Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Andrea Härzschel"'
Autor:
Julia C. Gutjahr, Elisabeth Bayer, Xiaobing Yu, Julia M. Laufer, Jan P. Höpner, Suzana Tesanovic, Andrea Härzschel, Georg Auer, Tanja Rieß, Astrid Salmhofer, Eva Szenes, Theresa Haslauer, Valerie Durand-Onayli, Andrea Ramspacher, Sandra P. Pennisi, Marc Artinger, Nadja Zaborsky, Alexandre Chigaev, Fritz Aberger, Daniel Neureiter, Lisa Pleyer, Daniel F. Legler, Veronique Orian-Rousseau, Richard Greil, Tanja N. Hartmann
Publikováno v:
Haematologica, Vol 106, Iss 8 (2020)
Adhesive properties of leukemia cells shape the degree of organ infiltration and the extent of leukocytosis. CD44 and the integrin VLA-4, a CD49d/CD29 heterodimer, are important factors of progenitor cell adhesion in bone marrow (BM). Here, we report
Externí odkaz:
https://doaj.org/article/9bf54160724d40848f05cabcbde9c7ee
Autor:
Jared A. Cohen, Riccardo Bomben, Federico Pozzo, Erika Tissino, Andrea Härzschel, Tanja Nicole Hartmann, Antonella Zucchetto, Valter Gattei
Publikováno v:
Cancers, Vol 12, Iss 4, p 894 (2020)
Chronic lymphocytic leukemia (CLL) is a heterogeneous disease with a variable clinical course. Novel biomarkers discovered over the past 20 years have revolutionized the way clinicians approach prognostication and treatment especially in the chemothe
Externí odkaz:
https://doaj.org/article/a0288757e8b742ee9bae384a0501239e
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 6, p 2206 (2020)
Lineage commitment and differentiation of hematopoietic cells takes place in well-defined microenvironmental surroundings. Communication with other cell types is a vital prerequisite for the normal functions of the immune system, while disturbances i
Externí odkaz:
https://doaj.org/article/f881910aa7f14ba7a47a2219b415dfe3
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 12, p 4041 (2018)
Emerging evidence suggests that crosstalk between hematologic tumor cells and the tumor microenvironment contributes to leukemia and lymphoma cell migration, survival, and proliferation. The supportive tumor cell-microenvironment interactions and the
Externí odkaz:
https://doaj.org/article/60024e989bd6475c90b7a7942421f3a4
Autor:
Andrea Härzschel, Lixia Li, Peter W Krenn, Eva Szenes-Nagy, Geoffroy Andrieux, Elisabeth Bayer, Dietmar Pfeifer, Laura Polcik, Ursula Denk, Jan P Höpner, Elif Karabatak, Danielle-Justine Danner, Simone Tangermann, Lukas Kenner, Hassan Jumaa, Richard Greil, Melanie Börries, Raphael Ruppert, Palash C Maity, Tanja Nicole Hartmann
Publikováno v:
Journal of Leukocyte Biology
Integrin-mediated interactions between hematopoietic cells and their microenvironment are important for the development and function of immune cells. Here, the role of the integrin adaptor Kindlin-3 in B cell homeostasis is studied. Comparing the ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eb32aeee778a60982ee5379aa0fd097
https://hdl.handle.net/21.11116/0000-000A-11B1-A21.11116/0000-000A-11AF-E21.11116/0000-000A-11B2-9
https://hdl.handle.net/21.11116/0000-000A-11B1-A21.11116/0000-000A-11AF-E21.11116/0000-000A-11B2-9
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 6, p 2206 (2020)
International Journal of Molecular Sciences, Vol 21, Iss 6, p 2206 (2020)
Lineage commitment and differentiation of hematopoietic cells takes place in well-defined microenvironmental surroundings. Communication with other cell types is a vital prerequisite for the normal functions of the immune system, while disturbances i
Autor:
Marc Artinger, Véronique Orian-Rousseau, Lisa Pleyer, Fritz Aberger, Suzana Tesanovic, Elisabeth Bayer, Daniel Neureiter, Andrea Härzschel, Valerie Durand-Onayli, Tanja Rieß, Jan Philip Höpner, Alexandre Chigaev, Georg Auer, Julia Christine Gutjahr, Nadja Zaborsky, Richard Greil, Daniel F. Legler, Julia M. Laufer, Sandra Pennisi, Astrid Salmhofer, Xiaobing Yu, Andrea Ramspacher, Tanja Nicole Hartmann, Theresa Haslauer, Eva Szenes
Publikováno v:
Haematologica, 106 (8), 2102-2113
Haematologica
Haematologica
Adhesive properties of leukemia cells shape the degree of organ infiltration and the extent of leukocytosis. CD44 and the integrin VLA-4, a CD49d/CD29 heterodimer, are important factors of progenitor cell adhesion in bone marrow (BM). Here, we report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7bde17c88e6e52bc9f73a02d5ff2aa8
https://publikationen.bibliothek.kit.edu/1000127084
https://publikationen.bibliothek.kit.edu/1000127084
Autor:
Tanja Nicole Hartmann, Ayed O. Ayed, Alexandre Chigaev, Valter Gattei, Gabriele Pozzato, Antonella Zucchetto, Enrico Santinelli, Jan A. Burger, Julia Christine Gutjahr, Massimiliano Postorino, Elisabeth Bayer, Erika Tissino, Riccardo Bomben, Giovanni Del Poeta, Michele Dal Bo, Adrian Wiestner, Elisa Ten Hacken, Dania Benedetti, Pietro Bulian, Inhye E. Ahn, Larry A. Sklar, Andrea Härzschel, Alessandra Ferrajoli, Francesca Rossi, Kari G. Chaffee, Annalisa Chiarenza, Francesco Zaja, Tait D. Shanafelt, Sarah E. M. Herman
Publikováno v:
The Journal of Experimental Medicine
Tissino et al. demonstrate that in chronic lymphocytic leukemia, the VLA-4 (CD49d/CD29) integrin remains activable by B cell receptor stimulation also upon in vitro and in vivo ibrutinib exposure. Clinically, ibrutinib-treated CD49d-positive CLL pati
Autor:
Tanja Nicole Hartmann, Peter W. Krenn, Andrea Härzschel, Geoffroy Andrieux, Danielle-Justine Danner, Raphael Ruppert, Elif Karabatak, Richard Greil, Simone Tangermann, Ursula Denk, Elisabeth Bayer, Melanie Boerries, Lukas Kenner, Alexander Egle, Eva Szenes
Publikováno v:
Blood. 136:46-47
Introduction The development and maturation of B cells is highly dependent on signals provided by the microenvironment of the lymphatic organs. As B cells move from one developmental stage and niche to the next, the integrin family of adhesion molecu
Autor:
Antonella Zucchetto, Jared A. Cohen, Valter Gattei, Erika Tissino, Tanja Nicole Hartmann, Riccardo Bomben, Federico Pozzo, Andrea Härzschel
Publikováno v:
Cancers, Vol 12, Iss 894, p 894 (2020)
Cancers
Cancers
Chronic lymphocytic leukemia (CLL) is a heterogeneous disease with a variable clinical course. Novel biomarkers discovered over the past 20 years have revolutionized the way clinicians approach prognostication and treatment especially in the chemothe