CD4+ and CD8+ T-cells are controlled by the
Externí odkaz:
https://doaj.org/article/4e275e64803946f49058ddf4bb81a441
Autor:
Alexander, Greenshields-Watson, Meriem, Attaf, Bruce J, MacLachlan, Thomas, Whalley, Cristina, Rius, Aaron, Wall, Angharad, Lloyd, Hywel, Hughes, Kathryn E, Strange, Georgina H, Mason, Andrea J, Schauenburg, Sarah L, Hulin-Curtis, James, Geary, Yuan, Chen, Sarah N, Lauder, Kathryn, Smart, Dhanasekaran, Vijaykrishna, Miguel L, Grau, Mikhail, Shugay, Robert, Andrews, Garry, Dolton, Pierre J, Rizkallah, Awen M, Gallimore, Andrew K, Sewell, Andrew J, Godkin, David K, Cole
Publikováno v:
Cell Reports
Summary T cell recognition of peptides presented by human leukocyte antigens (HLAs) is mediated by the highly variable T cell receptor (TCR). Despite this built-in TCR variability, individuals can mount immune responses against viral epitopes by usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eb3a31384ca81261b808e1aa2395f38d
https://pubmed.ncbi.nlm.nih.gov/32668259
https://pubmed.ncbi.nlm.nih.gov/32668259
Autor:
Florian, Madura, Pierre J, Rizkallah, Mateusz, Legut, Christopher J, Holland, Anna, Fuller, Anna, Bulek, Andrea J, Schauenburg, Andrew, Trimby, Jade R, Hopkins, Stephen A, Wells, Andrew, Godkin, John J, Miles, Malkit, Sami, Yi, Li, Nathaniel, Liddy, Bent K, Jakobsen, E Joel, Loveridge, David K, Cole, Andrew K, Sewell
Publikováno v:
European Journal of Immunology
The HLA‐A*02:01‐restricted decapeptide EAAGIGILTV, derived from melanoma antigen recognized by T‐cells‐1 (MART‐1) protein, represents one of the best‐studied tumor associated T‐cell epitopes, but clinical results targeting this peptide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4cdfe2ebbf2aa64cc7714dc26e19d1ee
https://pubmed.ncbi.nlm.nih.gov/31091334
https://pubmed.ncbi.nlm.nih.gov/31091334
Autor:
Florian, Madura, Pierre J, Rizkallah, Christopher J, Holland, Anna, Fuller, Anna, Bulek, Andrew J, Godkin, Andrea J, Schauenburg, David K, Cole, Andrew K, Sewell
Publikováno v:
European Journal of Immunology
Although it has been shown that human tumor-associated, HLA anchor residue modified "heteroclitic" peptides may induce stronger immune responses than wild-type peptides in cancer vaccine trials, it has also been shown that some T cells primed with th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c654c7e9c53eccf88358e19a035b622c
http://europepmc.org/articles/PMC4357396
http://europepmc.org/articles/PMC4357396
Autor:
David K Cole, Anna Fuller, Andrew K Sewell, Pierre J Rizkallah, Valentina Bianchi, Andrea J Schauenburg, Georgina H Mason, Alexander Greenshields-Watson, Bruce J. MacLachlan
Publikováno v:
Journal of Visualized Experiments : JoVE
Human CD8+ cytotoxic T lymphocytes (CTLs) are known to play an important role in tumor control. In order to carry out this function, the cell surface-expressed T-cell receptor (TCR) must functionally recognize human leukocyte antigen (HLA)-restricted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f53de5e77e2d90a67eb72ae7e94fa1c2
http://europepmc.org/articles/PMC5408581
http://europepmc.org/articles/PMC5408581
Autor:
Katie, Tungatt, Valentina, Bianchi, Michael D, Crowther, Wendy E, Powell, Andrea J, Schauenburg, Andrew, Trimby, Marco, Donia, John J, Miles, Christopher J, Holland, David K, Cole, Andrew J, Godkin, Mark, Peakman, Per Thor, Straten, Inge Marie, Svane, Andrew K, Sewell, Garry, Dolton
Publikováno v:
The Journal of Immunology Author Choice
Fluorochrome-conjugated peptide–MHC (pMHC) multimers are commonly used in combination with flow cytometry for direct ex vivo visualization and characterization of Ag-specific T cells, but these reagents can fail to stain cells when TCR affinity and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e02e55ba819c5fddd04758526277c040
https://pubmed.ncbi.nlm.nih.gov/25452566
https://pubmed.ncbi.nlm.nih.gov/25452566