Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Andrea Hamann"'
Autor:
Jana Key, Suzana Gispert, Arvind Reddy Kandi, Daniela Heinz, Andrea Hamann, Heinz D. Osiewacz, David Meierhofer, Georg Auburger
Publikováno v:
Biomolecules, Vol 14, Iss 2, p 241 (2024)
The serine peptidase CLPP is conserved among bacteria, chloroplasts, and mitochondria. In humans and mice, its loss causes Perrault syndrome, which presents with growth deficits, infertility, deafness, and ataxia. In the filamentous fungus Podospora
Externí odkaz:
https://doaj.org/article/60dd4f20399d43fa909a042f34ffada4
Publikováno v:
Journal of Fungi, Vol 8, Iss 10, p 1015 (2022)
The formation of fruiting bodies is a highly regulated process that requires the coordinated formation of different cell types. By analyzing developmental mutants, many developmental factors have already been identified. Yet, a complete understanding
Externí odkaz:
https://doaj.org/article/df68ad74507a447c9bb54d192305ada3
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Organismic aging is known to be controlled by genetic and environmental traits. Pathways involved in the control of cellular metabolism play a crucial role. Previously, we identified a role of PaCLPP, a mitochondrial matrix protease, in the control o
Externí odkaz:
https://doaj.org/article/bf9024ab10f84076a1b8615301de7690
Publikováno v:
Cells, Vol 11, Iss 3, p 519 (2022)
The maintenance of cellular homeostasis over time is essential to avoid the degeneration of biological systems leading to aging and disease. Several interconnected pathways are active in this kind of quality control. One of them is autophagy, the vac
Externí odkaz:
https://doaj.org/article/f6c054414ffa411ab2808e9ffcf9aadf
Publikováno v:
Cells, Vol 10, Iss 10, p 2775 (2021)
Mitochondria are ubiquitous organelles of eukaryotic organisms with a number of essential functions, including synthesis of iron-sulfur clusters, amino acids, lipids, and adenosine triphosphate (ATP). During aging of the fungal aging model Podospora
Externí odkaz:
https://doaj.org/article/5ff54ceb5fea4576877f81fe49ec1293
Publikováno v:
BMC Bioinformatics, Vol 18, Iss 1, Pp 1-15 (2017)
Abstract Background Autophagy is a conserved molecular pathway involved in the degradation and recycling of cellular components. It is active either as response to starvation or molecular damage. Evidence is emerging that autophagy plays a key role i
Externí odkaz:
https://doaj.org/article/892fe586ee054d62951184c26631dcc2
Publikováno v:
Frontiers in Genetics, Vol 7 (2016)
The mitochondrial permeability transition pore plays a key role in programmed cell death and the induction of autophagy. Opening of the mPTP is regulated by the mitochondrial peptidyl prolyl-cis,trans-isomerase cyclophilin D (CYPD). Previously it was
Externí odkaz:
https://doaj.org/article/bffc45f1c98b4efc9ad26187ca914bc7
Publikováno v:
PLoS ONE, Vol 8, Iss 12 (2013)
Externí odkaz:
https://doaj.org/article/9336cb82253d430a844cf74eb96910f3
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83109 (2013)
Aging of biological systems is controlled by various processes which have a potential impact on gene expression. Here we report a genome-wide transcriptome analysis of the fungal aging model Podospora anserina. Total RNA of three individuals of defin
Externí odkaz:
https://doaj.org/article/0bb909bf5b3e4a179486fcac66a56d57
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49292 (2012)
The regulation of cellular copper homeostasis is crucial in biology. Impairments lead to severe dysfunctions and are known to affect aging and development. Previously, a loss-of-function mutation in the gene encoding the copper-sensing and copper-reg
Externí odkaz:
https://doaj.org/article/1e2a24a2b9f84e02984ffa8cf19a8dad