Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Andrea J Luker"'
Autor:
Andrea J. Luker, Abigail Wukitch, Joseph M. Kulinski, Sundar Ganesan, Juraj Kabat, Justin Lack, Pamela Frischmeyer-Guerrerio, Dean D. Metcalfe, Ana Olivera
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The successful development of germinal centers (GC) relies heavily on innate mechanisms to amplify the initial inflammatory cascade. In addition to their role in antigen presentation, innate cells are essential for the redirection of circulating lymp
Externí odkaz:
https://doaj.org/article/d8c9be8b0eb9405087e8bc07eb6babcf
Autor:
Andrea J. Luker, Laura J. Graham, Timothy M. Smith, Carmen Camarena, Matt P. Zellner, Jamie-Jean S. Gilmer, Sheela R. Damle, Daniel H. Conrad, Harry D. Bear, Rebecca K. Martin
Publikováno v:
BMC Immunology, Vol 21, Iss 1, Pp 1-15 (2020)
Abstract Background Myeloid derived suppressor cells (MDSCs) present a significant obstacle to cancer immunotherapy because they dampen anti-tumor cytotoxic T cell responses. Previous groups, including our own, have reported on the myelo-depletive ef
Externí odkaz:
https://doaj.org/article/8705275c0da24e8995eee5018ccbc1c7
Autor:
Rebecca K. Martin, Sheela R. Damle, Yolander A. Valentine, Matthew P. Zellner, Briana N. James, Joseph C. Lownik, Andrea J. Luker, Elijah H. Davis, Martha M. DeMeules, Laura M. Khandjian, Fred D. Finkelman, Joseph F. Urban, Jr., Daniel H. Conrad
Publikováno v:
Cell Reports, Vol 22, Iss 7, Pp 1824-1834 (2018)
Summary: Helminth infection is known for generating large amounts of poly-specific IgE. Here we demonstrate that innate-like B1 cells are responsible for this IgE production during infection with the nematode parasites Nippostrongylus brasiliensis an
Externí odkaz:
https://doaj.org/article/f4577ef0704b41a9a257d4dd0468027d
Publikováno v:
F1000Research, Vol 8 (2019)
Immunoglobulin E (IgE), though constitutively present at low levels, is most commonly studied in atopic disease where it plays a vital role in mast cell degranulation and in initiating a T helper 2 (Th2) response. With the advent of better detection
Externí odkaz:
https://doaj.org/article/fbc47ea0aa7f402ca88ff280fb390de5
Autor:
Joseph C. Lownik, Lauren Folgosa Cooley, Riham El Sayed, Andrea J. Luker, Costantino Pitzalis, Rebecca K. Martin, Mohey Eldin M. El Shikh, Andreas Hutloff, Daniel H. Conrad, Sheela R. Damle
Publikováno v:
The Journal of Immunology. 199:2305-2315
The proper regulation of ICOS and ICOS ligand (ICOSL) has been shown to be essential for maintaining proper immune homeostasis. Loss of either protein results in defective humoral immunity, and overexpression of ICOS results in aberrant Ab production
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::711d1ec0ea8193b4518bc33ea0ff8e75
https://doi.org/10.4049/jimmunol.1700833
https://doi.org/10.4049/jimmunol.1700833
Autor:
Andrea J Luker, Laura J Graham, Matthew P Zellner, Jamie-Jean S Gilmer, Sheela R Damle, Daniel H Conrad, Rebecca K Martin, Harry D Bear
Background: Myeloid derived suppressor cells (MDSC) represent a significant hurdle to cancer immunotherapy because they dampen anti-tumor cytotoxic T cell responses. Previous groups, including our own, have reported on the myelo-depletive effects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::535655981f3d0a2a6ca48d1ddc2f2a90
https://doi.org/10.21203/rs.2.15818/v1
https://doi.org/10.21203/rs.2.15818/v1
Autor:
Andrea J. Luker, Daniel H. Conrad, Jamie-Jean S. Gilmer, Harry D. Bear, Rebecca K. Martin, Matt P. Zellner, Timothy M. Smith, Laura Graham, Carmen Camarena, Sheela R. Damle
Publikováno v:
BMC Immunology
BMC Immunology, Vol 21, Iss 1, Pp 1-15 (2020)
BMC Immunology, Vol 21, Iss 1, Pp 1-15 (2020)
Background Myeloid derived suppressor cells (MDSCs) present a significant obstacle to cancer immunotherapy because they dampen anti-tumor cytotoxic T cell responses. Previous groups, including our own, have reported on the myelo-depletive effects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0c479c83e1b42c2bc4eede0000911fb
https://pubmed.ncbi.nlm.nih.gov/32106810
https://pubmed.ncbi.nlm.nih.gov/32106810
Publikováno v:
The Journal of Immunology. 202:119.7-119.7
Notoriously known for its involvement in type I hypersensitivities, Antigen (Ag)-specific IgE mediates a variety of mild to severe responses, including asthma. Ag-specific IgE is additionally important for immunity against gastrointestinal helminths,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0a24b04204651c67f0eb90ca4c5330a
https://doi.org/10.4049/jimmunol.202.supp.119.7
https://doi.org/10.4049/jimmunol.202.supp.119.7
Autor:
Rebecca Martin, Sheela R. Damle, Yolander A. Valentine, Andrea J. Luker, Joseph C. Lownik, Joseph F. Urban, Daniel H. Conrad
Publikováno v:
The Journal of Immunology. 198:62.4-62.4
Helminth infection is known for generating large amounts of poly-specific IgE. Previously we reported that innate-like B1 cells are responsible for poly-specific IgE production during infection with the nematode parasites Nippostrongylus brasiliensis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36ec5ee8752c1829736d8ab82a584f07
https://doi.org/10.4049/jimmunol.198.supp.62.4
https://doi.org/10.4049/jimmunol.198.supp.62.4
Autor:
Luker, Andrea J.1,2 (AUTHOR), Graham, Laura J.1,2 (AUTHOR), Smith, Timothy M.1,2 (AUTHOR), Camarena, Carmen1 (AUTHOR), Zellner, Matt P.1 (AUTHOR), Gilmer, Jamie-Jean S.3 (AUTHOR), Damle, Sheela R.1,2 (AUTHOR), Conrad, Daniel H.1,2 (AUTHOR), Bear, Harry D.1,2,4 (AUTHOR), Martin, Rebecca K.1,2 (AUTHOR) rebecca.martin@vcuhealth.org
Publikováno v:
BMC Immunology. 2/27/2020, Vol. 21 Issue 1, p1-15. 15p.